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The map label for this gene is dctM [H]

Identifier: 110679573

GI number: 110679573

Start: 2209057

End: 2210346

Strand: Direct

Name: dctM [H]

Synonym: RD1_2314

Alternate gene names: 110679573

Gene position: 2209057-2210346 (Clockwise)

Preceding gene: 110679572

Following gene: 110679574

Centisome position: 53.45

GC content: 58.76

Gene sequence:

>1290_bases
ATGCTGGTCTGGTTTCTTCCGCTGTTTTTGCTGTTCCTGCTGATCGGGTTGCCGGTATTTTTCGGCCTGCTCGCAGCGCC
GGGGCTACTGCTGTGGCTCAACGGTCAGGAAAAAGACATCACGCTGCTGTATCGCAATGTTTATAACGGGATAGACAGCT
TTCCCCTGATGGCGATCCCCTTCTTCATGCTGGCCGGAGAGTTGATGAACCGGGGCGGGATCACCATGCGTCTGGTTGAA
TTCAGTCAGGCCATGATGGGGCATTTTCGCGGCGGGTTGGCGCATGTGAACATCCTGTCCTCCATGCTGTTTGCCGGGCT
TTCGGGGTCTGCCGTGGCCGATATATCCGCACTCGGGTCGATGTTGATCCCGGCGATGGAAAAACAGGGCTATAGCCGCA
AATTCGCCGCCGCGATCACGGCGGCCAGTTCCGTGATCGGGCCGATCATCCCGCCCTCGGGCATCATGATCATCTATGCC
TATGTGATGGGCGAAAGCGTTGCCGCCCTGTTTCTGGCGGGCATTGTACCCGGAGTGATGGTGGGCCTTGGGTTGATGTT
CATGGTCAAGATCATGGCTGACAAATATGATTTTCCCGTCGCCACCAAAAAACACACGTGGGGCGAACGCGGGCAGGCCA
GCCTCAAGGCGTTTTTTCCGCTGATGACCCCGGTGATCATTCTCGGCGGTATTCTGGCAGGCGTTTTTACCCCGACCGAG
GCGGCGGCGGTCGCCGTGGCCTATGCGCTTTTCATCGGCCTCTTCGTGATGCGCAGCCTCAAGCTGAGCGAGTTGCCGGA
TGTGCTGGGCCGCGCGGGGCTCACATCGGCGGTTGTGCTGTTGCTGGTCGGTGCGGCGATGGCGTTCAAAACCGTTGTCA
GCCTCAGCCACGCGCCCGAAGCCATGGCCGAATTCGTGCTGGCGCTCACGTCCAACCCGCTCATCCTGCTGTTTTTGATC
AACCTTTTGCTCTTTGCGGTGGGGATGTTCTTGGATGCGGGGCCTGCGATTATCATCCTTGGGCCAATTCTGGGGCCAAT
TTTCGTCAGCCTCGGCGTGGACCCGATCCATTTTGCCATCATCATGAGCGTCAACCTGACCGTCGGGCTGGCCACACCGC
CGATGGGGCTGGTGCTCTTTGTCGCCTCCTCGGTTTCGGGCGAGCGGGTCGAGGCGATTTCAAAGGCGATCCTGCCGTTT
CTGGCGGTCGAAATCGTGGTGATTTTCCTGATCACCTACATACCGGCCATTTCCATGACCATCCCGCGACTGACGGGCTT
TGCCAACTGA

Upstream 100 bases:

>100_bases
TGTCAACGTGGAACTGATCCTGCGCGCAATTGTCAAACTGCTGGGCGGTGCGGATCGCCTGCCTGTCATTCCGCATGATG
AGAAAGTCGGGGCGGAATAG

Downstream 100 bases:

>100_bases
CACATCATCCAACTGGGAGGAATAAATGATAAAACAAACCCTGAAATGCGCGCTCCTTGCGGCCTTGCTCGCCGGGACGG
CGATTGCGGCACAGGCGCAG

Product: TRAP-type transporter, DctM subunit, putative

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLVWFLPLFLLFLLIGLPVFFGLLAAPGLLLWLNGQEKDITLLYRNVYNGIDSFPLMAIPFFMLAGELMNRGGITMRLVE
FSQAMMGHFRGGLAHVNILSSMLFAGLSGSAVADISALGSMLIPAMEKQGYSRKFAAAITAASSVIGPIIPPSGIMIIYA
YVMGESVAALFLAGIVPGVMVGLGLMFMVKIMADKYDFPVATKKHTWGERGQASLKAFFPLMTPVIILGGILAGVFTPTE
AAAVAVAYALFIGLFVMRSLKLSELPDVLGRAGLTSAVVLLLVGAAMAFKTVVSLSHAPEAMAEFVLALTSNPLILLFLI
NLLLFAVGMFLDAGPAIIILGPILGPIFVSLGVDPIHFAIIMSVNLTVGLATPPMGLVLFVASSVSGERVEAISKAILPF
LAVEIVVIFLITYIPAISMTIPRLTGFAN

Sequences:

>Translated_429_residues
MLVWFLPLFLLFLLIGLPVFFGLLAAPGLLLWLNGQEKDITLLYRNVYNGIDSFPLMAIPFFMLAGELMNRGGITMRLVE
FSQAMMGHFRGGLAHVNILSSMLFAGLSGSAVADISALGSMLIPAMEKQGYSRKFAAAITAASSVIGPIIPPSGIMIIYA
YVMGESVAALFLAGIVPGVMVGLGLMFMVKIMADKYDFPVATKKHTWGERGQASLKAFFPLMTPVIILGGILAGVFTPTE
AAAVAVAYALFIGLFVMRSLKLSELPDVLGRAGLTSAVVLLLVGAAMAFKTVVSLSHAPEAMAEFVLALTSNPLILLFLI
NLLLFAVGMFLDAGPAIIILGPILGPIFVSLGVDPIHFAIIMSVNLTVGLATPPMGLVLFVASSVSGERVEAISKAILPF
LAVEIVVIFLITYIPAISMTIPRLTGFAN
>Mature_429_residues
MLVWFLPLFLLFLLIGLPVFFGLLAAPGLLLWLNGQEKDITLLYRNVYNGIDSFPLMAIPFFMLAGELMNRGGITMRLVE
FSQAMMGHFRGGLAHVNILSSMLFAGLSGSAVADISALGSMLIPAMEKQGYSRKFAAAITAASSVIGPIIPPSGIMIIYA
YVMGESVAALFLAGIVPGVMVGLGLMFMVKIMADKYDFPVATKKHTWGERGQASLKAFFPLMTPVIILGGILAGVFTPTE
AAAVAVAYALFIGLFVMRSLKLSELPDVLGRAGLTSAVVLLLVGAAMAFKTVVSLSHAPEAMAEFVLALTSNPLILLFLI
NLLLFAVGMFLDAGPAIIILGPILGPIFVSLGVDPIHFAIIMSVNLTVGLATPPMGLVLFVASSVSGERVEAISKAILPF
LAVEIVVIFLITYIPAISMTIPRLTGFAN

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=402, Percent_Identity=37.5621890547264, Blast_Score=228, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45440; Mature: 45440

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVWFLPLFLLFLLIGLPVFFGLLAAPGLLLWLNGQEKDITLLYRNVYNGIDSFPLMAIP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHH
FFMLAGELMNRGGITMRLVEFSQAMMGHFRGGLAHVNILSSMLFAGLSGSAVADISALGS
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MLIPAMEKQGYSRKFAAAITAASSVIGPIIPPSGIMIIYAYVMGESVAALFLAGIVPGVM
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLGLMFMVKIMADKYDFPVATKKHTWGERGQASLKAFFPLMTPVIILGGILAGVFTPTE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AAAVAVAYALFIGLFVMRSLKLSELPDVLGRAGLTSAVVLLLVGAAMAFKTVVSLSHAPE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
AMAEFVLALTSNPLILLFLINLLLFAVGMFLDAGPAIIILGPILGPIFVSLGVDPIHFAI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHHH
IMSVNLTVGLATPPMGLVLFVASSVSGERVEAISKAILPFLAVEIVVIFLITYIPAISMT
HEEEHEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPRLTGFAN
HHHHCCCCC
>Mature Secondary Structure
MLVWFLPLFLLFLLIGLPVFFGLLAAPGLLLWLNGQEKDITLLYRNVYNGIDSFPLMAIP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHH
FFMLAGELMNRGGITMRLVEFSQAMMGHFRGGLAHVNILSSMLFAGLSGSAVADISALGS
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MLIPAMEKQGYSRKFAAAITAASSVIGPIIPPSGIMIIYAYVMGESVAALFLAGIVPGVM
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLGLMFMVKIMADKYDFPVATKKHTWGERGQASLKAFFPLMTPVIILGGILAGVFTPTE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AAAVAVAYALFIGLFVMRSLKLSELPDVLGRAGLTSAVVLLLVGAAMAFKTVVSLSHAPE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
AMAEFVLALTSNPLILLFLINLLLFAVGMFLDAGPAIIILGPILGPIFVSLGVDPIHFAI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHHH
IMSVNLTVGLATPPMGLVLFVASSVSGERVEAISKAILPFLAVEIVVIFLITYIPAISMT
HEEEHEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPRLTGFAN
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]