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The map label for this gene is hutC [H]

Identifier: 110679020

GI number: 110679020

Start: 1650682

End: 1651383

Strand: Direct

Name: hutC [H]

Synonym: RD1_1719

Alternate gene names: 110679020

Gene position: 1650682-1651383 (Clockwise)

Preceding gene: 110679012

Following gene: 110679021

Centisome position: 39.94

GC content: 59.4

Gene sequence:

>702_bases
TTGACTGGTCAAACCCGCCTTTCCTGGACTGATGTGCGTGATGAGATACAGGCGCGTATTCTCGACCGGACATATGCACC
GGGGGACAAGCTGCCGCGCGACAACGATCTCGCTTTGGGGTTGGGATGCGCGCGCACGACCGTGCACCGCGCGATGCAGG
ACCTCGCGCGGATAGGATTGGTCGAACGTAAGCGAAAAGGCGGAACCCATGTCAGGGCCGACCCGGTGACGCGCGCCACC
TTTGATATCCCGATCACCCGGCGTGAGGTCGAGCAGCGCGGCAGTACCTATGACTACCGGCTGATCAGCAGCGCGGTGGA
GCCCATGCCGGAGTCAGTCCTACTGCGTTTTGGCAGCAGCGAGCCGGGCGAAGCCTTGCATGTCAAAGCCGTGCATCTGT
CTGACAGCAAACCATATATCTTTGAAGATCGCTGGATAGACATCACAACAACGCCCGATATCCTGCAGGTCGACCTTGCC
GGTAGCAGCGCCAACGAATGGCTTGTGCGCAACAAGCCCTACAGCAAGCTCGATGTCCGCTTCTTTGCCGTGAATGCCAA
AGGTGAAAACGCTGAACACCTGTCTGTCGCGGCAGGAGAGGCCTTGCTGGTGATTGAACGCACCACATGGATCGGTTCGG
CTCCGATCACGACGGTTCGATCCGTGACGGCCCCGGGGTATCAACTGTCGGCGCAAAACTGA

Upstream 100 bases:

>100_bases
CGCGCATGCCACTCATTTGCGCGAAACATCCGCAGAGTCTTGCAAGCAGCCTGTTTGACCGGGCAGCCCCGCTCCGGCGG
TGGCGGCGGGAGGCAGCCGT

Downstream 100 bases:

>100_bases
TCACGCTGCGATGCATCTTTTTGACTGGCCGAGCAGCGGATCGTCTCTTAACTTCTTGTCTGTCAGCGCCTGCCACTTGA
CGCCGACCTGCGCAAGAGCG

Product: histidine utilization repressor, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTGQTRLSWTDVRDEIQARILDRTYAPGDKLPRDNDLALGLGCARTTVHRAMQDLARIGLVERKRKGGTHVRADPVTRAT
FDIPITRREVEQRGSTYDYRLISSAVEPMPESVLLRFGSSEPGEALHVKAVHLSDSKPYIFEDRWIDITTTPDILQVDLA
GSSANEWLVRNKPYSKLDVRFFAVNAKGENAEHLSVAAGEALLVIERTTWIGSAPITTVRSVTAPGYQLSAQN

Sequences:

>Translated_233_residues
MTGQTRLSWTDVRDEIQARILDRTYAPGDKLPRDNDLALGLGCARTTVHRAMQDLARIGLVERKRKGGTHVRADPVTRAT
FDIPITRREVEQRGSTYDYRLISSAVEPMPESVLLRFGSSEPGEALHVKAVHLSDSKPYIFEDRWIDITTTPDILQVDLA
GSSANEWLVRNKPYSKLDVRFFAVNAKGENAEHLSVAAGEALLVIERTTWIGSAPITTVRSVTAPGYQLSAQN
>Mature_232_residues
TGQTRLSWTDVRDEIQARILDRTYAPGDKLPRDNDLALGLGCARTTVHRAMQDLARIGLVERKRKGGTHVRADPVTRATF
DIPITRREVEQRGSTYDYRLISSAVEPMPESVLLRFGSSEPGEALHVKAVHLSDSKPYIFEDRWIDITTTPDILQVDLAG
SSANEWLVRNKPYSKLDVRFFAVNAKGENAEHLSVAAGEALLVIERTTWIGSAPITTVRSVTAPGYQLSAQN

Specific function: Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010248
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 25884; Mature: 25752

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGQTRLSWTDVRDEIQARILDRTYAPGDKLPRDNDLALGLGCARTTVHRAMQDLARIGL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCH
VERKRKGGTHVRADPVTRATFDIPITRREVEQRGSTYDYRLISSAVEPMPESVLLRFGSS
HHHHHCCCCEEEECCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHEEECCC
EPGEALHVKAVHLSDSKPYIFEDRWIDITTTPDILQVDLAGSSANEWLVRNKPYSKLDVR
CCCCEEEEEEEEECCCCCEEEECCEEEEECCCCEEEEEECCCCCCCCEEECCCCCEEEEE
FFAVNAKGENAEHLSVAAGEALLVIERTTWIGSAPITTVRSVTAPGYQLSAQN
EEEEECCCCCCCEEEEECCCEEEEEEECEECCCCCCHHHEECCCCCEEEECCC
>Mature Secondary Structure 
TGQTRLSWTDVRDEIQARILDRTYAPGDKLPRDNDLALGLGCARTTVHRAMQDLARIGL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCH
VERKRKGGTHVRADPVTRATFDIPITRREVEQRGSTYDYRLISSAVEPMPESVLLRFGSS
HHHHHCCCCEEEECCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHEEECCC
EPGEALHVKAVHLSDSKPYIFEDRWIDITTTPDILQVDLAGSSANEWLVRNKPYSKLDVR
CCCCEEEEEEEEECCCCCEEEECCEEEEECCCCEEEEEECCCCCCCCEEECCCCCEEEEE
FFAVNAKGENAEHLSVAAGEALLVIERTTWIGSAPITTVRSVTAPGYQLSAQN
EEEEECCCCCCCEEEEECCCEEEEEEECEECCCCCCHHHEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2203753 [H]