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The map label for this gene is efp

Identifier: 110679046

GI number: 110679046

Start: 1673634

End: 1674197

Strand: Direct

Name: efp

Synonym: RD1_1746

Alternate gene names: 110679046

Gene position: 1673634-1674197 (Clockwise)

Preceding gene: 110679044

Following gene: 110679048

Centisome position: 40.49

GC content: 56.21

Gene sequence:

>564_bases
ATGCCTAAAATCAACGGAAACGAAATCCGGCCCGGAAACGTGCTTGAACACAATGATGGTCTTTGGGCCGCGGTAAAGGT
CGATCATGTCAAGCCGGGGAAGGGCGGGGCTTTTGCCCAGGTCGAGATGCGCAACCTGCGCAACGGGTCCAAATTGAACG
AGCGGTTCCGGTCTGCGGACAAGGTGGAACGCGTGCGTCTCGAACAAAAAGACCAGCAGTTTCTTTATGAAGATGCGGGT
ATGTTGGTCGTGATGGACACCGAGACATATGAGCAGGTGCAACTGCCTGCGGAGCTTTTGGGCGAACGTCGCCCGTTTTT
GCAGGATGGCATGACCATCGTGGTGGAATTCTACGAAGAAGAGGCGCTGAACGCGACCTTGCCCCAGAAGGTGGTCTGCA
AAATCGTGGAAACCGAGGCCGTGGTCAAAGGCCAGACTGCCGCAAAATCCTTCAAGCCGGCCCTGTTGGAGAACGGCGTG
AAGGTCATGGTCCCCCCCTTCGTCGGGCAGGATGAGAATATCGTGGTCAACACCGAGACCATGGAATACTCCGAACGCGC
GTGA

Upstream 100 bases:

>100_bases
TAGGGCGTTGACCACGACATATCGTCGGGTTGTCACCCAACAGCCTCCCATATATAGGAGCGGGTAATAATTCATCAACC
TTTTGTATCGGTTTAGACAC

Downstream 100 bases:

>100_bases
GCGTCCTGGCATCGCGCGCCGGGCCTCACATCGCGGGGTCAGGCGATGCGGTGCACTTCCGCCGCGCCCGCCTGCATTGG
CCCCGTTGCACGGTCATAGC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPKINGNEIRPGNVLEHNDGLWAAVKVDHVKPGKGGAFAQVEMRNLRNGSKLNERFRSADKVERVRLEQKDQQFLYEDAG
MLVVMDTETYEQVQLPAELLGERRPFLQDGMTIVVEFYEEEALNATLPQKVVCKIVETEAVVKGQTAAKSFKPALLENGV
KVMVPPFVGQDENIVVNTETMEYSERA

Sequences:

>Translated_187_residues
MPKINGNEIRPGNVLEHNDGLWAAVKVDHVKPGKGGAFAQVEMRNLRNGSKLNERFRSADKVERVRLEQKDQQFLYEDAG
MLVVMDTETYEQVQLPAELLGERRPFLQDGMTIVVEFYEEEALNATLPQKVVCKIVETEAVVKGQTAAKSFKPALLENGV
KVMVPPFVGQDENIVVNTETMEYSERA
>Mature_186_residues
PKINGNEIRPGNVLEHNDGLWAAVKVDHVKPGKGGAFAQVEMRNLRNGSKLNERFRSADKVERVRLEQKDQQFLYEDAGM
LVVMDTETYEQVQLPAELLGERRPFLQDGMTIVVEFYEEEALNATLPQKVVCKIVETEAVVKGQTAAKSFKPALLENGVK
VMVPPFVGQDENIVVNTETMEYSERA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=186, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI87082061, Length=191, Percent_Identity=32.9842931937173, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_ROSDO (Q169H6)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682053.1
- ProteinModelPortal:   Q169H6
- SMR:   Q169H6
- STRING:   Q169H6
- GeneID:   4196961
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1746
- NMPDR:   fig|375451.6.peg.1633
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q169H6
- ProtClustDB:   PRK00529
- BioCyc:   RDEN375451:RD1_1746-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21020; Mature: 20889

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKINGNEIRPGNVLEHNDGLWAAVKVDHVKPGKGGAFAQVEMRNLRNGSKLNERFRSAD
CCCCCCCEECCCCCEECCCCEEEEEEEECCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHH
KVERVRLEQKDQQFLYEDAGMLVVMDTETYEQVQLPAELLGERRPFLQDGMTIVVEFYEE
HHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCHHHHCCCCCHHHCCEEEEEEEHHH
EALNATLPQKVVCKIVETEAVVKGQTAAKSFKPALLENGVKVMVPPFVGQDENIVVNTET
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCEEEECCCCCCCCCEEEECCC
MEYSERA
CCCCCCC
>Mature Secondary Structure 
PKINGNEIRPGNVLEHNDGLWAAVKVDHVKPGKGGAFAQVEMRNLRNGSKLNERFRSAD
CCCCCCEECCCCCEECCCCEEEEEEEECCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHH
KVERVRLEQKDQQFLYEDAGMLVVMDTETYEQVQLPAELLGERRPFLQDGMTIVVEFYEE
HHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCHHHHCCCCCHHHCCEEEEEEEHHH
EALNATLPQKVVCKIVETEAVVKGQTAAKSFKPALLENGVKVMVPPFVGQDENIVVNTET
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCEEEECCCCCCCCCEEEECCC
MEYSERA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA