Click here to switch to the map view.

The map label for this gene is mreB [H]

Identifier: 110678537

GI number: 110678537

Start: 1172789

End: 1173877

Strand: Reverse

Name: mreB [H]

Synonym: RD1_1209

Alternate gene names: 110678537

Gene position: 1173877-1172789 (Counterclockwise)

Preceding gene: 110678538

Following gene: 110678536

Centisome position: 28.4

GC content: 57.85

Gene sequence:

>1089_bases
ATGGGCTCGGATAAATCAGATTCGGGCAAGGTTATAAGCTTCATGGCTCTATTCGATAGTTTTCGTGGTCTTTTTTCGTC
AGATATGGCGATTGACCTCGGCACGGCAAACACGTTGGTTTACGTCAAAGGCCGTGGCATAATCTTGTCAGAGCCCTCGG
TGGTCGCCTATCACGTCAAGGATGGCGTGAAAAAAGTCCTTGCTGTTGGCGAAGATGCCAAATTGATGCTGGGACGTACC
CCCGGCAGCATCGAGGCAATTCGCCCCATGCGCGAAGGTGTGATCGCCGATTTCGATACGGCCGAGGAAATGATCAAACA
TTTCATCCGCAAGGTGCACAAGCGGTCCACCTTCTCGAAACCCAAGATTATCGTCTGCGTGCCCCATGGTGCAACGCCCG
TTGAAAAACGCGCTATCCGCCAGTCCGTTCTGAGTGCGGGTGCGCGCCGCGCAGGGCTGATTGCGGAACCCATCGCCGCG
GCCATTGGCGCCGGCATGCCGATCACGGACCCCACTGGCAACATGGTCGTGGACATCGGTGGCGGTACGACCGAGGTCGC
AGTCCTGTCTTTGGGTGATATCGTCTACGCCCGTTCGGTGCGCGTTGGCGGGGACCGGATGGACGAAGCGATCATCAGTT
ATCTGCGCCGTCAACAAAATCTGCTGGTCGGTGAAACCACGGCCGAACGGATCAAGACATCCATCGGCACGGCGCGAATG
CCTGATGACGGGCGTGGGACGTCAATGCAGATCAGGGGCCGTGACCTGTTGAATGGCGTCCCGAAAGAAATCGAAGTAAC
ACAGGCGCAGATTGCCGAGGCGCTGGCCGAACCCGTCCAGCAAATCTGCGAAGCGGTCATGACAGCGCTTGAGACAACGC
CCCCCGACCTCGCTGCGGATATCGTGGATCGTGGCGTGATGCTGACGGGCGGTGGCGCATTGCTGGGGGATCTTGACCTC
GCCCTGCGCGAACAAACCGGCCTTGCCGTATCAATTGCGGACGAGTCACTGAATTGCGTGGCTTTGGGCACCGGTAAGGC
CCTAGAATACGAAAAACAGCTGCGTCACGCCATCGACTACGACAGTTGA

Upstream 100 bases:

>100_bases
ATTCATCATTTTTTTCAAAAAGCAAGATGATGCCTAGAACATCGTTAACGCCCCTTTCACCATATCGCAGCTAAGCATAT
AACACAGGTCAACTGAGCCG

Downstream 100 bases:

>100_bases
TCGCAACGCATTAACCGCACCCCGTCAGAGGCAGGCATGCCCTGCTCCACTAGGGGGCAGGAGACCGAGGCCGGATGGCA
AAGGACAGGTCAAACGCAAA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MGSDKSDSGKVISFMALFDSFRGLFSSDMAIDLGTANTLVYVKGRGIILSEPSVVAYHVKDGVKKVLAVGEDAKLMLGRT
PGSIEAIRPMREGVIADFDTAEEMIKHFIRKVHKRSTFSKPKIIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEPIAA
AIGAGMPITDPTGNMVVDIGGGTTEVAVLSLGDIVYARSVRVGGDRMDEAIISYLRRQQNLLVGETTAERIKTSIGTARM
PDDGRGTSMQIRGRDLLNGVPKEIEVTQAQIAEALAEPVQQICEAVMTALETTPPDLAADIVDRGVMLTGGGALLGDLDL
ALREQTGLAVSIADESLNCVALGTGKALEYEKQLRHAIDYDS

Sequences:

>Translated_362_residues
MGSDKSDSGKVISFMALFDSFRGLFSSDMAIDLGTANTLVYVKGRGIILSEPSVVAYHVKDGVKKVLAVGEDAKLMLGRT
PGSIEAIRPMREGVIADFDTAEEMIKHFIRKVHKRSTFSKPKIIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEPIAA
AIGAGMPITDPTGNMVVDIGGGTTEVAVLSLGDIVYARSVRVGGDRMDEAIISYLRRQQNLLVGETTAERIKTSIGTARM
PDDGRGTSMQIRGRDLLNGVPKEIEVTQAQIAEALAEPVQQICEAVMTALETTPPDLAADIVDRGVMLTGGGALLGDLDL
ALREQTGLAVSIADESLNCVALGTGKALEYEKQLRHAIDYDS
>Mature_361_residues
GSDKSDSGKVISFMALFDSFRGLFSSDMAIDLGTANTLVYVKGRGIILSEPSVVAYHVKDGVKKVLAVGEDAKLMLGRTP
GSIEAIRPMREGVIADFDTAEEMIKHFIRKVHKRSTFSKPKIIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEPIAAA
IGAGMPITDPTGNMVVDIGGGTTEVAVLSLGDIVYARSVRVGGDRMDEAIISYLRRQQNLLVGETTAERIKTSIGTARMP
DDGRGTSMQIRGRDLLNGVPKEIEVTQAQIAEALAEPVQQICEAVMTALETTPPDLAADIVDRGVMLTGGGALLGDLDLA
LREQTGLAVSIADESLNCVALGTGKALEYEKQLRHAIDYDS

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=336, Percent_Identity=58.6309523809524, Blast_Score=383, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 38471; Mature: 38340

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSDKSDSGKVISFMALFDSFRGLFSSDMAIDLGTANTLVYVKGRGIILSEPSVVAYHVK
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCEEEEECCCEEEEHHH
DGVKKVLAVGEDAKLMLGRTPGSIEAIRPMREGVIADFDTAEEMIKHFIRKVHKRSTFSK
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
PKIIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEPIAAAIGAGMPITDPTGNMVVDIG
CEEEEEECCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEEC
GGTTEVAVLSLGDIVYARSVRVGGDRMDEAIISYLRRQQNLLVGETTAERIKTSIGTARM
CCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCC
PDDGRGTSMQIRGRDLLNGVPKEIEVTQAQIAEALAEPVQQICEAVMTALETTPPDLAAD
CCCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IVDRGVMLTGGGALLGDLDLALREQTGLAVSIADESLNCVALGTGKALEYEKQLRHAIDY
HHHCCEEEECCCCEEEHHHHHHHHCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHCCC
DS
CC
>Mature Secondary Structure 
GSDKSDSGKVISFMALFDSFRGLFSSDMAIDLGTANTLVYVKGRGIILSEPSVVAYHVK
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCEEEEECCCEEEEHHH
DGVKKVLAVGEDAKLMLGRTPGSIEAIRPMREGVIADFDTAEEMIKHFIRKVHKRSTFSK
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
PKIIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEPIAAAIGAGMPITDPTGNMVVDIG
CEEEEEECCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEEC
GGTTEVAVLSLGDIVYARSVRVGGDRMDEAIISYLRRQQNLLVGETTAERIKTSIGTARM
CCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCC
PDDGRGTSMQIRGRDLLNGVPKEIEVTQAQIAEALAEPVQQICEAVMTALETTPPDLAAD
CCCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IVDRGVMLTGGGALLGDLDLALREQTGLAVSIADESLNCVALGTGKALEYEKQLRHAIDY
HHHCCEEEECCCCEEEHHHHHHHHCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHCCC
DS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]