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The map label for this gene is etfA [H]

Identifier: 110678706

GI number: 110678706

Start: 1330718

End: 1331647

Strand: Reverse

Name: etfA [H]

Synonym: RD1_1387

Alternate gene names: 110678706

Gene position: 1331647-1330718 (Counterclockwise)

Preceding gene: 110678707

Following gene: 110678704

Centisome position: 32.22

GC content: 61.51

Gene sequence:

>930_bases
ATGGCCGTTCTTCTTCTTGCAGAAGTGACCGATGGCGCGCTGGCAATGGACGCGACCGCAAAGGCCGTCACCGCAGCGCA
AGCGCTGGGTGATGTGACACTGCTCTGCACCGGGGCAAGCTGCGCGGATGCAGCGGCTGAGGCTGCGACCATTCAGGGCG
TGGCCAAAGTGCTCTGTGCCGAGGATGCGATTTACGGCAAGCGATTGGCAGAGCCGGTTGCTGACCTGATCGTCTCGCTC
GCAGGTGACTACGAACACATCGCAGCGCCCGCGACGACGGATGCCAAGAATATCATGCCTCGTGTGGCGGCCTTGCTGGA
TGTCATGGTGATTTCGGACGCAACTGCCGTCATCGACGCCAACACGTTCGAGCGTCCGATCTACGCAGGCAACGCGATGC
AAACGGTCAAGACCGCCGACGCCAAGAAGGTCCTGACCTTCCGTGGCTCCACATTCGATGCGGCCCCGACAGGCGGTTCC
GCCAGTGTCCAGAACATCGGTGCTGCGGCAAATCCGGGCTTGAGCGAATGGGTCGAGGACAAGGTTGCTGCAAGCGACCG
CCCCGAGCTGACCTCGGCCGGTGTGGTCGTATCAGGCGGTCGCGGTGTGGGTTCCGAAGACGATTTCGCCCTGATCGAAA
AGCTGGCAGACAAGCTTGGCGCGGCGGTCGGCGCCTCCCGCGCCGCCGTGGATTCCGGCTATGCACCCAATGACTGGCAA
GTGGGACAGACCGGAAAAGTCGTAGCCCCCGAGCTTTATGTCGCCGTGGGCATTTCCGGTGCCATCCAGCATCTGGCCGG
TATGAAAGACAGCAAAATCATCGTGGCGATCAACAAGGACGAAGAAGCGCCCATCTTCCAGGTGGCGGATTACGGGCTCG
TCGCGGATCTGTTCACCGCAGTGCCGGAATTGATCGAAAAGCTCGACTGA

Upstream 100 bases:

>100_bases
AAATCATCAAGACTGAGGAACCGGCCGAACGGGCTGCCGGGATCAAGGTCGGTTCGGTGGACGAACTGGTATCCAAACTC
AAAGAATCGGGAGCAGTATA

Downstream 100 bases:

>100_bases
TCCTGCACGCATGACGTGATGAAAGGCCGTGGCATCCGTGCCGCGGCCTTTTTCTATACCAGATTTTCCAAAACGCTGCT
CAGTCTCATCGCGGCCTCGC

Product: electron transfer flavoprotein, alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAVLLLAEVTDGALAMDATAKAVTAAQALGDVTLLCTGASCADAAAEAATIQGVAKVLCAEDAIYGKRLAEPVADLIVSL
AGDYEHIAAPATTDAKNIMPRVAALLDVMVISDATAVIDANTFERPIYAGNAMQTVKTADAKKVLTFRGSTFDAAPTGGS
ASVQNIGAAANPGLSEWVEDKVAASDRPELTSAGVVVSGGRGVGSEDDFALIEKLADKLGAAVGASRAAVDSGYAPNDWQ
VGQTGKVVAPELYVAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFTAVPELIEKLD

Sequences:

>Translated_309_residues
MAVLLLAEVTDGALAMDATAKAVTAAQALGDVTLLCTGASCADAAAEAATIQGVAKVLCAEDAIYGKRLAEPVADLIVSL
AGDYEHIAAPATTDAKNIMPRVAALLDVMVISDATAVIDANTFERPIYAGNAMQTVKTADAKKVLTFRGSTFDAAPTGGS
ASVQNIGAAANPGLSEWVEDKVAASDRPELTSAGVVVSGGRGVGSEDDFALIEKLADKLGAAVGASRAAVDSGYAPNDWQ
VGQTGKVVAPELYVAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFTAVPELIEKLD
>Mature_308_residues
AVLLLAEVTDGALAMDATAKAVTAAQALGDVTLLCTGASCADAAAEAATIQGVAKVLCAEDAIYGKRLAEPVADLIVSLA
GDYEHIAAPATTDAKNIMPRVAALLDVMVISDATAVIDANTFERPIYAGNAMQTVKTADAKKVLTFRGSTFDAAPTGGSA
SVQNIGAAANPGLSEWVEDKVAASDRPELTSAGVVVSGGRGVGSEDDFALIEKLADKLGAAVGASRAAVDSGYAPNDWQV
GQTGKVVAPELYVAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFTAVPELIEKLD

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=55.3054662379421, Blast_Score=312, Evalue=3e-85,
Organism=Homo sapiens, GI189181759, Length=267, Percent_Identity=58.8014981273408, Blast_Score=296, Evalue=1e-80,
Organism=Escherichia coli, GI1786226, Length=233, Percent_Identity=36.0515021459227, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787990, Length=227, Percent_Identity=33.920704845815, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082157, Length=107, Percent_Identity=42.0560747663551, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=307, Percent_Identity=54.7231270358306, Blast_Score=302, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6325261, Length=307, Percent_Identity=43.6482084690554, Blast_Score=238, Evalue=1e-63,
Organism=Drosophila melanogaster, GI17136898, Length=295, Percent_Identity=55.9322033898305, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24652801, Length=295, Percent_Identity=55.9322033898305, Blast_Score=298, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31416; Mature: 31285

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLLLAEVTDGALAMDATAKAVTAAQALGDVTLLCTGASCADAAAEAATIQGVAKVLCA
CEEEEEEECCCCCEEHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
EDAIYGKRLAEPVADLIVSLAGDYEHIAAPATTDAKNIMPRVAALLDVMVISDATAVIDA
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEC
NTFERPIYAGNAMQTVKTADAKKVLTFRGSTFDAAPTGGSASVQNIGAAANPGLSEWVED
CCCCCCEECCCHHHHHHHCCHHEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHH
KVAASDRPELTSAGVVVSGGRGVGSEDDFALIEKLADKLGAAVGASRAAVDSGYAPNDWQ
HHCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
VGQTGKVVAPELYVAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFTA
CCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHH
VPELIEKLD
HHHHHHHCC
>Mature Secondary Structure 
AVLLLAEVTDGALAMDATAKAVTAAQALGDVTLLCTGASCADAAAEAATIQGVAKVLCA
EEEEEEECCCCCEEHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
EDAIYGKRLAEPVADLIVSLAGDYEHIAAPATTDAKNIMPRVAALLDVMVISDATAVIDA
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEC
NTFERPIYAGNAMQTVKTADAKKVLTFRGSTFDAAPTGGSASVQNIGAAANPGLSEWVED
CCCCCCEECCCHHHHHHHCCHHEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHH
KVAASDRPELTSAGVVVSGGRGVGSEDDFALIEKLADKLGAAVGASRAAVDSGYAPNDWQ
HHCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
VGQTGKVVAPELYVAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFTA
CCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHH
VPELIEKLD
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8376381; 1576992; 10026281 [H]