Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 110678687

GI number: 110678687

Start: 1314195

End: 1315103

Strand: Direct

Name: era [H]

Synonym: RD1_1367

Alternate gene names: 110678687

Gene position: 1314195-1315103 (Clockwise)

Preceding gene: 110678686

Following gene: 110678688

Centisome position: 31.8

GC content: 61.17

Gene sequence:

>909_bases
ATGAGTACACGTGCAGGATTTGTCGCACTGATCGGGGAGCCGAACGCGGGAAAGTCGACCTTGCTCAACCGCATGGTCGG
GGCAAAGGTGTCGATTGTCACGCATAAGGTGCAGACCACGCGCGCGCGCATTCGCGGCGTGGCCATGGAGGGCGACAGCC
AGATTGTTTTCGTGGACACACCCGGTCTTTTCCAGCCGCGCAGACGGCTTGACCGGGCCATGGTGGCCGCCGCATGGAGC
GGGGCAGCGGATGCGGATGTGGTTGTGTTGCTGGTTGAGGCGCATCGCGGTGTGACCGAGGGTGTTGAGCGTGTCCTTGA
GGGGCTGGCCGAGGTCGGGCAGGGCCGGATGGTCGCGCTGGCCATCAACAAGATTGACCGGGTACAGGCCGAAGCCTTGC
TGGCGCTCAGCAAAGACCTGAATGAGCGCTATGATTTTGTCGAAACCTTCATGATTTCGGCGGAGCGGGGGCACGGTGTG
GACACGCTGCGCGCATGGCTTGCGGGCAAGGTGCCGGAGGGGCCGTGGCTGTATCCGGAAGACCAGATTGCAGACCTGCC
CATGCGTACCATCGCTGCCGAGATGACGCGCGAGAAGCTGACGCTGCGCCTGCATCAGGAACTGCCCTATCAGATGACAG
TTGAGACGGAAGGCTGGGAAGAGCGCAAAGACGGCTCTGCCCGGATCGACCAGCTGATTTATGTGGTGCGCGATGGTCAC
AAGGGCATCGTTCTGGGCCACAAAGGCGAAACCATCAAAGCCGTGTCCAAAGCCGCGCGCGAGGAACTGGAAGAATTCCT
TGGCCGGCGCGTGCACTTGTTCCTGCAGGTCAAGGTCCGCCCGAATTGGCTGGATGAAGCGGAAAGATACACGCAGATGG
GTCTGGAGTTCAAAGACGGCAATGTCTGA

Upstream 100 bases:

>100_bases
GGATCAGCACCGGGGAAACGGATCAGGCCACGGCCGGGTCAAAGCGGCAGGCCGAACAAGCCGCGGCACAGGCCTTGCTG
GCCAAACTGGAGACAAGCGG

Downstream 100 bases:

>100_bases
ACGCGCCGCCCATATCCGCCGGTGTGTGGCGCAGGGCATGTGGCCATGCCCCAGCTGACGGCGCGGTTCTGGGTCGATGC
CTATCTGACACGGCTCAGGG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSTRAGFVALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGDSQIVFVDTPGLFQPRRRLDRAMVAAAWS
GAADADVVVLLVEAHRGVTEGVERVLEGLAEVGQGRMVALAINKIDRVQAEALLALSKDLNERYDFVETFMISAERGHGV
DTLRAWLAGKVPEGPWLYPEDQIADLPMRTIAAEMTREKLTLRLHQELPYQMTVETEGWEERKDGSARIDQLIYVVRDGH
KGIVLGHKGETIKAVSKAAREELEEFLGRRVHLFLQVKVRPNWLDEAERYTQMGLEFKDGNV

Sequences:

>Translated_302_residues
MSTRAGFVALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGDSQIVFVDTPGLFQPRRRLDRAMVAAAWS
GAADADVVVLLVEAHRGVTEGVERVLEGLAEVGQGRMVALAINKIDRVQAEALLALSKDLNERYDFVETFMISAERGHGV
DTLRAWLAGKVPEGPWLYPEDQIADLPMRTIAAEMTREKLTLRLHQELPYQMTVETEGWEERKDGSARIDQLIYVVRDGH
KGIVLGHKGETIKAVSKAAREELEEFLGRRVHLFLQVKVRPNWLDEAERYTQMGLEFKDGNV
>Mature_301_residues
STRAGFVALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGDSQIVFVDTPGLFQPRRRLDRAMVAAAWSG
AADADVVVLLVEAHRGVTEGVERVLEGLAEVGQGRMVALAINKIDRVQAEALLALSKDLNERYDFVETFMISAERGHGVD
TLRAWLAGKVPEGPWLYPEDQIADLPMRTIAAEMTREKLTLRLHQELPYQMTVETEGWEERKDGSARIDQLIYVVRDGHK
GIVLGHKGETIKAVSKAAREELEEFLGRRVHLFLQVKVRPNWLDEAERYTQMGLEFKDGNV

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=327, Percent_Identity=30.2752293577982, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=41.4965986394558, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI87082120, Length=166, Percent_Identity=31.3253012048193, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646434, Length=317, Percent_Identity=26.813880126183, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33678; Mature: 33547

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRAGFVALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGDSQIVFVDT
CCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEHHHHHHHHHHEEEEEECCCEEEEEEC
PGLFQPRRRLDRAMVAAAWSGAADADVVVLLVEAHRGVTEGVERVLEGLAEVGQGRMVAL
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEE
AINKIDRVQAEALLALSKDLNERYDFVETFMISAERGHGVDTLRAWLAGKVPEGPWLYPE
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
DQIADLPMRTIAAEMTREKLTLRLHQELPYQMTVETEGWEERKDGSARIDQLIYVVRDGH
CHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHEEEEEECCC
KGIVLGHKGETIKAVSKAAREELEEFLGRRVHLFLQVKVRPNWLDEAERYTQMGLEFKDG
CEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCHHHHHHHHHHCCCEECCC
NV
CC
>Mature Secondary Structure 
STRAGFVALIGEPNAGKSTLLNRMVGAKVSIVTHKVQTTRARIRGVAMEGDSQIVFVDT
CCCCCEEEEEECCCCCHHHHHHHHHCCEEEEEEHHHHHHHHHHEEEEEECCCEEEEEEC
PGLFQPRRRLDRAMVAAAWSGAADADVVVLLVEAHRGVTEGVERVLEGLAEVGQGRMVAL
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEE
AINKIDRVQAEALLALSKDLNERYDFVETFMISAERGHGVDTLRAWLAGKVPEGPWLYPE
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
DQIADLPMRTIAAEMTREKLTLRLHQELPYQMTVETEGWEERKDGSARIDQLIYVVRDGH
CHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHEEEEEECCC
KGIVLGHKGETIKAVSKAAREELEEFLGRRVHLFLQVKVRPNWLDEAERYTQMGLEFKDG
CEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCHHHHHHHHHHCCCEECCC
NV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA