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The map label for this gene is clpX [H]

Identifier: 110680062

GI number: 110680062

Start: 2725435

End: 2726700

Strand: Reverse

Name: clpX [H]

Synonym: RD1_2857

Alternate gene names: 110680062

Gene position: 2726700-2725435 (Counterclockwise)

Preceding gene: 110680063

Following gene: 110680061

Centisome position: 65.97

GC content: 56.56

Gene sequence:

>1266_bases
ATGGCGACGAATTCAAGCGGAGACGGCAAAAACACGCTATATTGCAGCTTTTGTGGGAAAAGTCAGCATGAAGTGCGCAA
ACTGATCGCCGGCCCGACCGTCTTCATCTGCGATGAATGCGTTGAGTTGTGCATGGATATCATCCGTGAGGAAACCAAGG
CTTCGGGGCTCAAGGCCACTGATGGCGTGCCGACCCCGAAAGACATCTGTGCAGTGCTGGATGATTACGTGATTGGTCAG
GCCATGGCGAAACGCGTTCTGTCGGTGGCGGTGCACAATCACTACAAGCGGCTCAATCACGCGCAAAAAGGCGGCGATAT
TGAACTGGCCAAATCCAACATTCTTTTGATTGGCCCGACTGGTTGCGGTAAAACGCTTCTGGCCCAGACACTTGCGCGCA
TTCTGGACGTTCCTTTCACCATGGCGGATGCCACAACGCTGACCGAAGCGGGCTATGTCGGTGAGGATGTGGAGAATATC
ATTCTCAAGCTCCTGCAATCCTCCGAGTATAATGTCGAACGGGCGCAGCGCGGCATCGTCTATATTGATGAGGTCGACAA
GATCACCCGTAAATCCGAGAACCCCTCGATCACGCGGGATGTATCGGGTGAGGGGGTGCAGCAAGCCTTGCTCAAGCTGA
TGGAAGGCACAGTTGCATCCGTGCCGCCACAGGGCGGTCGCAAACACCCGCAGCAGGAATTCCTGCAGGTCGACACGACG
AACATCCTGTTTATCTGTGGGGGCGCTTTCGCGGGGCTCGACAAGATCATCGCGGCACGCGGCAAGGGTTCGGCGATGGG
ATTCGGTGCTGATGTGCGCGGGAATGATGATCGGGGTGTCGGCGAGATCTTTACCGACCTCGAACCGGAGGACCTGCTGA
AATTTGGGCTGATCCCGGAGTTCGTCGGTCGTCTGCCGGTGCTTGCGACACTCGAAGACCTGGACGAGGACGCGTTGGTC
ACAATCCTGACGCAACCCAAGAACGCGTTGGTGAAGCAATACCAACGCCTGTTCGAACTGGAAGATACCGAACTAACGTT
CACGGATGACGCTCTTTCCGCCATTGCCAAACGGGCGATTGAGCGCAAGACAGGCGCGCGCGGGCTGCGTTCCATCCTTG
AGGACATCCTGCTCGATACCATGTTTGACCTGCCGGGCTTGGAAAGCGTGACAGAGGTCGTGGTGAACGAAGAGGCTGTA
AATTCGGATGCAGCACCTTTGATGATCCATGCCGACGCCAGCAAGGAACCGGCAAGCGCGGGCTAA

Upstream 100 bases:

>100_bases
TTGTGGACGGGCTGGGGCTGGCCTAAACTGATACTAAGGATGGAGGGCGCACCAGATCGCTGGTGGCTCACCAAAGGATG
CGGCACCGGAAAGGTTTCAA

Downstream 100 bases:

>100_bases
CGCGTGCTTTGCGCCCCATCATGAAAACGGGGCACTGAGCCCTGTTTTTCCGTAAGATCGCAATCCCGCTCGACTGATGC
GACCGCCCCGAGCTGTGCTT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MATNSSGDGKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGLKATDGVPTPKDICAVLDDYVIGQ
AMAKRVLSVAVHNHYKRLNHAQKGGDIELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQSSEYNVERAQRGIVYIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDKIIAARGKGSAMGFGADVRGNDDRGVGEIFTDLEPEDLLKFGLIPEFVGRLPVLATLEDLDEDALV
TILTQPKNALVKQYQRLFELEDTELTFTDDALSAIAKRAIERKTGARGLRSILEDILLDTMFDLPGLESVTEVVVNEEAV
NSDAAPLMIHADASKEPASAG

Sequences:

>Translated_421_residues
MATNSSGDGKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGLKATDGVPTPKDICAVLDDYVIGQ
AMAKRVLSVAVHNHYKRLNHAQKGGDIELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQSSEYNVERAQRGIVYIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDKIIAARGKGSAMGFGADVRGNDDRGVGEIFTDLEPEDLLKFGLIPEFVGRLPVLATLEDLDEDALV
TILTQPKNALVKQYQRLFELEDTELTFTDDALSAIAKRAIERKTGARGLRSILEDILLDTMFDLPGLESVTEVVVNEEAV
NSDAAPLMIHADASKEPASAG
>Mature_420_residues
ATNSSGDGKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGLKATDGVPTPKDICAVLDDYVIGQA
MAKRVLSVAVHNHYKRLNHAQKGGDIELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQSSEYNVERAQRGIVYIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLDKIIAARGKGSAMGFGADVRGNDDRGVGEIFTDLEPEDLLKFGLIPEFVGRLPVLATLEDLDEDALVT
ILTQPKNALVKQYQRLFELEDTELTFTDDALSAIAKRAIERKTGARGLRSILEDILLDTMFDLPGLESVTEVVVNEEAVN
SDAAPLMIHADASKEPASAG

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=343, Percent_Identity=52.4781341107872, Blast_Score=320, Evalue=2e-87,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=68.75, Blast_Score=582, Evalue=1e-167,
Organism=Escherichia coli, GI1790366, Length=121, Percent_Identity=39.6694214876033, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=48.0769230769231, Blast_Score=281, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=48.0769230769231, Blast_Score=281, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=37.3401534526854, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=39.6761133603239, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=37.7049180327869, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=50.6289308176101, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=50.6289308176101, Blast_Score=307, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45434; Mature: 45303

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATNSSGDGKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGLKAT
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DGVPTPKDICAVLDDYVIGQAMAKRVLSVAVHNHYKRLNHAQKGGDIELAKSNILLIGPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECC
GCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQSSEYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCE
YIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDKIIAARGKGSAMGFGADVRGNDDRGVGEIFTDLEPEDLLKFGLIPE
CEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCHH
FVGRLPVLATLEDLDEDALVTILTQPKNALVKQYQRLFELEDTELTFTDDALSAIAKRAI
HHCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
ERKTGARGLRSILEDILLDTMFDLPGLESVTEVVVNEEAVNSDAAPLMIHADASKEPASA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCC
G
C
>Mature Secondary Structure 
ATNSSGDGKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKASGLKAT
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DGVPTPKDICAVLDDYVIGQAMAKRVLSVAVHNHYKRLNHAQKGGDIELAKSNILLIGPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECC
GCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQSSEYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCE
YIDEVDKITRKSENPSITRDVSGEGVQQALLKLMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDKIIAARGKGSAMGFGADVRGNDDRGVGEIFTDLEPEDLLKFGLIPE
CEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCHH
FVGRLPVLATLEDLDEDALVTILTQPKNALVKQYQRLFELEDTELTFTDDALSAIAKRAI
HHCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
ERKTGARGLRSILEDILLDTMFDLPGLESVTEVVVNEEAVNSDAAPLMIHADASKEPASA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA