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The map label for this gene is arcA [H]

Identifier: 110678734

GI number: 110678734

Start: 1353486

End: 1354412

Strand: Reverse

Name: arcA [H]

Synonym: RD1_1416

Alternate gene names: 110678734

Gene position: 1354412-1353486 (Counterclockwise)

Preceding gene: 110678735

Following gene: 110678733

Centisome position: 32.77

GC content: 63.75

Gene sequence:

>927_bases
ATGACCAAGCAAAAATGCATTTTAATCGGCGTGCCGATGGATTGCGGCAAACGCCGTCAGGGTTGCCTGATGGGTCCGGA
TGCCTATCGCACCGCGGGGCTTGCCCCGGCCATCCGTGACCTCGGATATGTGGCCGAAGACCGCGGGAATATCAGCCCCG
GCGCTTTCACGCCTGACACGCATGACGGCAGGCTCTATGCCTTGAACGAAACAATCGCATGGACCAGGAGCCTCAAGGAG
GCGGCGCAGGTCGCCATGGCCGACGGTTTTCCGATCTTCATGGGGGGCGATCATGCGCTCTCGCTGGGCACGGTTGCCGG
GGTTGCGGCCCACGCCGCCGGGCAGAACCGTCCGCAATTCGTTTTGTGGCTCGATGCCCATCCCGACTATCACACGCCCG
ACACCACCGATTCCGGCAATCTGCACGGCACACCGCTGGGGTATCTGACCGGGCGCGGGGCCTTTGACGGCTTTCCCGAG
GTTGAGGTCAAAGTGCCCACCGGAAACGTCGCCATGATCGGCCTGCGCTCCGTCGATGCACCCGAACGGGAGGCGATACA
GGCGACCGACATTCAGGTCGCCGACATGCGCGCGATTGATGAAAACGGCATCGCCGCCCCCCTGCGCAGGTTTCTGGAAC
GGGTGGAGGCGGCGGGCGGCATGCTGCATGTCTCGCTCGATGTGGATTTCCTCGACCCTGCCATCGCACCCGCCGTTGGC
ACCACCGTGCCGGGGGGTGCGACCCTGCGCGAGGCCCATCTGGCGATGGAGATGCTGCACGACAGCGGCCTTGTGACCTC
GCTTGATCTGGTCGAACTCAACCCCTTCCTTGACGAACGCGGTCGCACTGCGTCGCTTATGGTCGAACTCACCGCGTCGC
TTTTGGGACGCCGCGTATTTGACCGCCCAACCCGCAGCTATTCCTGA

Upstream 100 bases:

>100_bases
AGAGGTACGCATGCGGTGAGGTCCACGGGCCAATCCGCATCCGCGAAAGCAAGATCATCGTGACGGCCGTCCAGAAACCA
ACTGCGCAAGAGGGCAAGAT

Downstream 100 bases:

>100_bases
GAGACATCATGGCCAACCCCTCCCCTTCCAAGCTCGCCTTCGTGCCCTTCGTCAGCGTCGAAAACATGATGAAACTGGTC
CACCACATCGGGATTGAAAC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTKQKCILIGVPMDCGKRRQGCLMGPDAYRTAGLAPAIRDLGYVAEDRGNISPGAFTPDTHDGRLYALNETIAWTRSLKE
AAQVAMADGFPIFMGGDHALSLGTVAGVAAHAAGQNRPQFVLWLDAHPDYHTPDTTDSGNLHGTPLGYLTGRGAFDGFPE
VEVKVPTGNVAMIGLRSVDAPEREAIQATDIQVADMRAIDENGIAAPLRRFLERVEAAGGMLHVSLDVDFLDPAIAPAVG
TTVPGGATLREAHLAMEMLHDSGLVTSLDLVELNPFLDERGRTASLMVELTASLLGRRVFDRPTRSYS

Sequences:

>Translated_308_residues
MTKQKCILIGVPMDCGKRRQGCLMGPDAYRTAGLAPAIRDLGYVAEDRGNISPGAFTPDTHDGRLYALNETIAWTRSLKE
AAQVAMADGFPIFMGGDHALSLGTVAGVAAHAAGQNRPQFVLWLDAHPDYHTPDTTDSGNLHGTPLGYLTGRGAFDGFPE
VEVKVPTGNVAMIGLRSVDAPEREAIQATDIQVADMRAIDENGIAAPLRRFLERVEAAGGMLHVSLDVDFLDPAIAPAVG
TTVPGGATLREAHLAMEMLHDSGLVTSLDLVELNPFLDERGRTASLMVELTASLLGRRVFDRPTRSYS
>Mature_307_residues
TKQKCILIGVPMDCGKRRQGCLMGPDAYRTAGLAPAIRDLGYVAEDRGNISPGAFTPDTHDGRLYALNETIAWTRSLKEA
AQVAMADGFPIFMGGDHALSLGTVAGVAAHAAGQNRPQFVLWLDAHPDYHTPDTTDSGNLHGTPLGYLTGRGAFDGFPEV
EVKVPTGNVAMIGLRSVDAPEREAIQATDIQVADMRAIDENGIAAPLRRFLERVEAAGGMLHVSLDVDFLDPAIAPAVGT
TVPGGATLREAHLAMEMLHDSGLVTSLDLVELNPFLDERGRTASLMVELTASLLGRRVFDRPTRSYS

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=309, Percent_Identity=38.8349514563107, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI10947139, Length=302, Percent_Identity=32.4503311258278, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71996843, Length=218, Percent_Identity=30.2752293577982, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325146, Length=291, Percent_Identity=33.6769759450172, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24638886, Length=314, Percent_Identity=32.1656050955414, Blast_Score=135, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32901; Mature: 32770

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQKCILIGVPMDCGKRRQGCLMGPDAYRTAGLAPAIRDLGYVAEDRGNISPGAFTPDT
CCCCCEEEEECCCCCCCCCCCCEECCHHHHHCCCCHHHHHHCCHHHCCCCCCCCCCCCCC
HDGRLYALNETIAWTRSLKEAAQVAMADGFPIFMGGDHALSLGTVAGVAAHAAGQNRPQF
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHHCCCCCCCE
VLWLDAHPDYHTPDTTDSGNLHGTPLGYLTGRGAFDGFPEVEVKVPTGNVAMIGLRSVDA
EEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCEEEEEEECCCC
PEREAIQATDIQVADMRAIDENGIAAPLRRFLERVEAAGGMLHVSLDVDFLDPAIAPAVG
CHHHCEEECCEEEEHHEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECHHCCCHHHHHCC
TTVPGGATLREAHLAMEMLHDSGLVTSLDLVELNPFLDERGRTASLMVELTASLLGRRVF
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHH
DRPTRSYS
CCCCCCCC
>Mature Secondary Structure 
TKQKCILIGVPMDCGKRRQGCLMGPDAYRTAGLAPAIRDLGYVAEDRGNISPGAFTPDT
CCCCEEEEECCCCCCCCCCCCEECCHHHHHCCCCHHHHHHCCHHHCCCCCCCCCCCCCC
HDGRLYALNETIAWTRSLKEAAQVAMADGFPIFMGGDHALSLGTVAGVAAHAAGQNRPQF
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHHCCCCCCCE
VLWLDAHPDYHTPDTTDSGNLHGTPLGYLTGRGAFDGFPEVEVKVPTGNVAMIGLRSVDA
EEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCEEEEEEECCCC
PEREAIQATDIQVADMRAIDENGIAAPLRRFLERVEAAGGMLHVSLDVDFLDPAIAPAVG
CHHHCEEECCEEEEHHEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECHHCCCHHHHHCC
TTVPGGATLREAHLAMEMLHDSGLVTSLDLVELNPFLDERGRTASLMVELTASLLGRRVF
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHH
DRPTRSYS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9375792 [H]