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The map label for this gene is dehH1 [H]

Identifier: 110680036

GI number: 110680036

Start: 2701178

End: 2702050

Strand: Direct

Name: dehH1 [H]

Synonym: RD1_2829

Alternate gene names: 110680036

Gene position: 2701178-2702050 (Clockwise)

Preceding gene: 110680035

Following gene: 110680041

Centisome position: 65.35

GC content: 59.34

Gene sequence:

>873_bases
ATGTTTGCCGGGTTCGAGGTGGGCGACGCCTTGGTCAACGGACAGTCCGTCCACTATCGCGCTGGTGGGCAAGGCGCTCC
GGTGCTGTTGTTGCATGGGTTCCCCCAAACCCATGTGATGTGGCATGCGGTCGCCACGCGGCTTGCCAAAAACTTCTCCG
TCGTCGCATCCGACCTCCGGGGCTATGGGCACAGCAGCAAGCCGACGGGCACGGAGGCCTACAGCTTTCGCAATATGGCC
AGCGATCAGATCGCCCTGATGCATGCGCTGGGACATGACAGGTTTCATGTGGTCGGCCATGATCGAGGGGGACGTGTCGC
ACATCGTATGGCACTGGATCATCCAAAGGCCATACAAAGCCTGACGGTGATGGACATCGTCCCGACCCATCTCCTGCTGG
ATGATTTGTCCAAAGAAGTGGCGGAGGCCTATTATCACTGGTTCTTTCTGGCCCAGCCTGCCCCCTTCCCGGAAACGATG
ATCGGACATGATCCGGATGCGTTTTTCGAACGGTGCCTGCTCGGCTTTGGGGCGGCACAGCTGTCGGATTTTGATGCAGA
TGCGCTGGAGGCCTATCGTGCGGCATGGCGTAACCCCGAGACGATCCGCGCGATGTGTGCGGATTACCGTGCAGCGCTGC
ACGTTGATTTCACCCATGATTCGCAGGATCACGGTCGCCGCATAGATGTGCCCGCCCTTGTCCTCTTTGGGGCCGAGGGC
GCCATGGCACAATCCTACAACGTCGCTGACACATGGCGCGAAAAGCTGTCCCAGATGAAAGCCCTGGCGATTCCGGGGGG
GCATTTCTTCATCGACCAGTCACCGGATGAAACGCACCATGTGCTGGAGACGTTCCTGTCCGAAATCACCTGA

Upstream 100 bases:

>100_bases
AGGATGATGATGCGATACATTCACCGAACGAGAAATATGACCTTGAGAGCTTTCACAAAGGTGCGCGCAGCTGGGCGCGA
ATCCTCGCGGCGCTGACCTG

Downstream 100 bases:

>100_bases
TCCCTATTGCCGCAGGATGCCGGGGGGTCTTTGACATTCCTGCGCTTCCAAAGCGTCGACCGCCCGACAGAACCCGGTCA
GTGAAAAACGAGACAGTGCA

Product: haloacetate dehalogenase H-1, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MFAGFEVGDALVNGQSVHYRAGGQGAPVLLLHGFPQTHVMWHAVATRLAKNFSVVASDLRGYGHSSKPTGTEAYSFRNMA
SDQIALMHALGHDRFHVVGHDRGGRVAHRMALDHPKAIQSLTVMDIVPTHLLLDDLSKEVAEAYYHWFFLAQPAPFPETM
IGHDPDAFFERCLLGFGAAQLSDFDADALEAYRAAWRNPETIRAMCADYRAALHVDFTHDSQDHGRRIDVPALVLFGAEG
AMAQSYNVADTWREKLSQMKALAIPGGHFFIDQSPDETHHVLETFLSEIT

Sequences:

>Translated_290_residues
MFAGFEVGDALVNGQSVHYRAGGQGAPVLLLHGFPQTHVMWHAVATRLAKNFSVVASDLRGYGHSSKPTGTEAYSFRNMA
SDQIALMHALGHDRFHVVGHDRGGRVAHRMALDHPKAIQSLTVMDIVPTHLLLDDLSKEVAEAYYHWFFLAQPAPFPETM
IGHDPDAFFERCLLGFGAAQLSDFDADALEAYRAAWRNPETIRAMCADYRAALHVDFTHDSQDHGRRIDVPALVLFGAEG
AMAQSYNVADTWREKLSQMKALAIPGGHFFIDQSPDETHHVLETFLSEIT
>Mature_290_residues
MFAGFEVGDALVNGQSVHYRAGGQGAPVLLLHGFPQTHVMWHAVATRLAKNFSVVASDLRGYGHSSKPTGTEAYSFRNMA
SDQIALMHALGHDRFHVVGHDRGGRVAHRMALDHPKAIQSLTVMDIVPTHLLLDDLSKEVAEAYYHWFFLAQPAPFPETM
IGHDPDAFFERCLLGFGAAQLSDFDADALEAYRAAWRNPETIRAMCADYRAALHVDFTHDSQDHGRRIDVPALVLFGAEG
AMAQSYNVADTWREKLSQMKALAIPGGHFFIDQSPDETHHVLETFLSEIT

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=292, Percent_Identity=26.7123287671233, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI218777840, Length=282, Percent_Identity=25.531914893617, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI13376164, Length=282, Percent_Identity=25.531914893617, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27597073, Length=110, Percent_Identity=30.9090909090909, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554012, Length=280, Percent_Identity=25.3571428571429, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324392, Length=278, Percent_Identity=26.6187050359712, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32121; Mature: 32121

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAGFEVGDALVNGQSVHYRAGGQGAPVLLLHGFPQTHVMWHAVATRLAKNFSVVASDLR
CCCCCCCCHHHCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
GYGHSSKPTGTEAYSFRNMASDQIALMHALGHDRFHVVGHDRGGRVAHRMALDHPKAIQS
CCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCHHHHHH
LTVMDIVPTHLLLDDLSKEVAEAYYHWFFLAQPAPFPETMIGHDPDAFFERCLLGFGAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCHHHHHHHHHHHCCHHH
LSDFDADALEAYRAAWRNPETIRAMCADYRAALHVDFTHDSQDHGRRIDVPALVLFGAEG
HCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEEECCCCCCCCCEECCCEEEEECCCC
AMAQSYNVADTWREKLSQMKALAIPGGHFFIDQSPDETHHVLETFLSEIT
CCCCCCCHHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFAGFEVGDALVNGQSVHYRAGGQGAPVLLLHGFPQTHVMWHAVATRLAKNFSVVASDLR
CCCCCCCCHHHCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
GYGHSSKPTGTEAYSFRNMASDQIALMHALGHDRFHVVGHDRGGRVAHRMALDHPKAIQS
CCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCHHHHHH
LTVMDIVPTHLLLDDLSKEVAEAYYHWFFLAQPAPFPETMIGHDPDAFFERCLLGFGAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCCHHHHHHHHHHHCCHHH
LSDFDADALEAYRAAWRNPETIRAMCADYRAALHVDFTHDSQDHGRRIDVPALVLFGAEG
HCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEEECCCCCCCCCEECCCEEEEECCCC
AMAQSYNVADTWREKLSQMKALAIPGGHFFIDQSPDETHHVLETFLSEIT
CCCCCCCHHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512562 [H]