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The map label for this gene is crp [C]

Identifier: 110678861

GI number: 110678861

Start: 1477772

End: 1478464

Strand: Reverse

Name: crp [C]

Synonym: RD1_1553

Alternate gene names: 110678861

Gene position: 1478464-1477772 (Counterclockwise)

Preceding gene: 110678864

Following gene: 110678852

Centisome position: 35.77

GC content: 56.71

Gene sequence:

>693_bases
ATGAATATCGCACTTCTGACCGACCAGGACCGTGAGGTGCTCAAGTCTTCCCTGCTGTGTTCCGCGATGAGCGATGCCGA
TCTTGCCAGCATCATCACGCGAGGAGGGGTCATCGAATACAGGCGGTCCGAATACCTGTTCGAACAGGGCGAACGTGCCG
AGACGATTTATCTTATTCTGGAGGGCTGGGCACAGATTACCCGCGATGAGGTGGACGGTTCAAACACCCTCGTGGAAGCC
TTTCACAAGGGCGATTGTCTGGCCGAGGCACCCGCACTGCTGGGCAAAGCCTATCCGGCGTCCTGTCAGGCCATGACTGA
CATGCGCGCCCTTGCCCTTGATGGTCCGAAGCTGCTGGATTTGATGCAAACCAACCGGACGGTTCTGACGCAGTCGTTGG
CGGCACTGTTCCAGAAATTGCATGGGCTTGTGGATGATGTCGAATGGTTGAAATCCCGCACGATCCGGGAACGATTGGTG
AGATTCCTGCTGCAGCAGTCGGAACATATCAATGATGGACAGGAATTCATGCTACCCTTCAGCAAGTCTCTGATCGCTGC
CAAGATCGGAACGAGTCCGCAACAGCTCTCACGCACCTTCACGGAACTGAAAGAGCACGGTGTGACGACACGCGGCCAGA
AAGCCACGATCCGGGAGCGGCGCGTTTTGCGGGCGATGATCCGAAGGCACTAG

Upstream 100 bases:

>100_bases
GCAGGTGTAAAAAATAATTTACAGTTCTGTGGTGCGCAGCGTTTACGATACGGGGCAATAGTGTAGTGTGAAATCAGTTT
GAAAATCGTAGGACCGCCCC

Downstream 100 bases:

>100_bases
AGCGTATCACGTAACTCGTTGGAATCATTAATTTCAGACGGTATTTCGTACTTCATTTTTCTCGCATGACGCTCTAGGCG
CGCAGGGCGAGTTCTGCTTC

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Regulator Of Biofilm Formation Fnr Family; Transcription Regulator Protein Crp/Fnr Family; Transcriptional Activator FtrB; Transcriptional Regulator Dnr; Cyclic AMP Receptor Protein; Transcriptional Regulator DnrS; Transcriptional Regulator Dnr Type; Transcriptional Activator; DnrE Protein; Fnr-Like Transcriptional Activator; DNR Protein; Transcription Regulator Protein; Fnr-Like Regulatory Protein; FNR-Like Transcriptional Regulator; Transcription Regulator; CAMP-Bindin Transcriptional Regulator; Transcriptional Regulator CAP/Crp Family; Transcriptional Regulator Dnr/Nnr Type

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNIALLTDQDREVLKSSLLCSAMSDADLASIITRGGVIEYRRSEYLFEQGERAETIYLILEGWAQITRDEVDGSNTLVEA
FHKGDCLAEAPALLGKAYPASCQAMTDMRALALDGPKLLDLMQTNRTVLTQSLAALFQKLHGLVDDVEWLKSRTIRERLV
RFLLQQSEHINDGQEFMLPFSKSLIAAKIGTSPQQLSRTFTELKEHGVTTRGQKATIRERRVLRAMIRRH

Sequences:

>Translated_230_residues
MNIALLTDQDREVLKSSLLCSAMSDADLASIITRGGVIEYRRSEYLFEQGERAETIYLILEGWAQITRDEVDGSNTLVEA
FHKGDCLAEAPALLGKAYPASCQAMTDMRALALDGPKLLDLMQTNRTVLTQSLAALFQKLHGLVDDVEWLKSRTIRERLV
RFLLQQSEHINDGQEFMLPFSKSLIAAKIGTSPQQLSRTFTELKEHGVTTRGQKATIRERRVLRAMIRRH
>Mature_230_residues
MNIALLTDQDREVLKSSLLCSAMSDADLASIITRGGVIEYRRSEYLFEQGERAETIYLILEGWAQITRDEVDGSNTLVEA
FHKGDCLAEAPALLGKAYPASCQAMTDMRALALDGPKLLDLMQTNRTVLTQSLAALFQKLHGLVDDVEWLKSRTIRERLV
RFLLQQSEHINDGQEFMLPFSKSLIAAKIGTSPQQLSRTFTELKEHGVTTRGQKATIRERRVLRAMIRRH

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25933; Mature: 25933

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIALLTDQDREVLKSSLLCSAMSDADLASIITRGGVIEYRRSEYLFEQGERAETIYLIL
CCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEHHHH
EGWAQITRDEVDGSNTLVEAFHKGDCLAEAPALLGKAYPASCQAMTDMRALALDGPKLLD
HHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
LMQTNRTVLTQSLAALFQKLHGLVDDVEWLKSRTIRERLVRFLLQQSEHINDGQEFMLPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SKSLIAAKIGTSPQQLSRTFTELKEHGVTTRGQKATIRERRVLRAMIRRH
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIALLTDQDREVLKSSLLCSAMSDADLASIITRGGVIEYRRSEYLFEQGERAETIYLIL
CCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEHHHH
EGWAQITRDEVDGSNTLVEAFHKGDCLAEAPALLGKAYPASCQAMTDMRALALDGPKLLD
HHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
LMQTNRTVLTQSLAALFQKLHGLVDDVEWLKSRTIRERLVRFLLQQSEHINDGQEFMLPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SKSLIAAKIGTSPQQLSRTFTELKEHGVTTRGQKATIRERRVLRAMIRRH
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA