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The map label for this gene is aglA [H]

Identifier: 110679581

GI number: 110679581

Start: 2219498

End: 2221150

Strand: Direct

Name: aglA [H]

Synonym: RD1_2326

Alternate gene names: 110679581

Gene position: 2219498-2221150 (Clockwise)

Preceding gene: 110679580

Following gene: 110679582

Centisome position: 53.7

GC content: 59.04

Gene sequence:

>1653_bases
ATGGCCAAGATGGAACACAATCTGCACCTGAGTGCAGTCGACAAGGACTGGTGGCGCGGTGCCGTCATCTACCAGATTTA
TCCGCGCAGTTTTCAGGACAGCAACGGTGACGGGATCGGCGATTTGCTGGGGATCGCGCAGCGGATGGAATATGTGGCCT
CGCTCGGGGTCGATGCAATCTGGATTTCGCCGTTCTTTACCTCGCCGATGAAAGACTTCGGTTATGATGTCAGCGATTAC
TGCGATGTTGACCCGATGTTTGGCACGCTCGCGGATTTTGATGTGCTGGTCGAGGCGGCGCATCACCACGGGCTGAAGGT
GATGATTGATCTGGTGCTCAGCCACACCTCGGACCAGCACCCGTGGTTCATCGAAAGCAAGTCGAGCCGCAACAACCCCA
AAGCGGATTGGTATGTCTGGGCCGACCCCAAACCGGACGGCACACCGCCCAACAACTGGCTGTCGATCTTTGGCGGGCCT
GCGTGGCAGTGGCATGCGGGGCGTCAGCAGTATTACCTGCACAACTTCCTGATCGAACAACCCGACCTGAATTTCCACAA
CACGGATGTGCAGGACGCGCTTCTGGATGTGACACGGTTCTGGCTGGATCGGGGGGTGGATGGCTTCCGGCTTGATACGA
TCAACTTTTACTATGCGGATAAAGACCTGCGCGACAATCCGGCCCTGCCGCCCGAGCAGCGCAATGATACCATCGCGCCC
TCGGTCAATCCCTACAACCATCAGGAACATCTCTACTCCAAGAACCAGCCTGAAAATATCGCCTTTCTCAAACGCTTCCG
GGCGCTGTTGGATGAATACCCGGCGGCGGCCTGTGTCGGCGAGGTGGGCGATGCGCAGCGGGGTCTGGAACTGTTGGGGG
CTTACACCTCGGGGCCTGAAATGGTGCATATGTGCTATGCGTTCGAGTTTCTGTCCAAGACTAAACTCGATGCCGCGCGC
GTCGCCGAAGTCTTTGGCCAGCTGGATATGGTCGGGCCGGACGGCTGGCCGTGCTGGGCGTTTTCCAACCACGATGTGAT
GCGCCATTCCACCAGATGGGAGCTGTCACCGGCTGCTGAACGGCTGTTTGCGACCCTGCTGATGTGTCTGCGCGGGTCGG
TGTGCCTGTATCAGGGGGAGGAACTGGGCCTGTCTGAGGCCGATGTCGCCTTTGAAGACCTGCAAGACCCCTATGGCATC
ACCTTCTGGCCTGATTTCAAGGGCCGCGATGGGTGCCGCACGCCTATGGTCTGGGAAATGTCCAACCAGAACGGGGGGTT
CTCCGAAGGGTTTCCGTGGTTGCCGGTCAGCCATGAACACCTCAACCACGCGGTGTCAGTGCAGGAGTCCGAACCCGGCT
CCTTGCTGCATCACTACCGAAATGCGATTGCATTTCGCGCCGAGCACCCTGCGCTGACCAAAGGGTCACACGACGGGGTG
CAGGCCAACGGCGATGTGTTGCACTTCACCCGCGAATATGACGGTCAGACGCTCTATTGCGCGTTCAACATGTCGGACAC
GCCGTCGTTGCACCAGATGCCCAAAGGCACCTGGCAGGTGATCGGACAGGAACTGGGCAGCGCCAGCGCGTCTCCCCAGG
GCCAATTGCACTTTGGGCCGTGGCAGGTCTGCCTCGCGAAGAAACAAGACTAA

Upstream 100 bases:

>100_bases
TTATCTCGATCGCTGTGCCGCTGATCGTGTTTTTCACAATGCAACGCTATCTGGTGCGCGGTCTGCTGGCCGGCTCCGTC
AAGTAGGAAAGAACTGCTCC

Downstream 100 bases:

>100_bases
CCCGCGTCTTGGGAGGGACGTAAGATATGGCAAATCTCAATCTGACAGACGTTGGCAAGGCCTATGGGGGCACTGTTGAG
GTGCTGAAAAACATCAACCT

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MAKMEHNLHLSAVDKDWWRGAVIYQIYPRSFQDSNGDGIGDLLGIAQRMEYVASLGVDAIWISPFFTSPMKDFGYDVSDY
CDVDPMFGTLADFDVLVEAAHHHGLKVMIDLVLSHTSDQHPWFIESKSSRNNPKADWYVWADPKPDGTPPNNWLSIFGGP
AWQWHAGRQQYYLHNFLIEQPDLNFHNTDVQDALLDVTRFWLDRGVDGFRLDTINFYYADKDLRDNPALPPEQRNDTIAP
SVNPYNHQEHLYSKNQPENIAFLKRFRALLDEYPAAACVGEVGDAQRGLELLGAYTSGPEMVHMCYAFEFLSKTKLDAAR
VAEVFGQLDMVGPDGWPCWAFSNHDVMRHSTRWELSPAAERLFATLLMCLRGSVCLYQGEELGLSEADVAFEDLQDPYGI
TFWPDFKGRDGCRTPMVWEMSNQNGGFSEGFPWLPVSHEHLNHAVSVQESEPGSLLHHYRNAIAFRAEHPALTKGSHDGV
QANGDVLHFTREYDGQTLYCAFNMSDTPSLHQMPKGTWQVIGQELGSASASPQGQLHFGPWQVCLAKKQD

Sequences:

>Translated_550_residues
MAKMEHNLHLSAVDKDWWRGAVIYQIYPRSFQDSNGDGIGDLLGIAQRMEYVASLGVDAIWISPFFTSPMKDFGYDVSDY
CDVDPMFGTLADFDVLVEAAHHHGLKVMIDLVLSHTSDQHPWFIESKSSRNNPKADWYVWADPKPDGTPPNNWLSIFGGP
AWQWHAGRQQYYLHNFLIEQPDLNFHNTDVQDALLDVTRFWLDRGVDGFRLDTINFYYADKDLRDNPALPPEQRNDTIAP
SVNPYNHQEHLYSKNQPENIAFLKRFRALLDEYPAAACVGEVGDAQRGLELLGAYTSGPEMVHMCYAFEFLSKTKLDAAR
VAEVFGQLDMVGPDGWPCWAFSNHDVMRHSTRWELSPAAERLFATLLMCLRGSVCLYQGEELGLSEADVAFEDLQDPYGI
TFWPDFKGRDGCRTPMVWEMSNQNGGFSEGFPWLPVSHEHLNHAVSVQESEPGSLLHHYRNAIAFRAEHPALTKGSHDGV
QANGDVLHFTREYDGQTLYCAFNMSDTPSLHQMPKGTWQVIGQELGSASASPQGQLHFGPWQVCLAKKQD
>Mature_549_residues
AKMEHNLHLSAVDKDWWRGAVIYQIYPRSFQDSNGDGIGDLLGIAQRMEYVASLGVDAIWISPFFTSPMKDFGYDVSDYC
DVDPMFGTLADFDVLVEAAHHHGLKVMIDLVLSHTSDQHPWFIESKSSRNNPKADWYVWADPKPDGTPPNNWLSIFGGPA
WQWHAGRQQYYLHNFLIEQPDLNFHNTDVQDALLDVTRFWLDRGVDGFRLDTINFYYADKDLRDNPALPPEQRNDTIAPS
VNPYNHQEHLYSKNQPENIAFLKRFRALLDEYPAAACVGEVGDAQRGLELLGAYTSGPEMVHMCYAFEFLSKTKLDAARV
AEVFGQLDMVGPDGWPCWAFSNHDVMRHSTRWELSPAAERLFATLLMCLRGSVCLYQGEELGLSEADVAFEDLQDPYGIT
FWPDFKGRDGCRTPMVWEMSNQNGGFSEGFPWLPVSHEHLNHAVSVQESEPGSLLHHYRNAIAFRAEHPALTKGSHDGVQ
ANGDVLHFTREYDGQTLYCAFNMSDTPSLHQMPKGTWQVIGQELGSASASPQGQLHFGPWQVCLAKKQD

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=537, Percent_Identity=34.6368715083799, Blast_Score=290, Evalue=4e-78,
Organism=Escherichia coli, GI1790687, Length=551, Percent_Identity=34.1197822141561, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1786604, Length=483, Percent_Identity=21.9461697722567, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32565753, Length=516, Percent_Identity=24.2248062015504, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI25147709, Length=511, Percent_Identity=25.6360078277886, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321726, Length=550, Percent_Identity=33.4545454545455, Blast_Score=272, Evalue=8e-74,
Organism=Saccharomyces cerevisiae, GI6321731, Length=553, Percent_Identity=33.2730560578662, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6319776, Length=553, Percent_Identity=33.2730560578662, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6322245, Length=556, Percent_Identity=31.1151079136691, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6322241, Length=554, Percent_Identity=32.6714801444043, Blast_Score=266, Evalue=9e-72,
Organism=Saccharomyces cerevisiae, GI6322021, Length=554, Percent_Identity=32.6714801444043, Blast_Score=266, Evalue=9e-72,
Organism=Saccharomyces cerevisiae, GI6324416, Length=550, Percent_Identity=33.4545454545455, Blast_Score=265, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24583747, Length=516, Percent_Identity=37.2093023255814, Blast_Score=314, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24583749, Length=516, Percent_Identity=37.2093023255814, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24586587, Length=477, Percent_Identity=37.1069182389937, Blast_Score=311, Evalue=8e-85,
Organism=Drosophila melanogaster, GI24583745, Length=516, Percent_Identity=38.3720930232558, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24586591, Length=510, Percent_Identity=36.2745098039216, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24586599, Length=561, Percent_Identity=33.1550802139037, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI45549022, Length=545, Percent_Identity=33.2110091743119, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24586589, Length=511, Percent_Identity=36.5949119373777, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24586593, Length=519, Percent_Identity=35.0674373795761, Blast_Score=293, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24586597, Length=485, Percent_Identity=34.4329896907216, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI221330053, Length=529, Percent_Identity=33.0812854442344, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI281360393, Length=461, Percent_Identity=31.8872017353579, Blast_Score=214, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 62224; Mature: 62093

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKMEHNLHLSAVDKDWWRGAVIYQIYPRSFQDSNGDGIGDLLGIAQRMEYVASLGVDAI
CCCCCCCEEEEECCCCHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
WISPFFTSPMKDFGYDVSDYCDVDPMFGTLADFDVLVEAAHHHGLKVMIDLVLSHTSDQH
EECCHHCCCHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
PWFIESKSSRNNPKADWYVWADPKPDGTPPNNWLSIFGGPAWQWHAGRQQYYLHNFLIEQ
CEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCEEECCCCCCEEHHHHEECC
PDLNFHNTDVQDALLDVTRFWLDRGVDGFRLDTINFYYADKDLRDNPALPPEQRNDTIAP
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
SVNPYNHQEHLYSKNQPENIAFLKRFRALLDEYPAAACVGEVGDAQRGLELLGAYTSGPE
CCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCCCHH
MVHMCYAFEFLSKTKLDAARVAEVFGQLDMVGPDGWPCWAFSNHDVMRHSTRWELSPAAE
HHHHHHHHHHHHHHCCHHHHHHHHHHCEEECCCCCCEEEEECCCCHHHCCCCCCCCHHHH
RLFATLLMCLRGSVCLYQGEELGLSEADVAFEDLQDPYGITFWPDFKGRDGCRTPMVWEM
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEEE
SNQNGGFSEGFPWLPVSHEHLNHAVSVQESEPGSLLHHYRNAIAFRAEHPALTKGSHDGV
CCCCCCCCCCCCCCCCCHHHHCCEEEECCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCC
QANGDVLHFTREYDGQTLYCAFNMSDTPSLHQMPKGTWQVIGQELGSASASPQGQLHFGP
CCCCCEEEEEEECCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCEECCH
WQVCLAKKQD
HHEEEECCCC
>Mature Secondary Structure 
AKMEHNLHLSAVDKDWWRGAVIYQIYPRSFQDSNGDGIGDLLGIAQRMEYVASLGVDAI
CCCCCCEEEEECCCCHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
WISPFFTSPMKDFGYDVSDYCDVDPMFGTLADFDVLVEAAHHHGLKVMIDLVLSHTSDQH
EECCHHCCCHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
PWFIESKSSRNNPKADWYVWADPKPDGTPPNNWLSIFGGPAWQWHAGRQQYYLHNFLIEQ
CEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCEEECCCCCCEEHHHHEECC
PDLNFHNTDVQDALLDVTRFWLDRGVDGFRLDTINFYYADKDLRDNPALPPEQRNDTIAP
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
SVNPYNHQEHLYSKNQPENIAFLKRFRALLDEYPAAACVGEVGDAQRGLELLGAYTSGPE
CCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCCCHH
MVHMCYAFEFLSKTKLDAARVAEVFGQLDMVGPDGWPCWAFSNHDVMRHSTRWELSPAAE
HHHHHHHHHHHHHHCCHHHHHHHHHHCEEECCCCCCEEEEECCCCHHHCCCCCCCCHHHH
RLFATLLMCLRGSVCLYQGEELGLSEADVAFEDLQDPYGITFWPDFKGRDGCRTPMVWEM
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEEE
SNQNGGFSEGFPWLPVSHEHLNHAVSVQESEPGSLLHHYRNAIAFRAEHPALTKGSHDGV
CCCCCCCCCCCCCCCCCHHHHCCEEEECCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCC
QANGDVLHFTREYDGQTLYCAFNMSDTPSLHQMPKGTWQVIGQELGSASASPQGQLHFGP
CCCCCEEEEEEECCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCEECCH
WQVCLAKKQD
HHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]