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The map label for this gene is tas [H]

Identifier: 110679757

GI number: 110679757

Start: 2407223

End: 2408266

Strand: Direct

Name: tas [H]

Synonym: RD1_2520

Alternate gene names: 110679757

Gene position: 2407223-2408266 (Clockwise)

Preceding gene: 110679752

Following gene: 110679758

Centisome position: 58.24

GC content: 57.28

Gene sequence:

>1044_bases
ATGAAGATGAATCCACTGGGCCACTCGGGAATTGAGGTATCAGAGTTCTGTCTGGGGTCCATGACCTGGGGGACGCAAAA
TAACGCAGAAGAGGCGCATGATCAGATTGACCGCGCGTTGGATGCAGGCATTAATTTCATCGACACCGCCGAGATGTACC
CTGTGAACCCGGTTTCGGAGGAAACAATCGGTCGCACGGAACGCATCATCGGCCTGTGGTTTGAGCGTGATGAGCGGCGC
GAGGATGTGATCCTTGCCACCAAACACTCCGGTGAGGGGTTGGCATCCGTTCGCGAAGGCGCACCCATTTCATCCGCGAC
GATTGCCGAGGCGGTTGAGGGTTCGCTGCGCCGTCTGAAAACCGATTACATCGACCTCTATCAGTTTCACTGGCCCAACC
GCGGCAGCTATATGTTTCGCAAGAACTGGGCCTATGATCCTTCCTCGCAGTTGATGCTGGACACGAAACATCACATGGAA
GACGCGCTGGACGCGCTGCAAAAGCAGGTGAAGCGCGGGACGATCCGCGCCTTTGGGCTCAGCAATGAAAGCGCATGGGG
CACGACGAAATGGATCGAGACGGCCGCGCGCGTTGGCGGGCCACGGGTTGCTTCCGTGCAAAACGAGTATTCGTTGCTGT
GCCGCCTTTATGACACCGACATGGCCGAGATGTCGCTTCAGGAAGATGTGCCGCTGCTGGCCTTTTCCCCCTTGGCGGCC
GGTTTGCTGACGGGGAAATATCAGGGCGGCGCCGTGCCTGCGGGGTCGCGGATGTCGTTGAGCAAGGATCTGGGCGGGCG
CAAGACCGCGCGTGCGTTTGAAGCTGTTCAGGCATATCTCGAAATTGCGCAAAAACATGATCTGGACCCTACGCAGATGG
CATTGGCATGGTGCAAAACCCGACCCTTTATGGGTTCCATCATTTTTGGTGCGACGACACTGGCGCAGCTTGATGTCTGT
CTCGGTGCGATTGATCTGGAATTATCTGCGGAGGTTGTGGCGGATATTGATGCAGCCCATCGCGCGCATCCCATGCCCTA
CTAA

Upstream 100 bases:

>100_bases
CAGGATGCAAAACAGTCAGTGTGTATAGAGAGGTTGTAAACCACCTTGCGGTTATCGCAGCCCTGATTACTGTGAGGCGA
GCAGGAAAAGGGAATACACG

Downstream 100 bases:

>100_bases
CCCTTTACTTATACGGTATCCTTTGCGGCAGAATCGGATTATCCCGGCTTTGCCGGGCCTTCCGTTCGCCCGTGTTGCGC
GTAAGAAAGGGATGACTGAT

Product: oxidoreductase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKMNPLGHSGIEVSEFCLGSMTWGTQNNAEEAHDQIDRALDAGINFIDTAEMYPVNPVSEETIGRTERIIGLWFERDERR
EDVILATKHSGEGLASVREGAPISSATIAEAVEGSLRRLKTDYIDLYQFHWPNRGSYMFRKNWAYDPSSQLMLDTKHHME
DALDALQKQVKRGTIRAFGLSNESAWGTTKWIETAARVGGPRVASVQNEYSLLCRLYDTDMAEMSLQEDVPLLAFSPLAA
GLLTGKYQGGAVPAGSRMSLSKDLGGRKTARAFEAVQAYLEIAQKHDLDPTQMALAWCKTRPFMGSIIFGATTLAQLDVC
LGAIDLELSAEVVADIDAAHRAHPMPY

Sequences:

>Translated_347_residues
MKMNPLGHSGIEVSEFCLGSMTWGTQNNAEEAHDQIDRALDAGINFIDTAEMYPVNPVSEETIGRTERIIGLWFERDERR
EDVILATKHSGEGLASVREGAPISSATIAEAVEGSLRRLKTDYIDLYQFHWPNRGSYMFRKNWAYDPSSQLMLDTKHHME
DALDALQKQVKRGTIRAFGLSNESAWGTTKWIETAARVGGPRVASVQNEYSLLCRLYDTDMAEMSLQEDVPLLAFSPLAA
GLLTGKYQGGAVPAGSRMSLSKDLGGRKTARAFEAVQAYLEIAQKHDLDPTQMALAWCKTRPFMGSIIFGATTLAQLDVC
LGAIDLELSAEVVADIDAAHRAHPMPY
>Mature_347_residues
MKMNPLGHSGIEVSEFCLGSMTWGTQNNAEEAHDQIDRALDAGINFIDTAEMYPVNPVSEETIGRTERIIGLWFERDERR
EDVILATKHSGEGLASVREGAPISSATIAEAVEGSLRRLKTDYIDLYQFHWPNRGSYMFRKNWAYDPSSQLMLDTKHHME
DALDALQKQVKRGTIRAFGLSNESAWGTTKWIETAARVGGPRVASVQNEYSLLCRLYDTDMAEMSLQEDVPLLAFSPLAA
GLLTGKYQGGAVPAGSRMSLSKDLGGRKTARAFEAVQAYLEIAQKHDLDPTQMALAWCKTRPFMGSIIFGATTLAQLDVC
LGAIDLELSAEVVADIDAAHRAHPMPY

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=357, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI27436962, Length=357, Percent_Identity=29.1316526610644, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI27436966, Length=357, Percent_Identity=29.1316526610644, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI27436969, Length=355, Percent_Identity=28.4507042253521, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4504825, Length=355, Percent_Identity=28.4507042253521, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI27436971, Length=363, Percent_Identity=28.9256198347107, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=42.3295454545455, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI87081735, Length=353, Percent_Identity=30.5949008498584, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788070, Length=348, Percent_Identity=25.5747126436782, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=28.0346820809249, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788081, Length=352, Percent_Identity=27.8409090909091, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323998, Length=345, Percent_Identity=23.1884057971014, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=328, Percent_Identity=21.9512195121951, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319951, Length=336, Percent_Identity=23.5119047619048, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644950, Length=325, Percent_Identity=24.9230769230769, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38302; Mature: 38302

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMNPLGHSGIEVSEFCLGSMTWGTQNNAEEAHDQIDRALDAGINFIDTAEMYPVNPVSE
CCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCH
ETIGRTERIIGLWFERDERREDVILATKHSGEGLASVREGAPISSATIAEAVEGSLRRLK
HHHCCHHHHEEEEECCCCCCCCEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
TDYIDLYQFHWPNRGSYMFRKNWAYDPSSQLMLDTKHHMEDALDALQKQVKRGTIRAFGL
HHHHHHHEEECCCCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCEEEEEC
SNESAWGTTKWIETAARVGGPRVASVQNEYSLLCRLYDTDMAEMSLQEDVPLLAFSPLAA
CCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEHHHHH
GLLTGKYQGGAVPAGSRMSLSKDLGGRKTARAFEAVQAYLEIAQKHDLDPTQMALAWCKT
HHHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
RPFMGSIIFGATTLAQLDVCLGAIDLELSAEVVADIDAAHRAHPMPY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKMNPLGHSGIEVSEFCLGSMTWGTQNNAEEAHDQIDRALDAGINFIDTAEMYPVNPVSE
CCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCH
ETIGRTERIIGLWFERDERREDVILATKHSGEGLASVREGAPISSATIAEAVEGSLRRLK
HHHCCHHHHEEEEECCCCCCCCEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
TDYIDLYQFHWPNRGSYMFRKNWAYDPSSQLMLDTKHHMEDALDALQKQVKRGTIRAFGL
HHHHHHHEEECCCCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCEEEEEC
SNESAWGTTKWIETAARVGGPRVASVQNEYSLLCRLYDTDMAEMSLQEDVPLLAFSPLAA
CCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEHHHHH
GLLTGKYQGGAVPAGSRMSLSKDLGGRKTARAFEAVQAYLEIAQKHDLDPTQMALAWCKT
HHHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
RPFMGSIIFGATTLAQLDVCLGAIDLELSAEVVADIDAAHRAHPMPY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]