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The map label for this gene is siaP [H]

Identifier: 110678849

GI number: 110678849

Start: 1462487

End: 1463470

Strand: Direct

Name: siaP [H]

Synonym: RD1_1539

Alternate gene names: 110678849

Gene position: 1462487-1463470 (Clockwise)

Preceding gene: 110678848

Following gene: 110678850

Centisome position: 35.38

GC content: 58.94

Gene sequence:

>984_bases
ATGTCGAAATTAACTACGTTCGCGGCTGTTGCATTTGCGGTGCTGGCGCTGCCATTCTCCGCATCAGCACAGGACCGGGA
GTTCCGTCTTGGGCTTATCACACCCCCTGTTCATGTGTGGAATCAGGAGGTTGCAGCGCTCAGCGATACGCTTTCCGAGA
TGTCGGATGGCCGTTTTACCGTCGTTGCCTTCCCGTCAGGCCAGTTGGGCAGCGAAACGACGATGCTGCAACAATTGCAG
ACCGGCGCACTTGATATGGCCTGGCTGACGTCAGCGGAGATTACGAACCGCGTGCCCGCCATGGGCGCCCTGCATGCGCC
GTTTCTGGTCGATAACATCGGTGATGCGGCCAAGGTCCTGCGCTCGGATGTAGCACGCGAAATCCTTGACGAATTGCCGC
GCGCCACGGGTACGGTCGGCGTCTGCTATGCCATGACGGGCATGCGCCAGCTTTTGACGCAGAACCCGGTTGAAAGCGCT
GCTGAACTGGACGGCTTGCGGTTCCGCATTACACCTGCCCCGCCGATCCGCACCTTCTTCGAGATGTTCGGCGCGGCCCC
CGCACCAATGCCGCTGACACAGGTTTATGACGCTCTGGCCAATGGGCAGATCGACGCGATCGACATGGACCACGAGTCGA
TCATCAACTTTGGTTACTACGACCATGCGTCCTATATGATGGAGACAAACCACCACCTCTTCGGGATGGTGGCGTTGGTG
TCCGGGCGCGTCTGGGCGGGACTTTCGCCCGAAGATCAAACGATCCTGCGCGACGCAATCCAGATCCACTGTGACCGCAC
CATCGACCGTTTCGTCGAAGGCGAAGACGCCAAGCTGGAGCAATTGCGTCAGGTCGAGGGACTGAACATCGTTGAGAACG
TGGGGCCTGAATTCTTTGGTGATATCGTCGAACGTTGGGACGCGGAATGGGCTGAGCAGACGCCCTACGTCCAGCGCATG
CGTGATCTCGTCGCTGATTTCTGA

Upstream 100 bases:

>100_bases
TGTTCAGGGTAGCCCCGGCCTATGTCGAGGGTATCCCAAGGACGCGGATTTGAATAGTTTCAGGCCATGCAGAATGCGTG
GCTGTCAGGGAGATCACAAA

Downstream 100 bases:

>100_bases
TCCAACTCACTTCGGCACGGGGCGGCCACTGTGGCTGCCCGGTGCCAATTGAACAGACGAGAGACGCGCCTTCATGCTCA
GTCGATCCCTCAGCAGACTG

Product: C4-dicarboxylate binding protein, putative

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSKLTTFAAVAFAVLALPFSASAQDREFRLGLITPPVHVWNQEVAALSDTLSEMSDGRFTVVAFPSGQLGSETTMLQQLQ
TGALDMAWLTSAEITNRVPAMGALHAPFLVDNIGDAAKVLRSDVAREILDELPRATGTVGVCYAMTGMRQLLTQNPVESA
AELDGLRFRITPAPPIRTFFEMFGAAPAPMPLTQVYDALANGQIDAIDMDHESIINFGYYDHASYMMETNHHLFGMVALV
SGRVWAGLSPEDQTILRDAIQIHCDRTIDRFVEGEDAKLEQLRQVEGLNIVENVGPEFFGDIVERWDAEWAEQTPYVQRM
RDLVADF

Sequences:

>Translated_327_residues
MSKLTTFAAVAFAVLALPFSASAQDREFRLGLITPPVHVWNQEVAALSDTLSEMSDGRFTVVAFPSGQLGSETTMLQQLQ
TGALDMAWLTSAEITNRVPAMGALHAPFLVDNIGDAAKVLRSDVAREILDELPRATGTVGVCYAMTGMRQLLTQNPVESA
AELDGLRFRITPAPPIRTFFEMFGAAPAPMPLTQVYDALANGQIDAIDMDHESIINFGYYDHASYMMETNHHLFGMVALV
SGRVWAGLSPEDQTILRDAIQIHCDRTIDRFVEGEDAKLEQLRQVEGLNIVENVGPEFFGDIVERWDAEWAEQTPYVQRM
RDLVADF
>Mature_326_residues
SKLTTFAAVAFAVLALPFSASAQDREFRLGLITPPVHVWNQEVAALSDTLSEMSDGRFTVVAFPSGQLGSETTMLQQLQT
GALDMAWLTSAEITNRVPAMGALHAPFLVDNIGDAAKVLRSDVAREILDELPRATGTVGVCYAMTGMRQLLTQNPVESAA
ELDGLRFRITPAPPIRTFFEMFGAAPAPMPLTQVYDALANGQIDAIDMDHESIINFGYYDHASYMMETNHHLFGMVALVS
GRVWAGLSPEDQTILRDAIQIHCDRTIDRFVEGEDAKLEQLRQVEGLNIVENVGPEFFGDIVERWDAEWAEQTPYVQRMR
DLVADF

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=294, Percent_Identity=24.4897959183673, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36126; Mature: 35995

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLTTFAAVAFAVLALPFSASAQDREFRLGLITPPVHVWNQEVAALSDTLSEMSDGRFT
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEE
VVAFPSGQLGSETTMLQQLQTGALDMAWLTSAEITNRVPAMGALHAPFLVDNIGDAAKVL
EEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCHHHHHH
RSDVAREILDELPRATGTVGVCYAMTGMRQLLTQNPVESAAELDGLRFRITPAPPIRTFF
HHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCHHHHHH
EMFGAAPAPMPLTQVYDALANGQIDAIDMDHESIINFGYYDHASYMMETNHHLFGMVALV
HHHCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHH
SGRVWAGLSPEDQTILRDAIQIHCDRTIDRFVEGEDAKLEQLRQVEGLNIVENVGPEFFG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHCCHHHHH
DIVERWDAEWAEQTPYVQRMRDLVADF
HHHHHHCHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLTTFAAVAFAVLALPFSASAQDREFRLGLITPPVHVWNQEVAALSDTLSEMSDGRFT
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEE
VVAFPSGQLGSETTMLQQLQTGALDMAWLTSAEITNRVPAMGALHAPFLVDNIGDAAKVL
EEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCHHHHHH
RSDVAREILDELPRATGTVGVCYAMTGMRQLLTQNPVESAAELDGLRFRITPAPPIRTFF
HHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCHHHHHH
EMFGAAPAPMPLTQVYDALANGQIDAIDMDHESIINFGYYDHASYMMETNHHLFGMVALV
HHHCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHH
SGRVWAGLSPEDQTILRDAIQIHCDRTIDRFVEGEDAKLEQLRQVEGLNIVENVGPEFFG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHCCHHHHH
DIVERWDAEWAEQTPYVQRMRDLVADF
HHHHHHCHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA