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The map label for this gene is coaD

Identifier: 110680184

GI number: 110680184

Start: 2861718

End: 2862218

Strand: Reverse

Name: coaD

Synonym: RD1_2985

Alternate gene names: 110680184

Gene position: 2862218-2861718 (Counterclockwise)

Preceding gene: 110680185

Following gene: 110680182

Centisome position: 69.25

GC content: 56.49

Gene sequence:

>501_bases
ATGCGCGTTGGCCTTTATCCCGGCACTTTTGATCCCATCACCCTCGGGCATCTCGACATTATTCGGCGCGCAAGCGCGCT
GCTCGACAAACTGGTGATCGGGGTTGCGATCAACCGGGACAAGGGCCCGCTGTTTTGTCTCGAAGAGCGCGTGGCGATGG
TGGAGGCTGAATCCATCAAGATCGCCGCCATGACCGGGCTGGAGATTGTGACCCATCCTTTTGAAAACCTGTTGATTGAT
TGTGCGCGCGATGTTGGCGCGACAGTTATCGTGCGCGGATTGCGCGCGGTGGCGGATTTTGAATACGAATATCAGATGGT
AGGCATGAACCGGCAGTTGGATGATACGATCGAGACCGTGTTCCTGATGGCCGAGGCCGAACATCAGGCCATCGCAAGCA
AACTGGTCAAGGAGATCGCCCGTCTTGGCGGCGACATCGAAAAGTTTGTCACGCCCGAAGTGAACGCGGCCCTTTTGAAC
AAAATCGGCAGGGCGGGTTAA

Upstream 100 bases:

>100_bases
TCATGGGCCATTGAGCCCTTTGCAAACTCACCTGCAAACTCTTGCAAATATTCGCTGACAGTGGTCGTTTGGCCCCAATT
TAAAACGACAGGAGGGTCTG

Downstream 100 bases:

>100_bases
TCCATCACTTTAGAAGTGTTCGATTATATGTTGTTTTTATTGTGAAAATATAATAGAGTAGCCGACTTTGCCTTGCGTAG
CATGCGCAGAGTTCTCGTCA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MRVGLYPGTFDPITLGHLDIIRRASALLDKLVIGVAINRDKGPLFCLEERVAMVEAESIKIAAMTGLEIVTHPFENLLID
CARDVGATVIVRGLRAVADFEYEYQMVGMNRQLDDTIETVFLMAEAEHQAIASKLVKEIARLGGDIEKFVTPEVNAALLN
KIGRAG

Sequences:

>Translated_166_residues
MRVGLYPGTFDPITLGHLDIIRRASALLDKLVIGVAINRDKGPLFCLEERVAMVEAESIKIAAMTGLEIVTHPFENLLID
CARDVGATVIVRGLRAVADFEYEYQMVGMNRQLDDTIETVFLMAEAEHQAIASKLVKEIARLGGDIEKFVTPEVNAALLN
KIGRAG
>Mature_166_residues
MRVGLYPGTFDPITLGHLDIIRRASALLDKLVIGVAINRDKGPLFCLEERVAMVEAESIKIAAMTGLEIVTHPFENLLID
CARDVGATVIVRGLRAVADFEYEYQMVGMNRQLDDTIETVFLMAEAEHQAIASKLVKEIARLGGDIEKFVTPEVNAALLN
KIGRAG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=160, Percent_Identity=46.25, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_ROSDO (Q164T8)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683191.1
- ProteinModelPortal:   Q164T8
- SMR:   Q164T8
- STRING:   Q164T8
- GeneID:   4195614
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2985
- NMPDR:   fig|375451.6.peg.2777
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q164T8
- ProtClustDB:   PRK00168
- BioCyc:   RDEN375451:RD1_2985-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18194; Mature: 18194

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGLYPGTFDPITLGHLDIIRRASALLDKLVIGVAINRDKGPLFCLEERVAMVEAESIK
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHCCEE
IAAMTGLEIVTHPFENLLIDCARDVGATVIVRGLRAVADFEYEYQMVGMNRQLDDTIETV
EEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
FLMAEAEHQAIASKLVKEIARLGGDIEKFVTPEVNAALLNKIGRAG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MRVGLYPGTFDPITLGHLDIIRRASALLDKLVIGVAINRDKGPLFCLEERVAMVEAESIK
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHCCEE
IAAMTGLEIVTHPFENLLIDCARDVGATVIVRGLRAVADFEYEYQMVGMNRQLDDTIETV
EEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
FLMAEAEHQAIASKLVKEIARLGGDIEKFVTPEVNAALLNKIGRAG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA