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The map label for this gene is murA

Identifier: 110678405

GI number: 110678405

Start: 1025130

End: 1026398

Strand: Direct

Name: murA

Synonym: RD1_1065

Alternate gene names: 110678405

Gene position: 1025130-1026398 (Clockwise)

Preceding gene: 110678404

Following gene: 110678406

Centisome position: 24.8

GC content: 61.86

Gene sequence:

>1269_bases
ATGGATTCGATATTGGTCAAAGGGGGCGGCAGCCTGAAGGGGCAGATCCCGATCGCTGGTGCGAAAAACGCCTGTCTTGC
CCTTATGCCCGCAACACTGCTCTCCGAAGAGCCCCTGACGCTGACCAATGCACCGCGCCTGTCCGACATCCGCACCATGA
CGCAATTGCTGCAATCGCTGGGGGCGGAAGTGACCTCGCTGCAGGATGGCAAGGTGCTGGCCATGTCCTGTCACGGGGCG
ATCAACACGCGTGCGGAATATGACATCGTGCGCAAGATGCGCGCGTCCAACCTTGTGCTTGGCCCGCTTTTGGCGCGTGA
AGGGCATGCGCAGGTGTCCCTGCCCGGGGGGTGCGCAATCGGCGCGCGCCCCATGGATATTCACACGGATGGCTTGAGCC
AGATGGGTGCCGAGATAGAGTTGAAAGACGGCTATCTGCTGGCCAAGGCCAAGGGCGGACGGCTCAAAGGCGCTGTCATC
GACTTTCCCTTTGCCTCTGTGGGCGCGACTGAGAATATCGTGATGGCCGCGTCACTGGCGAAAGGCACCACCGTCATCAA
CAACGCCGCGCGCGAGCCCGAGATTGTGGACCTTGTTGAATGCCTGCGCGCCATGGGGGCACAAATCGAAGGCGAAGGGA
CCTCGACCATCTCGGTGCAGGGCGTTGACCGACTGGGCGGCACGACCCACCGCGTTGTGACCGACCGGATTGAGCTTGGC
ACCTACATGCTTGCCCCGGCGATCTGCGGTGGACAGGTCGAATTGCTGGGGGGGCGCATCAACCTGCTGGCTGCGTTTTG
CGACAAGCTGGATGCGGCGGGTGTCACAGTGACCGAAACCGAGAACGGGCTGAGCGTCGCCCGCGCAAATGGGGATATCC
GTGCGGTCGATGTCACGACGGAGCCATTTCCGGGGTTTCCCACCGATCTGCAGGCGCAGATGATGGCCCTGTTGTGCACC
GCCAAAGGGACCTCTGTTCTGGAAGAAAAGATATTCGAGAACCGCTTCATGCATGCGCCGGAGCTTATTCGCATGGGCGC
GGATATCGAGGTGCATGGCGGGACCGCGACCGTCAAGGGGGTCGACCGCCTGAAGGGGGCGCCGGTGATGGCCACTGATT
TGCGCGCGTCCGTTTCCCTGATCCTTGCGGGGCTTGCCGCTGAGGGCGAGACAAAAGTGTCCCGCGTCTATCATCTCGAC
CGTGGATATGAGCATGTGGTGCGCAAGCTCTCCGCTGTTGGGGCGCAGATCGAAAGGATCGCGGAATAA

Upstream 100 bases:

>100_bases
CTTGCGCGGCGCAAGTCTCAGTCGCGCGAACGGGCGCAGTCTGATGGGGAAACAGACAAAACGCCGGGCAGTTCCGGGCA
GGATAAGGACGCATAAGCGC

Downstream 100 bases:

>100_bases
TGACCGATGCACGTTTCGAAGACGGGCGTGAAGCGCCGTTGAACCTTGGTGCCGTGGATGTTGAAGACCTGAAGATCATG
TCGTCCCTGACGCAGGATGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDSILVKGGGSLKGQIPIAGAKNACLALMPATLLSEEPLTLTNAPRLSDIRTMTQLLQSLGAEVTSLQDGKVLAMSCHGA
INTRAEYDIVRKMRASNLVLGPLLAREGHAQVSLPGGCAIGARPMDIHTDGLSQMGAEIELKDGYLLAKAKGGRLKGAVI
DFPFASVGATENIVMAASLAKGTTVINNAAREPEIVDLVECLRAMGAQIEGEGTSTISVQGVDRLGGTTHRVVTDRIELG
TYMLAPAICGGQVELLGGRINLLAAFCDKLDAAGVTVTETENGLSVARANGDIRAVDVTTEPFPGFPTDLQAQMMALLCT
AKGTSVLEEKIFENRFMHAPELIRMGADIEVHGGTATVKGVDRLKGAPVMATDLRASVSLILAGLAAEGETKVSRVYHLD
RGYEHVVRKLSAVGAQIERIAE

Sequences:

>Translated_422_residues
MDSILVKGGGSLKGQIPIAGAKNACLALMPATLLSEEPLTLTNAPRLSDIRTMTQLLQSLGAEVTSLQDGKVLAMSCHGA
INTRAEYDIVRKMRASNLVLGPLLAREGHAQVSLPGGCAIGARPMDIHTDGLSQMGAEIELKDGYLLAKAKGGRLKGAVI
DFPFASVGATENIVMAASLAKGTTVINNAAREPEIVDLVECLRAMGAQIEGEGTSTISVQGVDRLGGTTHRVVTDRIELG
TYMLAPAICGGQVELLGGRINLLAAFCDKLDAAGVTVTETENGLSVARANGDIRAVDVTTEPFPGFPTDLQAQMMALLCT
AKGTSVLEEKIFENRFMHAPELIRMGADIEVHGGTATVKGVDRLKGAPVMATDLRASVSLILAGLAAEGETKVSRVYHLD
RGYEHVVRKLSAVGAQIERIAE
>Mature_422_residues
MDSILVKGGGSLKGQIPIAGAKNACLALMPATLLSEEPLTLTNAPRLSDIRTMTQLLQSLGAEVTSLQDGKVLAMSCHGA
INTRAEYDIVRKMRASNLVLGPLLAREGHAQVSLPGGCAIGARPMDIHTDGLSQMGAEIELKDGYLLAKAKGGRLKGAVI
DFPFASVGATENIVMAASLAKGTTVINNAAREPEIVDLVECLRAMGAQIEGEGTSTISVQGVDRLGGTTHRVVTDRIELG
TYMLAPAICGGQVELLGGRINLLAAFCDKLDAAGVTVTETENGLSVARANGDIRAVDVTTEPFPGFPTDLQAQMMALLCT
AKGTSVLEEKIFENRFMHAPELIRMGADIEVHGGTATVKGVDRLKGAPVMATDLRASVSLILAGLAAEGETKVSRVYHLD
RGYEHVVRKLSAVGAQIERIAE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=424, Percent_Identity=49.7641509433962, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_ROSDO (Q16BB7)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681412.1
- ProteinModelPortal:   Q16BB7
- SMR:   Q16BB7
- STRING:   Q16BB7
- GeneID:   4198308
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1065
- NMPDR:   fig|375451.6.peg.996
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q16BB7
- ProtClustDB:   PRK09369
- BioCyc:   RDEN375451:RD1_1065-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44272; Mature: 44272

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSILVKGGGSLKGQIPIAGAKNACLALMPATLLSEEPLTLTNAPRLSDIRTMTQLLQSL
CCCEEEECCCCCEEEEEECCCCCCHHEEHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHH
GAEVTSLQDGKVLAMSCHGAINTRAEYDIVRKMRASNLVLGPLLAREGHAQVSLPGGCAI
CCHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEHHHHCCCCCEEECCCCCEE
GARPMDIHTDGLSQMGAEIELKDGYLLAKAKGGRLKGAVIDFPFASVGATENIVMAASLA
CCCCCEEECCCHHHCCCEEEECCCEEEEECCCCEEEEEEEECCCHHCCCCCCEEEEEECC
KGTTVINNAAREPEIVDLVECLRAMGAQIEGEGTSTISVQGVDRLGGTTHRVVTDRIELG
CCCHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCCEEEEECHHHCCCCCHHEEHHHHHHC
TYMLAPAICGGQVELLGGRINLLAAFCDKLDAAGVTVTETENGLSVARANGDIRAVDVTT
HHEEHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEEEEEC
EPFPGFPTDLQAQMMALLCTAKGTSVLEEKIFENRFMHAPELIRMGADIEVHGGTATVKG
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCEEEECCEEEECH
VDRLKGAPVMATDLRASVSLILAGLAAEGETKVSRVYHLDRGYEHVVRKLSAVGAQIERI
HHHHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AE
CC
>Mature Secondary Structure
MDSILVKGGGSLKGQIPIAGAKNACLALMPATLLSEEPLTLTNAPRLSDIRTMTQLLQSL
CCCEEEECCCCCEEEEEECCCCCCHHEEHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHH
GAEVTSLQDGKVLAMSCHGAINTRAEYDIVRKMRASNLVLGPLLAREGHAQVSLPGGCAI
CCHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEHHHHCCCCCEEECCCCCEE
GARPMDIHTDGLSQMGAEIELKDGYLLAKAKGGRLKGAVIDFPFASVGATENIVMAASLA
CCCCCEEECCCHHHCCCEEEECCCEEEEECCCCEEEEEEEECCCHHCCCCCCEEEEEECC
KGTTVINNAAREPEIVDLVECLRAMGAQIEGEGTSTISVQGVDRLGGTTHRVVTDRIELG
CCCHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCCEEEEECHHHCCCCCHHEEHHHHHHC
TYMLAPAICGGQVELLGGRINLLAAFCDKLDAAGVTVTETENGLSVARANGDIRAVDVTT
HHEEHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEEEEEC
EPFPGFPTDLQAQMMALLCTAKGTSVLEEKIFENRFMHAPELIRMGADIEVHGGTATVKG
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCEEEECCEEEECH
VDRLKGAPVMATDLRASVSLILAGLAAEGETKVSRVYHLDRGYEHVVRKLSAVGAQIERI
HHHHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA