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The map label for this gene is sdhB [H]

Identifier: 110678936

GI number: 110678936

Start: 1569669

End: 1570448

Strand: Direct

Name: sdhB [H]

Synonym: RD1_1630

Alternate gene names: 110678936

Gene position: 1569669-1570448 (Clockwise)

Preceding gene: 110678935

Following gene: 110678937

Centisome position: 37.98

GC content: 55.0

Gene sequence:

>780_bases
ATGGTTCAACTGACGCTTCCGAAGAACTCCCGTATGACCAAGGGAAAAACCTGGCCCAAACCCGAAGGGGCGACCAACCT
GCGTAAATTCAGCATTTACCGCTGGAACCCTGATGACGGTCAAAACCCACGCGTGGATACGTATTTTGTCGATATGGATA
CATGCGGGCCGATGATTTTGGACGCGCTGATCAAGATCAAGAACGAAATCGACCCGACGCTGACGTTCCGGCGCTCTTGC
CGCGAAGGTATTTGCGGATCCTGTGCGATGAACATCGACGGGATCAACACTCTGGCCTGTATCTACGGCATGGATGAGGT
AAAGGGAGATGTCAGGATCTACCCGCTGCCCCACATGCCTGTGGTCAAGGACCTTATTCCGGACCTGACGCATTTTTACG
CCCAACACGCATCGACCATGCCATGGCTTGAAACCAAGACGAACCGCCCGGCGAAAGAGTGGAAGCAATCCATTGACGAC
CGCAAAAAGCTGGACGGTCTTTATGAATGCGTGATGTGCGCCTGCTGCTCAACGTCATGCCCGTCTTACTGGTGGAATGG
GGACCGTTACCTTGGACCGGCCGCTTTGCTGCATGCCTATCGCTGGATCATTGACAGCCGGGATGAGGCCACGGGCGAAC
GGCTCGACGATCTGGAAGATCCGTTCAAACTGTATCGCTGCCACACCATCATGAACTGCGCCAAGACCTGCCCGAAGGGC
CTCAACCCTGCCGAAGCGATTGCGAACATCAAAAAGATGATGGTGGAGCGGCGCGTCTAA

Upstream 100 bases:

>100_bases
CGCGCAGTGCTGAGCCGCAGCGCCACACAGGATTGTTTGCGCGCTGCGGCCCCGGCGGCTGGCTTGACGCTTTAGGACAT
AAGAACAGGAGACCTTAAAA

Downstream 100 bases:

>100_bases
GCTTTCGCCATGGAAAGCGCGGTCGACAGCATCTGGGGTGCGCTCGTTCTTGCAACACTTGCGGGCGCTTCCATCCCTCT
GGGCGCGTGGCTGGGCACTT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVQLTLPKNSRMTKGKTWPKPEGATNLRKFSIYRWNPDDGQNPRVDTYFVDMDTCGPMILDALIKIKNEIDPTLTFRRSC
REGICGSCAMNIDGINTLACIYGMDEVKGDVRIYPLPHMPVVKDLIPDLTHFYAQHASTMPWLETKTNRPAKEWKQSIDD
RKKLDGLYECVMCACCSTSCPSYWWNGDRYLGPAALLHAYRWIIDSRDEATGERLDDLEDPFKLYRCHTIMNCAKTCPKG
LNPAEAIANIKKMMVERRV

Sequences:

>Translated_259_residues
MVQLTLPKNSRMTKGKTWPKPEGATNLRKFSIYRWNPDDGQNPRVDTYFVDMDTCGPMILDALIKIKNEIDPTLTFRRSC
REGICGSCAMNIDGINTLACIYGMDEVKGDVRIYPLPHMPVVKDLIPDLTHFYAQHASTMPWLETKTNRPAKEWKQSIDD
RKKLDGLYECVMCACCSTSCPSYWWNGDRYLGPAALLHAYRWIIDSRDEATGERLDDLEDPFKLYRCHTIMNCAKTCPKG
LNPAEAIANIKKMMVERRV
>Mature_259_residues
MVQLTLPKNSRMTKGKTWPKPEGATNLRKFSIYRWNPDDGQNPRVDTYFVDMDTCGPMILDALIKIKNEIDPTLTFRRSC
REGICGSCAMNIDGINTLACIYGMDEVKGDVRIYPLPHMPVVKDLIPDLTHFYAQHASTMPWLETKTNRPAKEWKQSIDD
RKKLDGLYECVMCACCSTSCPSYWWNGDRYLGPAALLHAYRWIIDSRDEATGERLDDLEDPFKLYRCHTIMNCAKTCPKG
LNPAEAIANIKKMMVERRV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=236, Percent_Identity=66.5254237288136, Blast_Score=339, Evalue=1e-93,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=52.991452991453, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI1790596, Length=225, Percent_Identity=31.5555555555556, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17533915, Length=233, Percent_Identity=62.6609442060086, Blast_Score=317, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6322987, Length=232, Percent_Identity=62.9310344827586, Blast_Score=312, Evalue=4e-86,
Organism=Drosophila melanogaster, GI17137106, Length=245, Percent_Identity=63.265306122449, Blast_Score=342, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24643156, Length=233, Percent_Identity=63.9484978540773, Blast_Score=324, Evalue=5e-89,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29681; Mature: 29681

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
9.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQLTLPKNSRMTKGKTWPKPEGATNLRKFSIYRWNPDDGQNPRVDTYFVDMDTCGPMIL
CEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCHHHH
DALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGINTLACIYGMDEVKGDVRIYPLPHMP
HHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCHHHHCCCEEEEECCCCH
VVKDLIPDLTHFYAQHASTMPWLETKTNRPAKEWKQSIDDRKKLDGLYECVMCACCSTSC
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGDRYLGPAALLHAYRWIIDSRDEATGERLDDLEDPFKLYRCHTIMNCAKTCPKG
CCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LNPAEAIANIKKMMVERRV
CCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVQLTLPKNSRMTKGKTWPKPEGATNLRKFSIYRWNPDDGQNPRVDTYFVDMDTCGPMIL
CEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCHHHH
DALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGINTLACIYGMDEVKGDVRIYPLPHMP
HHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCHHHHCCCEEEEECCCCH
VVKDLIPDLTHFYAQHASTMPWLETKTNRPAKEWKQSIDDRKKLDGLYECVMCACCSTSC
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGDRYLGPAALLHAYRWIIDSRDEATGERLDDLEDPFKLYRCHTIMNCAKTCPKG
CCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LNPAEAIANIKKMMVERRV
CCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA