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The map label for this gene is btuC [C]

Identifier: 110679897

GI number: 110679897

Start: 2548884

End: 2549954

Strand: Direct

Name: btuC [C]

Synonym: RD1_2674

Alternate gene names: 110679897

Gene position: 2548884-2549954 (Clockwise)

Preceding gene: 110679896

Following gene: 110679898

Centisome position: 61.67

GC content: 60.97

Gene sequence:

>1071_bases
ATGACAGTTCAAACAACAAACCCCGATCCCGCGCGCGACATCGTCGGCGCCTATAGGCGGCGCTCTGCCAAACGCGTGGC
CCTTGTGTGCCTTGCAGCCGTTGCGCTGGGTGCCATGATTGTCATCGACATTATCACCGGACCGGCGGAGCTTGGGTTCC
TGCGCACCTTGCATGTCATTCTTGATCCTTCGATCGCCACCGCCAAGGAAGCGGTCATCATCTGGGATTTGCGCCTGCCG
GTGGCCTTGATGGCGGTTGTGGTGGGGGCAATGCTGGGCGTTGCCGGCGCGGAGATGCAGACGATCCTGAACAATCCGCT
GGCGGACCCTTTCACGCTCGGCCTGTCCTCGGCGGCGTCCTTCGGGGCGGCGCTTGCAATTGTCCTTGGCTTTTCGGTGA
TCCCGGCTGTTGGCGGCCTGCTGGTCACGGTCAACGCCTTCATGTTTTCGCTGTTTGCCTCACTGGCGCTCTTTGCCTTT
ACCAAATTGCGCGGGGTGACGCCCGAAGCGATGATCCTCGTGGGTATCGCGATGCTCTTTAGTTTCAACGCCTTGCTGGC
CTTTCTGCAATACGGCGCGTCCGAACTGGAATTGGCGCAGCTGATCTTCTGGCAGATGGGCTCGCTGGCGCGCGCCACAT
GGGCCAAGGTTGGCATCTGTCTGGTGGTACTGGCCATCGTGCTGCCCTATTTCCTATCACGCTCCTGGGCGCTTACGGCC
CTGCGCATGGGCGAGGACAAGGCAGCGGCGCTTGGCGTCAATGTCGCACTGCTGCGGCTGGCCGTTCTGGCGGGCGTGTC
GCTGCTGTCTGCGGTTGCCGTGTCCTTTGTGGGCGCCATTGCATTTGTCGGCCTTGTCGGACCGCATATCGCACGCCTCA
TCGTCGGGGAAGACCAGCGCGGTTTTCTGCCCCTGTCCGCCCTGATGGGCGCGCTGATCCTGTCAGCAACTTCCATCGTG
TCCAAGGCGATCACACCGGGCATCGTCTATCCCATCGGCATGATCACCTCACTGATTGGCATTCCCTTCTTTGTCAGCCT
CATTCTGAGCCAACGCAAAAGGCACTGGTAA

Upstream 100 bases:

>100_bases
CCCTATGAAAACTCCGGACAGTTCTGGCTGAGTGCCAGCGCGCCGGGCAACTGAGGGTATGCCTGTGGCGGGTGTCATAC
CTGCCACAGGATGCTGATTT

Downstream 100 bases:

>100_bases
TGACCCTTTTCGCAACCGATCTGACCTTTGCCTATGACAGCCGCCGCGTGCTTTCGGGCACCAGCTTCAACGCGCTGCAC
CGCGGCGAGTTGACCGCTCT

Product: iron ABC transporter

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTVQTTNPDPARDIVGAYRRRSAKRVALVCLAAVALGAMIVIDIITGPAELGFLRTLHVILDPSIATAKEAVIIWDLRLP
VALMAVVVGAMLGVAGAEMQTILNNPLADPFTLGLSSAASFGAALAIVLGFSVIPAVGGLLVTVNAFMFSLFASLALFAF
TKLRGVTPEAMILVGIAMLFSFNALLAFLQYGASELELAQLIFWQMGSLARATWAKVGICLVVLAIVLPYFLSRSWALTA
LRMGEDKAAALGVNVALLRLAVLAGVSLLSAVAVSFVGAIAFVGLVGPHIARLIVGEDQRGFLPLSALMGALILSATSIV
SKAITPGIVYPIGMITSLIGIPFFVSLILSQRKRHW

