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The map label for this gene is lhr [C]

Identifier: 110679386

GI number: 110679386

Start: 2010675

End: 2013128

Strand: Reverse

Name: lhr [C]

Synonym: RD1_2108

Alternate gene names: 110679386

Gene position: 2013128-2010675 (Counterclockwise)

Preceding gene: 110679387

Following gene: 110679385

Centisome position: 48.71

GC content: 62.1

Gene sequence:

>2454_bases
ATGACCGGCGTGCCGCAGAAATTCACCGATTGGTTCGCCTCGAAGGGCTGGCAAATCCATCCGCACCAGCTTGACATGCT
GGCGCGCGCGCATGATCCGGCGTTACTGCTCATTGCGCCGACGGGCGGCGGCAAGACATTGGCGGGTTTCCTGCCAACGC
TGATTGATCTGGCCACTGCGCCACGGGATGGATTGCACACGCTTTACATCTCTCCTCTCAAAGCCCTGGCGGCAGACATA
AAGCGCAACCTGACAACCCCTGTGACTGAGATGGACCTGCCCATCCGGGTTGAGGACCGAACAGGCGACACATCAGCCGC
GCGCAAGAAACGCCAGCGCGCTGACCCGCCGCATATTCTGCTGACAACACCCGAAAGCCTTGCGTTGCTGACCAGTTACG
AGGACGCACCGCGCATGTTTAAAGGGCTGCGGCGCGTTGTTGTGGATGAAATCCACGCGCTGGCAGAATCCAAACGCGGC
GATCAGTTGATGCTCGCACTTGCGCGGTTGCAGCGGCTTTGCCCGGACCTGCGCCGGGTCGGGTTGTCCGCGACTGTGGA
TGATCCGCAGGCCATCGCGCGCCTGCTGGCAAAACACCCCGACCCGTGCGAGATTTTGCAGGCCGACCCCGGCCCGGCCC
CAGATATCTCGATGCTGACCACGCCCAAGGCGCCGCCTTGGGCGGGGGGCAATGCGGCCTATGCCATTCCGGCAGTGCTT
GAGCAGATCAAGGCGCATCAAACAACGCTGATCTTTCACAATACCCGCGCGCAGGCCGAGATTTTCTTTCATAACCTGTG
GCTTGCCAATGAGGAGGGCTTGCCGATCGGCATCCATCACGGATCGCTGGACCGCCAACAGCGCGAAAAGGTCGAAGCGG
CGATGGTGCGCGGCGATCTGCGCGCGATTGTCTGCACCGGCAGCCTCGATCTGGGGATCGACTGGGGCGATGTGGACCTG
GTCATACAGATCGGCGCGCCCAAGAACGTCAAACGTCTGGTGCAGCGGATCGGACGCGCCAATCACCGTTACAACGCCCC
CTCCAAGGCGCTGCTCGTGCCTGCGAACCGGTTTGAAGTTGTCGAATGCCATGCCGCTCTGGATGCGGTTTACGCCGGGC
AGCTTGATGGTGAGCCGCGCGGGCGCGGGCCGCGTGATGTCTTGTGCCAACATATCCTCATCACCGCCTGCGCCGGACCA
TTTGACGCGGATGCGCTTTATGGTGAAGTGATCACCGTCGGGGCCTACGCTGACCTTACGCGCGCGGAATTCGATGAATG
TCTGACCTTCTGTGCGACGGGCGGATACGCGCTGCGCGCCTATGATCAATGGCAACGTCTGATGCAGAATGCCGATGGGT
TGTGGCACCTGCGCGACCCGCGCGCCGCACAGAAAATCCGCATGAACATCGGCACGATACAGGACACGGACACGCTGAAA
GTACGCTTGCAACGCAGCCGTGGCGGCAAACCTCTGGGCGAGATCGAGGAAGGCTTTGCCGCAACACTGACACCCGGCGA
TACCTTTCTGATCGGCGGGCAGATCGTGCGCTATGAGGGATTGCGCGAAATGACCGTCGAGGTCAGCCGCAACGCTGCCA
AGAAGCCCAAGGTTGCCACGTTCCTCGGAACGAAATTCGCAACCTCCACGCAGCTCAGTGCCCGCGTTGTCGAAATATTT
CAGGACACCGCCTGGCCCTATCTGCCCGCACATACCGCCGATTGGCTGGCGCTACAGCGCGAACGCAGCCAATTGCCCGC
GCCGGGCCGTTTGCTGATCGAAAGCTTTGCCCACGACGGACGCGCGCAGACCGTCGTCTATGGCTTTGCGGGGCGAAACG
GGCAACAGACCCTTGGCCTTTTGCTGACCAAACGCATGGAGGAGATGGGGCTCGACCCGCTGGGATTTGTCGCGACAGAT
TACGCGACGCTGATCTGGGGGCTGCAACCTGTGACGGACCCCGCACCGCTGTTTGATCTCGAAGCGCTTGAAACCGGGCT
GGAAACCTGGCTGGCAGGCAACGCCGTCATGAAACGGACCTTTCGCGCCAGCGCGACAATCGCCGGTCTGATCCAACGCA
ACACGCCATCGGCGCGCAAGACAGGCCGGCAGGCGACCTTCAGTTCGGATATTCTTTACGACACATTGCAAAAATATGAC
CCCGAACATCTGTTGCTGGACGTCACCCGCGAGGAGGCGCTGCGCGGTCTGGTCGATTTTGGCCGGATCAGGGAGATGGC
AGAGCGTGTCGCGGGCCGGATCGACCATGTGACCCTGCCCCGCGTCAGCCCGCTCGCCGCACCGATGCTGTTGGAAATGG
GCCGCGTTCCCGTCAAGGGCGCTGCCGAGGAGCGGCTGCTCGCCGAAGAGGCCGAGCGTCTGATGAATGCGGCAGGTCTG
GCACAGATCACACCGCCGCCGAGCGACAAGCCGAAATGGCGCGTGGGCTGGTAA

Upstream 100 bases:

>100_bases
CATGGGCGAATATGTTCGTCAAAAGCGAAAAAATCGTCAAATAGGGTCAGAAACGCAGCGTGGTATTGGCCGTTGCGCTG
CCTGGCACTACAGTCTGGCC

Downstream 100 bases:

>100_bases
CCCCTTGTCAAGACCGCCGGAGTGCGCGATGAACAAACCATGAACTCCTACGAATTCTCCTTTTGTGGCGTGACGCTCTG
GGCGATGCCTTCGGGCGCGC

Product: DEAD-box ATP dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 817; Mature: 816

Protein sequence:

>817_residues
MTGVPQKFTDWFASKGWQIHPHQLDMLARAHDPALLLIAPTGGGKTLAGFLPTLIDLATAPRDGLHTLYISPLKALAADI
KRNLTTPVTEMDLPIRVEDRTGDTSAARKKRQRADPPHILLTTPESLALLTSYEDAPRMFKGLRRVVVDEIHALAESKRG
DQLMLALARLQRLCPDLRRVGLSATVDDPQAIARLLAKHPDPCEILQADPGPAPDISMLTTPKAPPWAGGNAAYAIPAVL
EQIKAHQTTLIFHNTRAQAEIFFHNLWLANEEGLPIGIHHGSLDRQQREKVEAAMVRGDLRAIVCTGSLDLGIDWGDVDL
VIQIGAPKNVKRLVQRIGRANHRYNAPSKALLVPANRFEVVECHAALDAVYAGQLDGEPRGRGPRDVLCQHILITACAGP
FDADALYGEVITVGAYADLTRAEFDECLTFCATGGYALRAYDQWQRLMQNADGLWHLRDPRAAQKIRMNIGTIQDTDTLK
VRLQRSRGGKPLGEIEEGFAATLTPGDTFLIGGQIVRYEGLREMTVEVSRNAAKKPKVATFLGTKFATSTQLSARVVEIF
QDTAWPYLPAHTADWLALQRERSQLPAPGRLLIESFAHDGRAQTVVYGFAGRNGQQTLGLLLTKRMEEMGLDPLGFVATD
YATLIWGLQPVTDPAPLFDLEALETGLETWLAGNAVMKRTFRASATIAGLIQRNTPSARKTGRQATFSSDILYDTLQKYD
PEHLLLDVTREEALRGLVDFGRIREMAERVAGRIDHVTLPRVSPLAAPMLLEMGRVPVKGAAEERLLAEEAERLMNAAGL
AQITPPPSDKPKWRVGW

Sequences:

>Translated_817_residues
MTGVPQKFTDWFASKGWQIHPHQLDMLARAHDPALLLIAPTGGGKTLAGFLPTLIDLATAPRDGLHTLYISPLKALAADI
KRNLTTPVTEMDLPIRVEDRTGDTSAARKKRQRADPPHILLTTPESLALLTSYEDAPRMFKGLRRVVVDEIHALAESKRG
DQLMLALARLQRLCPDLRRVGLSATVDDPQAIARLLAKHPDPCEILQADPGPAPDISMLTTPKAPPWAGGNAAYAIPAVL
EQIKAHQTTLIFHNTRAQAEIFFHNLWLANEEGLPIGIHHGSLDRQQREKVEAAMVRGDLRAIVCTGSLDLGIDWGDVDL
VIQIGAPKNVKRLVQRIGRANHRYNAPSKALLVPANRFEVVECHAALDAVYAGQLDGEPRGRGPRDVLCQHILITACAGP
FDADALYGEVITVGAYADLTRAEFDECLTFCATGGYALRAYDQWQRLMQNADGLWHLRDPRAAQKIRMNIGTIQDTDTLK
VRLQRSRGGKPLGEIEEGFAATLTPGDTFLIGGQIVRYEGLREMTVEVSRNAAKKPKVATFLGTKFATSTQLSARVVEIF
QDTAWPYLPAHTADWLALQRERSQLPAPGRLLIESFAHDGRAQTVVYGFAGRNGQQTLGLLLTKRMEEMGLDPLGFVATD
YATLIWGLQPVTDPAPLFDLEALETGLETWLAGNAVMKRTFRASATIAGLIQRNTPSARKTGRQATFSSDILYDTLQKYD
PEHLLLDVTREEALRGLVDFGRIREMAERVAGRIDHVTLPRVSPLAAPMLLEMGRVPVKGAAEERLLAEEAERLMNAAGL
AQITPPPSDKPKWRVGW
>Mature_816_residues
TGVPQKFTDWFASKGWQIHPHQLDMLARAHDPALLLIAPTGGGKTLAGFLPTLIDLATAPRDGLHTLYISPLKALAADIK
RNLTTPVTEMDLPIRVEDRTGDTSAARKKRQRADPPHILLTTPESLALLTSYEDAPRMFKGLRRVVVDEIHALAESKRGD
QLMLALARLQRLCPDLRRVGLSATVDDPQAIARLLAKHPDPCEILQADPGPAPDISMLTTPKAPPWAGGNAAYAIPAVLE
QIKAHQTTLIFHNTRAQAEIFFHNLWLANEEGLPIGIHHGSLDRQQREKVEAAMVRGDLRAIVCTGSLDLGIDWGDVDLV
IQIGAPKNVKRLVQRIGRANHRYNAPSKALLVPANRFEVVECHAALDAVYAGQLDGEPRGRGPRDVLCQHILITACAGPF
DADALYGEVITVGAYADLTRAEFDECLTFCATGGYALRAYDQWQRLMQNADGLWHLRDPRAAQKIRMNIGTIQDTDTLKV
RLQRSRGGKPLGEIEEGFAATLTPGDTFLIGGQIVRYEGLREMTVEVSRNAAKKPKVATFLGTKFATSTQLSARVVEIFQ
DTAWPYLPAHTADWLALQRERSQLPAPGRLLIESFAHDGRAQTVVYGFAGRNGQQTLGLLLTKRMEEMGLDPLGFVATDY
ATLIWGLQPVTDPAPLFDLEALETGLETWLAGNAVMKRTFRASATIAGLIQRNTPSARKTGRQATFSSDILYDTLQKYDP
EHLLLDVTREEALRGLVDFGRIREMAERVAGRIDHVTLPRVSPLAAPMLLEMGRVPVKGAAEERLLAEEAERLMNAAGLA
QITPPPSDKPKWRVGW

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=861, Percent_Identity=27.2938443670151, Blast_Score=229, Evalue=8e-61,
Organism=Escherichia coli, GI48994977, Length=372, Percent_Identity=26.3440860215054, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI9755332, Length=348, Percent_Identity=25.5747126436782, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 89821; Mature: 89690

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVPQKFTDWFASKGWQIHPHQLDMLARAHDPALLLIAPTGGGKTLAGFLPTLIDLATA
CCCCCHHHHHHHHCCCCEECHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCC
PRDGLHTLYISPLKALAADIKRNLTTPVTEMDLPIRVEDRTGDTSAARKKRQRADPPHIL
CCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEE
LTTPESLALLTSYEDAPRMFKGLRRVVVDEIHALAESKRGDQLMLALARLQRLCPDLRRV
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHC
GLSATVDDPQAIARLLAKHPDPCEILQADPGPAPDISMLTTPKAPPWAGGNAAYAIPAVL
CCCCCCCCHHHHHHHHHCCCCCHHEEECCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHH
EQIKAHQTTLIFHNTRAQAEIFFHNLWLANEEGLPIGIHHGSLDRQQREKVEAAMVRGDL
HHHHHCCEEEEEECCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
RAIVCTGSLDLGIDWGDVDLVIQIGAPKNVKRLVQRIGRANHRYNAPSKALLVPANRFEV
EEEEEECCEEECCEECCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEE
VECHAALDAVYAGQLDGEPRGRGPRDVLCQHILITACAGPFDADALYGEVITVGAYADLT
EEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCEEECCHHHHH
RAEFDECLTFCATGGYALRAYDQWQRLMQNADGLWHLRDPRAAQKIRMNIGTIQDTDTLK
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCCCCEE
VRLQRSRGGKPLGEIEEGFAATLTPGDTFLIGGQIVRYEGLREMTVEVSRNAAKKPKVAT
EEEECCCCCCCHHHHHCCCEEEECCCCEEEECCEEEEECCHHHHHHHHHHCCCCCCCEEH
FLGTKFATSTQLSARVVEIFQDTAWPYLPAHTADWLALQRERSQLPAPGRLLIESFAHDG
HHCCHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
RAQTVVYGFAGRNGQQTLGLLLTKRMEEMGLDPLGFVATDYATLIWGLQPVTDPAPLFDL
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
EALETGLETWLAGNAVMKRTFRASATIAGLIQRNTPSARKTGRQATFSSDILYDTLQKYD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHCC
PEHLLLDVTREEALRGLVDFGRIREMAERVAGRIDHVTLPRVSPLAAPMLLEMGRVPVKG
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHCCCCCCC
AAEERLLAEEAERLMNAAGLAQITPPPSDKPKWRVGW
CHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEECCC
>Mature Secondary Structure 
TGVPQKFTDWFASKGWQIHPHQLDMLARAHDPALLLIAPTGGGKTLAGFLPTLIDLATA
CCCCHHHHHHHHCCCCEECHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCC
PRDGLHTLYISPLKALAADIKRNLTTPVTEMDLPIRVEDRTGDTSAARKKRQRADPPHIL
CCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEE
LTTPESLALLTSYEDAPRMFKGLRRVVVDEIHALAESKRGDQLMLALARLQRLCPDLRRV
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHC
GLSATVDDPQAIARLLAKHPDPCEILQADPGPAPDISMLTTPKAPPWAGGNAAYAIPAVL
CCCCCCCCHHHHHHHHHCCCCCHHEEECCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHH
EQIKAHQTTLIFHNTRAQAEIFFHNLWLANEEGLPIGIHHGSLDRQQREKVEAAMVRGDL
HHHHHCCEEEEEECCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
RAIVCTGSLDLGIDWGDVDLVIQIGAPKNVKRLVQRIGRANHRYNAPSKALLVPANRFEV
EEEEEECCEEECCEECCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEE
VECHAALDAVYAGQLDGEPRGRGPRDVLCQHILITACAGPFDADALYGEVITVGAYADLT
EEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCEEECCHHHHH
RAEFDECLTFCATGGYALRAYDQWQRLMQNADGLWHLRDPRAAQKIRMNIGTIQDTDTLK
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCCCCEE
VRLQRSRGGKPLGEIEEGFAATLTPGDTFLIGGQIVRYEGLREMTVEVSRNAAKKPKVAT
EEEECCCCCCCHHHHHCCCEEEECCCCEEEECCEEEEECCHHHHHHHHHHCCCCCCCEEH
FLGTKFATSTQLSARVVEIFQDTAWPYLPAHTADWLALQRERSQLPAPGRLLIESFAHDG
HHCCHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
RAQTVVYGFAGRNGQQTLGLLLTKRMEEMGLDPLGFVATDYATLIWGLQPVTDPAPLFDL
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
EALETGLETWLAGNAVMKRTFRASATIAGLIQRNTPSARKTGRQATFSSDILYDTLQKYD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHCC
PEHLLLDVTREEALRGLVDFGRIREMAERVAGRIDHVTLPRVSPLAAPMLLEMGRVPVKG
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHCCCCCCC
AAEERLLAEEAERLMNAAGLAQITPPPSDKPKWRVGW
CHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]