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The map label for this gene is aprE [H]

Identifier: 110678458

GI number: 110678458

Start: 1085941

End: 1087248

Strand: Reverse

Name: aprE [H]

Synonym: RD1_1123

Alternate gene names: 110678458

Gene position: 1087248-1085941 (Counterclockwise)

Preceding gene: 110678459

Following gene: 110678455

Centisome position: 26.31

GC content: 63.15

Gene sequence:

>1308_bases
ATGAGCGGCACGGAATGGGATTTCGAGGCGTCGCGCCGCCCCCGGTCGACTGGTCGCGGGCTGTTAACGCTGGTTTTTCT
GTTGGTCCTTCTTGGCTTGCTGGTGGGGGCCGTGTCCTGGGCGTCTTGGGCACGCATCGAGGTGATGGCCCGTGCGCAGG
GTGTTGTCGTACCCTCCGGACGTGCGCGGAATGTGGAAAGCCTTGAGGGCGGCATCGTGCGCGACATTCTGATTTCCGAA
GGCGATGCCGTGACACAGGGTCAGGTGTTGATCCGCATTGATGACATCGGGGCCGCGTCGACCCTTGGCGAAATCACCGC
GCGGCGCGATGCGATGCTGGCCAAGGCCCTGCGGCTCGAAGCAGAGTTGCTGGGCGAGGACGCTCCGGATTTTTCCAGCC
TCGGGCTGGCCGAAGATCACCCGCTCGCCCTGCGGGAGATGGCGCTTTTCGACAGCCGTCAGGCGGCTGATCTGTCCCAG
CGCACGGTGCTTGTCTCGCAGGTGGAGCAACGCTCTCAGGAGATCGAAGAGCTTGGCAGCGCCTTGGCCCGCATTGACGA
AAGCCTCGAATTGCTCGACGAGGAAATCGCCTTGCGCACAGCTTCCGGCGTCGTGCCACGCGCGCAAATCATCCCGATTG
AACGCGAGCGGACCAGAAAACGGCAGGAACGCGACTCCGTCCTCAGCCGCAGCCGTCAGGCCGTCACGGCACTGGGCGAA
GCCGAAGCGCGCGTGCGCGAACTGAACCTCAACCGGCGCGCAGAGATCAACACCGAACGCTCGGATACCCTGAATGAACT
CAGCGTCTTGGACGAAACCCTGAAACGCGCCTCCGATATCCTGAACCGCACCAGCCTGCGCGCGCCGGTCGAGGGCATCG
TGTCGGTCCTGAACGTCAATACGCTCGGATCCGTCATCGCACCGGGTGAAGAGGTCGCGCGCATTGTGCCCGCCGATGAC
AATCTAGAGGTCGAGGCGCGCGTGCGGCCCGAAGACATCGCGTTCATCCGCCTTGATCTGCCCGCAAAGGTGAAACTCAC
GTCCTTTGATTTCACGATCTACGGCGCACTGGAAGGCCGCGTCGTGCGCATTGGCGCAGATGCGGAGCGCGATGAAACAA
CCGGCGAGACGTATTTCCCCATCATCGTGCGCACGGACTCGAATGCGCTGTCGCGCAACGGTGAAACCCACGAAATCCGC
ACCGGCATGATCGCCTCGGTCGATATTCTGACCGGGGAACGGACGGTACTGGATTACCTGCTCAAACCGCTGCGCAAAGC
GCGCCTTGAGGCCCTGCGCGAGCGCTAG

Upstream 100 bases:

>100_bases
TTACACATGTGGCTGTCATGACCAGCGGCACCTTGCGCAGCTATGGACCCCGTGACGAGGTGCTGTCGTCGTTGAAAGAC
GCTGGCAAGGGCACGCCATC

Downstream 100 bases:

>100_bases
ACGATGGCCGTTTGCGCAGCACCCACGCTGTCTTCGAAAATCACTTCGACCTGCGCCGGGATACCACCACCTGCCGATCC
GACCTCGAACGCATTGCTGC

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSGTEWDFEASRRPRSTGRGLLTLVFLLVLLGLLVGAVSWASWARIEVMARAQGVVVPSGRARNVESLEGGIVRDILISE
GDAVTQGQVLIRIDDIGAASTLGEITARRDAMLAKALRLEAELLGEDAPDFSSLGLAEDHPLALREMALFDSRQAADLSQ
RTVLVSQVEQRSQEIEELGSALARIDESLELLDEEIALRTASGVVPRAQIIPIERERTRKRQERDSVLSRSRQAVTALGE
AEARVRELNLNRRAEINTERSDTLNELSVLDETLKRASDILNRTSLRAPVEGIVSVLNVNTLGSVIAPGEEVARIVPADD
NLEVEARVRPEDIAFIRLDLPAKVKLTSFDFTIYGALEGRVVRIGADAERDETTGETYFPIIVRTDSNALSRNGETHEIR
TGMIASVDILTGERTVLDYLLKPLRKARLEALRER

Sequences:

>Translated_435_residues
MSGTEWDFEASRRPRSTGRGLLTLVFLLVLLGLLVGAVSWASWARIEVMARAQGVVVPSGRARNVESLEGGIVRDILISE
GDAVTQGQVLIRIDDIGAASTLGEITARRDAMLAKALRLEAELLGEDAPDFSSLGLAEDHPLALREMALFDSRQAADLSQ
RTVLVSQVEQRSQEIEELGSALARIDESLELLDEEIALRTASGVVPRAQIIPIERERTRKRQERDSVLSRSRQAVTALGE
AEARVRELNLNRRAEINTERSDTLNELSVLDETLKRASDILNRTSLRAPVEGIVSVLNVNTLGSVIAPGEEVARIVPADD
NLEVEARVRPEDIAFIRLDLPAKVKLTSFDFTIYGALEGRVVRIGADAERDETTGETYFPIIVRTDSNALSRNGETHEIR
TGMIASVDILTGERTVLDYLLKPLRKARLEALRER
>Mature_434_residues
SGTEWDFEASRRPRSTGRGLLTLVFLLVLLGLLVGAVSWASWARIEVMARAQGVVVPSGRARNVESLEGGIVRDILISEG
DAVTQGQVLIRIDDIGAASTLGEITARRDAMLAKALRLEAELLGEDAPDFSSLGLAEDHPLALREMALFDSRQAADLSQR
TVLVSQVEQRSQEIEELGSALARIDESLELLDEEIALRTASGVVPRAQIIPIERERTRKRQERDSVLSRSRQAVTALGEA
EARVRELNLNRRAEINTERSDTLNELSVLDETLKRASDILNRTSLRAPVEGIVSVLNVNTLGSVIAPGEEVARIVPADDN
LEVEARVRPEDIAFIRLDLPAKVKLTSFDFTIYGALEGRVVRIGADAERDETTGETYFPIIVRTDSNALSRNGETHEIRT
GMIASVDILTGERTVLDYLLKPLRKARLEALRER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47894; Mature: 47763

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTEWDFEASRRPRSTGRGLLTLVFLLVLLGLLVGAVSWASWARIEVMARAQGVVVPSG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCC
RARNVESLEGGIVRDILISEGDAVTQGQVLIRIDDIGAASTLGEITARRDAMLAKALRLE
CCCCHHHHCCCCEEHHHCCCCCCEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
AELLGEDAPDFSSLGLAEDHPLALREMALFDSRQAADLSQRTVLVSQVEQRSQEIEELGS
HHHHCCCCCCHHHCCCCCCCCHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
ALARIDESLELLDEEIALRTASGVVPRAQIIPIERERTRKRQERDSVLSRSRQAVTALGE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEARVRELNLNRRAEINTERSDTLNELSVLDETLKRASDILNRTSLRAPVEGIVSVLNVN
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLGSVIAPGEEVARIVPADDNLEVEARVRPEDIAFIRLDLPAKVKLTSFDFTIYGALEGR
HHHHHCCCHHHHHEEECCCCCEEEEEEECCCCEEEEEECCCCEEEEEEEEEEEEEECCCE
VVRIGADAERDETTGETYFPIIVRTDSNALSRNGETHEIRTGMIASVDILTGERTVLDYL
EEEECCCCCCCCCCCCEEEEEEEEECCCHHHCCCCCCEECCCCEEEEEEECCCHHHHHHH
LKPLRKARLEALRER
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGTEWDFEASRRPRSTGRGLLTLVFLLVLLGLLVGAVSWASWARIEVMARAQGVVVPSG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCC
RARNVESLEGGIVRDILISEGDAVTQGQVLIRIDDIGAASTLGEITARRDAMLAKALRLE
CCCCHHHHCCCCEEHHHCCCCCCEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
AELLGEDAPDFSSLGLAEDHPLALREMALFDSRQAADLSQRTVLVSQVEQRSQEIEELGS
HHHHCCCCCCHHHCCCCCCCCHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
ALARIDESLELLDEEIALRTASGVVPRAQIIPIERERTRKRQERDSVLSRSRQAVTALGE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEARVRELNLNRRAEINTERSDTLNELSVLDETLKRASDILNRTSLRAPVEGIVSVLNVN
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLGSVIAPGEEVARIVPADDNLEVEARVRPEDIAFIRLDLPAKVKLTSFDFTIYGALEGR
HHHHHCCCHHHHHEEECCCCCEEEEEEECCCCEEEEEECCCCEEEEEEEEEEEEEECCCE
VVRIGADAERDETTGETYFPIIVRTDSNALSRNGETHEIRTGMIASVDILTGERTVLDYL
EEEECCCCCCCCCCCCEEEEEEEEECCCHHHCCCCCCEECCCCEEEEEEECCCHHHHHHH
LKPLRKARLEALRER
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]