Sequences:

>Translated_356_residues
MTVQTTNPDPARDIVGAYRRRSAKRVALVCLAAVALGAMIVIDIITGPAELGFLRTLHVILDPSIATAKEAVIIWDLRLP
VALMAVVVGAMLGVAGAEMQTILNNPLADPFTLGLSSAASFGAALAIVLGFSVIPAVGGLLVTVNAFMFSLFASLALFAF
TKLRGVTPEAMILVGIAMLFSFNALLAFLQYGASELELAQLIFWQMGSLARATWAKVGICLVVLAIVLPYFLSRSWALTA
LRMGEDKAAALGVNVALLRLAVLAGVSLLSAVAVSFVGAIAFVGLVGPHIARLIVGEDQRGFLPLSALMGALILSATSIV
SKAITPGIVYPIGMITSLIGIPFFVSLILSQRKRHW
>Mature_355_residues
TVQTTNPDPARDIVGAYRRRSAKRVALVCLAAVALGAMIVIDIITGPAELGFLRTLHVILDPSIATAKEAVIIWDLRLPV
ALMAVVVGAMLGVAGAEMQTILNNPLADPFTLGLSSAASFGAALAIVLGFSVIPAVGGLLVTVNAFMFSLFASLALFAFT
KLRGVTPEAMILVGIAMLFSFNALLAFLQYGASELELAQLIFWQMGSLARATWAKVGICLVVLAIVLPYFLSRSWALTAL
RMGEDKAAALGVNVALLRLAVLAGVSLLSAVAVSFVGAIAFVGLVGPHIARLIVGEDQRGFLPLSALMGALILSATSIVS
KAITPGIVYPIGMITSLIGIPFFVSLILSQRKRHW

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=284, Percent_Identity=32.3943661971831, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=32.404181184669, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786347, Length=295, Percent_Identity=33.8983050847458, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786805, Length=292, Percent_Identity=35.6164383561644, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790741, Length=290, Percent_Identity=34.8275862068965, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786804, Length=286, Percent_Identity=33.5664335664336, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37336; Mature: 37205

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQTTNPDPARDIVGAYRRRSAKRVALVCLAAVALGAMIVIDIITGPAELGFLRTLHVI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LDPSIATAKEAVIIWDLRLPVALMAVVVGAMLGVAGAEMQTILNNPLADPFTLGLSSAAS
HCCCHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHH
FGAALAIVLGFSVIPAVGGLLVTVNAFMFSLFASLALFAFTKLRGVTPEAMILVGIAMLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SFNALLAFLQYGASELELAQLIFWQMGSLARATWAKVGICLVVLAIVLPYFLSRSWALTA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LRMGEDKAAALGVNVALLRLAVLAGVSLLSAVAVSFVGAIAFVGLVGPHIARLIVGEDQR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GFLPLSALMGALILSATSIVSKAITPGIVYPIGMITSLIGIPFFVSLILSQRKRHW
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVQTTNPDPARDIVGAYRRRSAKRVALVCLAAVALGAMIVIDIITGPAELGFLRTLHVI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LDPSIATAKEAVIIWDLRLPVALMAVVVGAMLGVAGAEMQTILNNPLADPFTLGLSSAAS
HCCCHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHH
FGAALAIVLGFSVIPAVGGLLVTVNAFMFSLFASLALFAFTKLRGVTPEAMILVGIAMLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SFNALLAFLQYGASELELAQLIFWQMGSLARATWAKVGICLVVLAIVLPYFLSRSWALTA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LRMGEDKAAALGVNVALLRLAVLAGVSLLSAVAVSFVGAIAFVGLVGPHIARLIVGEDQR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GFLPLSALMGALILSATSIVSKAITPGIVYPIGMITSLIGIPFFVSLILSQRKRHW
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]