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The map label for this gene is ptxB [H]

Identifier: 110679651

GI number: 110679651

Start: 2290535

End: 2291446

Strand: Reverse

Name: ptxB [H]

Synonym: RD1_2402

Alternate gene names: 110679651

Gene position: 2291446-2290535 (Counterclockwise)

Preceding gene: 110679652

Following gene: 110679650

Centisome position: 55.44

GC content: 59.21

Gene sequence:

>912_bases
ATGAAAAAGACCCTCGCACTGGCGCTTGCCGCCTCCACAGCCCTCAGCACAGGAGCTTTTGCGCAAGAGATCACCGAGTT
CCGCATCGGGATCCTCGGCGGTGAAAACGCGCAGGACCGGATGAACAGCTATCAGTGCCTTGCCGATTACACGACCGAAG
CGCTCGGCGTCGAAACCAAGCTTTTTGCGCCGGCTGACTACAACGGCGTGATTCAGGGCCTGCTGGGCGGTACCATCGAT
ATGGCGTGGCTGGGGGCCTCTGCCTATGCCGCAACCTACCTGCAGGACCCGGAAGCGGTTAAGCCTGTGCTGATCAAGGT
GAATGTCGACGGCTCCATCGGCTACCACTCCATCGGTTTTGCCCGCGTGGACAGTGGCATCACCTCGCTGGATGACATGA
AAGGAAAGGTCTTTGGTTTTGGCGACCCGAACTCGACCTCCGGGTACCTGATCCCTTCCATCGAAATCCCGCAGTATAAG
GACGGCATGACCATGGAAAGCGGTGAGTACTTCGGTGAAGTCAAATTCACGGGCGGCCACGAGCAGACCATCGTTGCGGT
GAACAACGGCGACATTGATGGCGGCGTCACATGGGCCGATGGTCAGGGCAACTGGGAAGACGGCTACAACTCCGGCGCGC
TGCGCAAGGCGGTGGACGCGGGGCTCGTTGACATGAACGACATGGTTCAGATCTGGAAATCCAACGTCATCCCGGAAGGT
CCGGTCGTGCTGCGCAAGGCCCTTCCGGCACAAGTGCGCGAAACCATGACCGCATTGGTTGACGGCCTGCATGAACGTGA
CCCGGACTGTGCTTATGGTGTGGCTGCAGGCGACACGCTGGGCTTTCAGCCCGTGACACATGACACCTACATTTCCATCG
TCGAAGCGCGCAAAGCGAAAATCGGCGGCTAA

Upstream 100 bases:

>100_bases
GCCTGAGCCGGTTTCACCCTGCGCATCTGCTGCAGGCCACATAAATCAACCCGCCCCGAAAAGCCGCATATCGGCAGGGC
AGACAACGACGGAGATACCG

Downstream 100 bases:

>100_bases
GCCCTTTTCATCACGCGTCCGGCAGGCCCTCGGGCCTGTCGGTATTTTTGTATCCGGGGGCAGCATGGCTGACATTTCTA
CAGGCGGCGCGCCGCAAACC

Product: phosphonate ABC transporter, periplasmic phosphonate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKKTLALALAASTALSTGAFAQEITEFRIGILGGENAQDRMNSYQCLADYTTEALGVETKLFAPADYNGVIQGLLGGTID
MAWLGASAYAATYLQDPEAVKPVLIKVNVDGSIGYHSIGFARVDSGITSLDDMKGKVFGFGDPNSTSGYLIPSIEIPQYK
DGMTMESGEYFGEVKFTGGHEQTIVAVNNGDIDGGVTWADGQGNWEDGYNSGALRKAVDAGLVDMNDMVQIWKSNVIPEG
PVVLRKALPAQVRETMTALVDGLHERDPDCAYGVAAGDTLGFQPVTHDTYISIVEARKAKIGG

Sequences:

>Translated_303_residues
MKKTLALALAASTALSTGAFAQEITEFRIGILGGENAQDRMNSYQCLADYTTEALGVETKLFAPADYNGVIQGLLGGTID
MAWLGASAYAATYLQDPEAVKPVLIKVNVDGSIGYHSIGFARVDSGITSLDDMKGKVFGFGDPNSTSGYLIPSIEIPQYK
DGMTMESGEYFGEVKFTGGHEQTIVAVNNGDIDGGVTWADGQGNWEDGYNSGALRKAVDAGLVDMNDMVQIWKSNVIPEG
PVVLRKALPAQVRETMTALVDGLHERDPDCAYGVAAGDTLGFQPVTHDTYISIVEARKAKIGG
>Mature_303_residues
MKKTLALALAASTALSTGAFAQEITEFRIGILGGENAQDRMNSYQCLADYTTEALGVETKLFAPADYNGVIQGLLGGTID
MAWLGASAYAATYLQDPEAVKPVLIKVNVDGSIGYHSIGFARVDSGITSLDDMKGKVFGFGDPNSTSGYLIPSIEIPQYK
DGMTMESGEYFGEVKFTGGHEQTIVAVNNGDIDGGVTWADGQGNWEDGYNSGALRKAVDAGLVDMNDMVQIWKSNVIPEG
PVVLRKALPAQVRETMTALVDGLHERDPDCAYGVAAGDTLGFQPVTHDTYISIVEARKAKIGG

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=295, Percent_Identity=27.4576271186441, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 32162; Mature: 32162

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLALALAASTALSTGAFAQEITEFRIGILGGENAQDRMNSYQCLADYTTEALGVETK
CCCCEEEEEHHHHHHHCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEE
LFAPADYNGVIQGLLGGTIDMAWLGASAYAATYLQDPEAVKPVLIKVNVDGSIGYHSIGF
EECCCCCHHHHHHHHCCCEEHHHHCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCH
ARVDSGITSLDDMKGKVFGFGDPNSTSGYLIPSIEIPQYKDGMTMESGEYFGEVKFTGGH
HHHCCCCCCHHHCCCCEEECCCCCCCCCEEEECCCCCCCCCCCEEECCCEEEEEEEECCC
EQTIVAVNNGDIDGGVTWADGQGNWEDGYNSGALRKAVDAGLVDMNDMVQIWKSNVIPEG
CEEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCC
PVVLRKALPAQVRETMTALVDGLHERDPDCAYGVAAGDTLGFQPVTHDTYISIVEARKAK
HHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHC
IGG
CCC
>Mature Secondary Structure
MKKTLALALAASTALSTGAFAQEITEFRIGILGGENAQDRMNSYQCLADYTTEALGVETK
CCCCEEEEEHHHHHHHCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEE
LFAPADYNGVIQGLLGGTIDMAWLGASAYAATYLQDPEAVKPVLIKVNVDGSIGYHSIGF
EECCCCCHHHHHHHHCCCEEHHHHCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCH
ARVDSGITSLDDMKGKVFGFGDPNSTSGYLIPSIEIPQYKDGMTMESGEYFGEVKFTGGH
HHHCCCCCCHHHCCCCEEECCCCCCCCCEEEECCCCCCCCCCCEEECCCEEEEEEEECCC
EQTIVAVNNGDIDGGVTWADGQGNWEDGYNSGALRKAVDAGLVDMNDMVQIWKSNVIPEG
CEEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCC
PVVLRKALPAQVRETMTALVDGLHERDPDCAYGVAAGDTLGFQPVTHDTYISIVEARKAK
HHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHC
IGG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]