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The map label for this gene is fabZ

Identifier: 110679825

GI number: 110679825

Start: 2478861

End: 2479319

Strand: Direct

Name: fabZ

Synonym: RD1_2595

Alternate gene names: 110679825

Gene position: 2478861-2479319 (Clockwise)

Preceding gene: 110679824

Following gene: 110679826

Centisome position: 59.98

GC content: 56.64

Gene sequence:

>459_bases
ATGTCGACCAGCCAGACCAGCGCGGATATTCAACTGATCCAGCGTATCCTACCTCATCGCTATCCCTTTCTGCTTGTCGA
CAAGGTGGTGGAAATCGACGGCACCACATCCGCCCTCGGCATCAAGAATGTCACCATGAATGAGCCGCATTTTCAGGGCC
ATTTCCCGGGAATGCCCATCATGCCGGGCGTTACGATCGTGGAAGCCATGGCACAAACGGCTGCGGTCATGGTCGGTGTG
ACGCTGGAAATGGCGGATAAGGAAATGAAAGTGTATTTCATGGCAATCGACAAGGCGAAGTTCCGTCGCAAGGTCATCCC
CGGTGATGTGCTTGAGATGCGGCTGAACACCCTGCGTGGCAAACCCGGCGGCAAAGTCTGGCGCTTTGGCGGTGTCGCAT
CGGTTGAGGGCGAGATGGCCGCCGAAGTCGAGTTTACCGCCATGATGGACATGGGCTGA

Upstream 100 bases:

>100_bases
TCGCCCCCGAGCCGCAATAAGCGAAGTGGTCAACCTTGCTCCGGGACGTGGGAGTTGGTAGTCAGGTCGCCAAGCCCTTG
AAGACTAAAGGACCTCCGAG

Downstream 100 bases:

>100_bases
TCGTTGATGGGCAACATTCACCCCAGTGCTGTCATCGACCCCGGCGCGCAGATCGACCCGAGCGCAAGGGTCGGCCCGTT
TTGTGTGGTGGGTGCGCAGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MSTSQTSADIQLIQRILPHRYPFLLVDKVVEIDGTTSALGIKNVTMNEPHFQGHFPGMPIMPGVTIVEAMAQTAAVMVGV
TLEMADKEMKVYFMAIDKAKFRRKVIPGDVLEMRLNTLRGKPGGKVWRFGGVASVEGEMAAEVEFTAMMDMG

Sequences:

>Translated_152_residues
MSTSQTSADIQLIQRILPHRYPFLLVDKVVEIDGTTSALGIKNVTMNEPHFQGHFPGMPIMPGVTIVEAMAQTAAVMVGV
TLEMADKEMKVYFMAIDKAKFRRKVIPGDVLEMRLNTLRGKPGGKVWRFGGVASVEGEMAAEVEFTAMMDMG
>Mature_151_residues
STSQTSADIQLIQRILPHRYPFLLVDKVVEIDGTTSALGIKNVTMNEPHFQGHFPGMPIMPGVTIVEAMAQTAAVMVGVT
LEMADKEMKVYFMAIDKAKFRRKVIPGDVLEMRLNTLRGKPGGKVWRFGGVASVEGEMAAEVEFTAMMDMG

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=142, Percent_Identity=42.2535211267606, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_ROSDO (Q166E7)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682832.1
- ProteinModelPortal:   Q166E7
- SMR:   Q166E7
- STRING:   Q166E7
- GeneID:   4195034
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2595
- NMPDR:   fig|375451.6.peg.2411
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KNIRADY
- ProtClustDB:   PRK00006
- BioCyc:   RDEN375451:RD1_2595-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16705; Mature: 16574

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
9.2 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
8.6 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSQTSADIQLIQRILPHRYPFLLVDKVVEIDGTTSALGIKNVTMNEPHFQGHFPGMPI
CCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEECCCCCCCCCCCCCCCCCCC
MPGVTIVEAMAQTAAVMVGVTLEMADKEMKVYFMAIDKAKFRRKVIPGDVLEMRLNTLRG
CCCHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEEECHHHHHHHCCCCHHHHHHHHHHCC
KPGGKVWRFGGVASVEGEMAAEVEFTAMMDMG
CCCCCEEEECCEEECCCCEEEEEEEEEEECCC
>Mature Secondary Structure 
STSQTSADIQLIQRILPHRYPFLLVDKVVEIDGTTSALGIKNVTMNEPHFQGHFPGMPI
CCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEECCCCCCCCCCCCCCCCCCC
MPGVTIVEAMAQTAAVMVGVTLEMADKEMKVYFMAIDKAKFRRKVIPGDVLEMRLNTLRG
CCCHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEEECHHHHHHHCCCCHHHHHHHHHHCC
KPGGKVWRFGGVASVEGEMAAEVEFTAMMDMG
CCCCCEEEECCEEECCCCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA