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The map label for this gene is engA

Identifier: 110679080

GI number: 110679080

Start: 1710618

End: 1712096

Strand: Direct

Name: engA

Synonym: RD1_1783

Alternate gene names: 110679080

Gene position: 1710618-1712096 (Clockwise)

Preceding gene: 110679079

Following gene: 110679082

Centisome position: 41.39

GC content: 61.93

Gene sequence:

>1479_bases
ATGTCTTTCACGCTCGCCATCGTAGGGCGGCCCAATGTGGGCAAATCCACGCTGTTCAACCGTCTGGTGGGCAAGCGTCT
TGCCCTTGTGGATGACCAGCCGGGCGTTACACGCGATTTGCGCGAGGGGGCGGCGCGGCTGGCGGATCTGCGGTTTACGG
TGATTGATACCGCAGGGCTTGAAGATGTGACCGATGACAGCCTGCAGGGGCGGATGCGCCGTTTGACAGAGCGCGCGGTT
GATATGGCGGACATCTGCCTCTTCATGGTGGATGCGCGGGTTGGCATCACGCCCACTGATCTGGTGTTCGCTGATATTCT
GCGCAAACGCGCGGGGCATGTCGTTCTGGCGGCCAACAAGGCCGAAGGGGCGGCTGCGGATGCCGGTGTGATCGAGGCCT
ATAGTCTCGGTCTGGGGGAGCCGATCCGCCTGTCTGCGGAACATGGGGAGGGGTTGAACGACCTTTATACCCATCTGATG
CCGCTGGCGGATGCCTATGCCGAACGCGCCGCCGAAGACGCACCCGAAACAGATGTCGCGCTGGATGAGGACAGCGGTGA
CATGGAGGCGGCGCTCCGCATGCCAACGGCCAACAAGCCGTTGCAGGTCGCGGTTGTCGGGCGGCCCAATGCGGGCAAAT
CCACGCTGGTCAACCAGATCCTTGGCGAAGACCGATTGCTCACCGGGCCCGAAGCAGGGATCACGCGCGATGCCATTTCG
CTGCGCACGGATTGGGTCGGGCCGGAGGGGGATGTTATCCCCATGCGGATCTTCGACACGGCAGGCATGCGCAAAAAGGC
CAAGGTGCAGGAAAAGCTGGAAAAACTGTCGGTCGGTGACGGATTGCGGGCGGTGAAATTCGCCGAAGTGGTCGTCGTGC
TGCTGGATGCTGCGATCCCCTTTGAACAGCAGGATTTGCGCATCGCCGATCTGGCCGAGCGTGAGGGGCGCGCGGTCGTC
GTTGCGGTCAACAAATGGGACATCGAGGAAAACAAACAGGCCAAGTTGAATGAGTTGCGTGAGAGCTTTGAGCGGCTTTT
GCCGCAGTTGCGCGGCGCCCCTTTGGTCACGGTCTCGGCGCGGACCGGGCGGGGTCTTGATCGGTTGCACAAGGCTGTTC
TGCGCGCCTATGAGGTCTGGAACCGCCGCGTCACCACCGCGCAACTGAACCGCTGGCTTGCCGGCATGCTGGAGGCGCAT
CCACCCCCCGCGCCGCAGGGCAAACGGATCAAGCTGCGCTATATGACGCAGGCGAAAACACGCCCGCCGGGATTTGTGGT
GATGTGTTCGCATCCCGATAAGGTGCCGGACAGTTACAACCGCTATCTGGTGAACGGATTGCGGCTCGACTTTGATATGC
CGGGAACGCCGATCCGGTTGTGGATGCGCGGTCAGAACGATGCCAACCCCTATAAGGGGCGCAAAAAGGCGCCGCCTTCG
AAACTGCGCAAACACACCGACGGGCGTCGCAAGGATTAA

Upstream 100 bases:

>100_bases
GTTCTTTATGTCGTGTCGTCAAATGGCCGATTGCATGCTTTCCGTTGACGCGGCTTTGCGGTAAAGCGCAGGACAATTCC
TGACATCCGGAGCCTTTGCC

Downstream 100 bases:

>100_bases
AGCGTCGTGCGATAAGCCTTGGTCACGTAACGCGGCCTGAAATGAATGATCTCAATGCGTTACGAGGTGACTGATGTTTC
AGCTATCTCGTCAGACGTTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSFTLAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDLREGAARLADLRFTVIDTAGLEDVTDDSLQGRMRRLTERAV
DMADICLFMVDARVGITPTDLVFADILRKRAGHVVLAANKAEGAAADAGVIEAYSLGLGEPIRLSAEHGEGLNDLYTHLM
PLADAYAERAAEDAPETDVALDEDSGDMEAALRMPTANKPLQVAVVGRPNAGKSTLVNQILGEDRLLTGPEAGITRDAIS
LRTDWVGPEGDVIPMRIFDTAGMRKKAKVQEKLEKLSVGDGLRAVKFAEVVVVLLDAAIPFEQQDLRIADLAEREGRAVV
VAVNKWDIEENKQAKLNELRESFERLLPQLRGAPLVTVSARTGRGLDRLHKAVLRAYEVWNRRVTTAQLNRWLAGMLEAH
PPPAPQGKRIKLRYMTQAKTRPPGFVVMCSHPDKVPDSYNRYLVNGLRLDFDMPGTPIRLWMRGQNDANPYKGRKKAPPS
KLRKHTDGRRKD

Sequences:

>Translated_492_residues
MSFTLAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDLREGAARLADLRFTVIDTAGLEDVTDDSLQGRMRRLTERAV
DMADICLFMVDARVGITPTDLVFADILRKRAGHVVLAANKAEGAAADAGVIEAYSLGLGEPIRLSAEHGEGLNDLYTHLM
PLADAYAERAAEDAPETDVALDEDSGDMEAALRMPTANKPLQVAVVGRPNAGKSTLVNQILGEDRLLTGPEAGITRDAIS
LRTDWVGPEGDVIPMRIFDTAGMRKKAKVQEKLEKLSVGDGLRAVKFAEVVVVLLDAAIPFEQQDLRIADLAEREGRAVV
VAVNKWDIEENKQAKLNELRESFERLLPQLRGAPLVTVSARTGRGLDRLHKAVLRAYEVWNRRVTTAQLNRWLAGMLEAH
PPPAPQGKRIKLRYMTQAKTRPPGFVVMCSHPDKVPDSYNRYLVNGLRLDFDMPGTPIRLWMRGQNDANPYKGRKKAPPS
KLRKHTDGRRKD
>Mature_491_residues
SFTLAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDLREGAARLADLRFTVIDTAGLEDVTDDSLQGRMRRLTERAVD
MADICLFMVDARVGITPTDLVFADILRKRAGHVVLAANKAEGAAADAGVIEAYSLGLGEPIRLSAEHGEGLNDLYTHLMP
LADAYAERAAEDAPETDVALDEDSGDMEAALRMPTANKPLQVAVVGRPNAGKSTLVNQILGEDRLLTGPEAGITRDAISL
RTDWVGPEGDVIPMRIFDTAGMRKKAKVQEKLEKLSVGDGLRAVKFAEVVVVLLDAAIPFEQQDLRIADLAEREGRAVVV
AVNKWDIEENKQAKLNELRESFERLLPQLRGAPLVTVSARTGRGLDRLHKAVLRAYEVWNRRVTTAQLNRWLAGMLEAHP
PPAPQGKRIKLRYMTQAKTRPPGFVVMCSHPDKVPDSYNRYLVNGLRLDFDMPGTPIRLWMRGQNDANPYKGRKKAPPSK
LRKHTDGRRKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=485, Percent_Identity=39.1752577319588, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI2367268, Length=158, Percent_Identity=34.8101265822785, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=123, Percent_Identity=31.7073170731707, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=186, Percent_Identity=28.494623655914, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_ROSDO (Q169E2)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682087.1
- ProteinModelPortal:   Q169E2
- SMR:   Q169E2
- STRING:   Q169E2
- GeneID:   4196956
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1783
- NMPDR:   fig|375451.6.peg.1668
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q169E2
- ProtClustDB:   PRK00093
- BioCyc:   RDEN375451:RD1_1783-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR001806
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00449
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 54257; Mature: 54126

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTLAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDLREGAARLADLRFTVIDTAGL
CCEEEEEEECCCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCC
EDVTDDSLQGRMRRLTERAVDMADICLFMVDARVGITPTDLVFADILRKRAGHVVLAANK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECC
AEGAAADAGVIEAYSLGLGEPIRLSAEHGEGLNDLYTHLMPLADAYAERAAEDAPETDVA
CCCCCCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LDEDSGDMEAALRMPTANKPLQVAVVGRPNAGKSTLVNQILGEDRLLTGPEAGITRDAIS
ECCCCCCCHHEEECCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCHHHHH
LRTDWVGPEGDVIPMRIFDTAGMRKKAKVQEKLEKLSVGDGLRAVKFAEVVVVLLDAAIP
HEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
FEQQDLRIADLAEREGRAVVVAVNKWDIEENKQAKLNELRESFERLLPQLRGAPLVTVSA
CCCCCCCHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
RTGRGLDRLHKAVLRAYEVWNRRVTTAQLNRWLAGMLEAHPPPAPQGKRIKLRYMTQAKT
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCC
RPPGFVVMCSHPDKVPDSYNRYLVNGLRLDFDMPGTPIRLWMRGQNDANPYKGRKKAPPS
CCCCEEEEECCCCCCCCHHHHHHHCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHH
KLRKHTDGRRKD
HHHHCCCCCCCC
>Mature Secondary Structure 
SFTLAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDLREGAARLADLRFTVIDTAGL
CEEEEEEECCCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCC
EDVTDDSLQGRMRRLTERAVDMADICLFMVDARVGITPTDLVFADILRKRAGHVVLAANK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECC
AEGAAADAGVIEAYSLGLGEPIRLSAEHGEGLNDLYTHLMPLADAYAERAAEDAPETDVA
CCCCCCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LDEDSGDMEAALRMPTANKPLQVAVVGRPNAGKSTLVNQILGEDRLLTGPEAGITRDAIS
ECCCCCCCHHEEECCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCHHHHH
LRTDWVGPEGDVIPMRIFDTAGMRKKAKVQEKLEKLSVGDGLRAVKFAEVVVVLLDAAIP
HEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
FEQQDLRIADLAEREGRAVVVAVNKWDIEENKQAKLNELRESFERLLPQLRGAPLVTVSA
CCCCCCCHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
RTGRGLDRLHKAVLRAYEVWNRRVTTAQLNRWLAGMLEAHPPPAPQGKRIKLRYMTQAKT
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCC
RPPGFVVMCSHPDKVPDSYNRYLVNGLRLDFDMPGTPIRLWMRGQNDANPYKGRKKAPPS
CCCCEEEEECCCCCCCCHHHHHHHCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHH
KLRKHTDGRRKD
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA