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The map label for this gene is yafC [H]

Identifier: 110680186

GI number: 110680186

Start: 2862800

End: 2863696

Strand: Reverse

Name: yafC [H]

Synonym: RD1_2988

Alternate gene names: 110680186

Gene position: 2863696-2862800 (Counterclockwise)

Preceding gene: 110680187

Following gene: 110680185

Centisome position: 69.29

GC content: 60.54

Gene sequence:

>897_bases
TTGCAAACCAATTGGGACGATTTGAGGATATTCCTCGCGGTCGCACGCGACAATAGCCTGTCCGGGGCAGGAAAGCGGTT
GCGTCTGGATCCGGCGACGGTCGGCAGGCGTATTCAAAAGCTGGAAGCCGCTTTGCAAACCGTTCTGTTTACCAAATCCC
CGCAGGGCTATGCCTTGAGCGAAACCGGACAGGCCCTTCTGGTGCGCGCCGAACAGGCCGAGACCGCGATGCGTGCGGCA
GTGGCCGTGCTGCAGGAACAGTCGGACCGTCTGAGCGGGCAAATTCGCATCGGTGCGCCGGATGGGGCGGCGAATTATCT
GTTGCCCCAGGTCTGTGCCGCGATTCTGAAGGAAAACCCGGATCTGGAAATTCAGATCGTCGCCCTGCCGCGGGTCTTTA
ACCTGTCGCGCCGGGAAGCCGATATGGCGATTGCCGTCAGCGCGCCGACCGCCGGGCGGCTGATCGTGCAGAAAATCACT
GATTACAAGCTGCATCTGGCAGTGTCGCGGGACTACATCCGTGACAACGGGGCGATCCGGTCGGTTGCGGATCTGGCCCG
CCACAATGTGGTGGGCTACATCGCGGATATGATCTTTGACCGCGAACTCGACTATCTCGAAGAGATTGGCCTGACCAAGG
TGCCGCTGGCGTCAAATTCTGTCTCGGTTCAACTCAACCTCATCCGGCAGGGTGGGGGCGTCGGGGTCGTGCATGATTTC
GCCCTGTCCGCAGCCCCCGAGGTTGCGCGCATTTTGACAGATGAAGTCAGCCTGACGCGGGTATTTTACCTGATCCGACA
CGAAGACGACCGGCGCAATGCGCGGCTGCGTCGGTTCGCCGACAGGTTGTGTAACGGTCTGAGGGCCGAAGTTGCGCGCC
TTGAAGCGCTGACTTGA

Upstream 100 bases:

>100_bases
GGTCGCTGCGCGATGCTGGCAGATATAGCCTTGCAAAAATCATCCATAAAGGGCCTTTATGGCAAATTCATTTTGCATAA
ATGCAAGACAGGTGGCGGCA

Downstream 100 bases:

>100_bases
CTTGTTTGCGCTTTGCGGTGACTTTTGAGGGAGCACAACCAGCCAGCCAAGGGGTACATCATGCTTGTTTCTCAAATCCT
GAAAACCAAACAACAGCATG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MQTNWDDLRIFLAVARDNSLSGAGKRLRLDPATVGRRIQKLEAALQTVLFTKSPQGYALSETGQALLVRAEQAETAMRAA
VAVLQEQSDRLSGQIRIGAPDGAANYLLPQVCAAILKENPDLEIQIVALPRVFNLSRREADMAIAVSAPTAGRLIVQKIT
DYKLHLAVSRDYIRDNGAIRSVADLARHNVVGYIADMIFDRELDYLEEIGLTKVPLASNSVSVQLNLIRQGGGVGVVHDF
ALSAAPEVARILTDEVSLTRVFYLIRHEDDRRNARLRRFADRLCNGLRAEVARLEALT

Sequences:

>Translated_298_residues
MQTNWDDLRIFLAVARDNSLSGAGKRLRLDPATVGRRIQKLEAALQTVLFTKSPQGYALSETGQALLVRAEQAETAMRAA
VAVLQEQSDRLSGQIRIGAPDGAANYLLPQVCAAILKENPDLEIQIVALPRVFNLSRREADMAIAVSAPTAGRLIVQKIT
DYKLHLAVSRDYIRDNGAIRSVADLARHNVVGYIADMIFDRELDYLEEIGLTKVPLASNSVSVQLNLIRQGGGVGVVHDF
ALSAAPEVARILTDEVSLTRVFYLIRHEDDRRNARLRRFADRLCNGLRAEVARLEALT
>Mature_298_residues
MQTNWDDLRIFLAVARDNSLSGAGKRLRLDPATVGRRIQKLEAALQTVLFTKSPQGYALSETGQALLVRAEQAETAMRAA
VAVLQEQSDRLSGQIRIGAPDGAANYLLPQVCAAILKENPDLEIQIVALPRVFNLSRREADMAIAVSAPTAGRLIVQKIT
DYKLHLAVSRDYIRDNGAIRSVADLARHNVVGYIADMIFDRELDYLEEIGLTKVPLASNSVSVQLNLIRQGGGVGVVHDF
ALSAAPEVARILTDEVSLTRVFYLIRHEDDRRNARLRRFADRLCNGLRAEVARLEALT

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=23.9057239057239, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789440, Length=241, Percent_Identity=27.3858921161826, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=127, Percent_Identity=27.5590551181102, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081978, Length=185, Percent_Identity=27.5675675675676, Blast_Score=61, Evalue=9e-11,
Organism=Escherichia coli, GI145693193, Length=190, Percent_Identity=24.7368421052632, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32834; Mature: 32834

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTNWDDLRIFLAVARDNSLSGAGKRLRLDPATVGRRIQKLEAALQTVLFTKSPQGYALS
CCCCHHHEEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCEEC
ETGQALLVRAEQAETAMRAAVAVLQEQSDRLSGQIRIGAPDGAANYLLPQVCAAILKENP
CCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
DLEIQIVALPRVFNLSRREADMAIAVSAPTAGRLIVQKITDYKLHLAVSRDYIRDNGAIR
CCEEEEEEECCHHCCCCCCCCEEEEEECCCCCHHHHHHHCCEEEEEEEEHHHHHCCCCHH
SVADLARHNVVGYIADMIFDRELDYLEEIGLTKVPLASNSVSVQLNLIRQGGGVGVVHDF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEECCCCCCCEEEEEEEEECCCCEEEHHHH
ALSAAPEVARILTDEVSLTRVFYLIRHEDDRRNARLRRFADRLCNGLRAEVARLEALT
HHHCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTNWDDLRIFLAVARDNSLSGAGKRLRLDPATVGRRIQKLEAALQTVLFTKSPQGYALS
CCCCHHHEEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCEEC
ETGQALLVRAEQAETAMRAAVAVLQEQSDRLSGQIRIGAPDGAANYLLPQVCAAILKENP
CCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
DLEIQIVALPRVFNLSRREADMAIAVSAPTAGRLIVQKITDYKLHLAVSRDYIRDNGAIR
CCEEEEEEECCHHCCCCCCCCEEEEEECCCCCHHHHHHHCCEEEEEEEEHHHHHCCCCHH
SVADLARHNVVGYIADMIFDRELDYLEEIGLTKVPLASNSVSVQLNLIRQGGGVGVVHDF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEECCCCCCCEEEEEEEEECCCCEEEHHHH
ALSAAPEVARILTDEVSLTRVFYLIRHEDDRRNARLRRFADRLCNGLRAEVARLEALT
HHHCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]