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The map label for this gene is des [H]

Identifier: 110678333

GI number: 110678333

Start: 951731

End: 952783

Strand: Direct

Name: des [H]

Synonym: RD1_0987

Alternate gene names: 110678333

Gene position: 951731-952783 (Clockwise)

Preceding gene: 110678332

Following gene: 110678335

Centisome position: 23.03

GC content: 59.07

Gene sequence:

>1053_bases
ATGACATCCGAAACTCCGTTTAGGGAGGCCACGCCGGTGTCGCCTTCGCCGGGCACTTCTGCGGGCTGGGTGCGTATCCT
CGCGCAATACAGAGAACCTAAGCTGGGCAGGTCGATTTTCGAAGTCATTGTGACGCTTGCACCCTTTATCGCCATATGGG
CCGTGGCATGGCTGCTGATCCCTGTCAGCTATCTGGCCAGTTTTGCGCTGGCCTGTCTGAACGGTCTCTTCCTTGTCAGG
CTGTTTTGCATTCAGCACGATTGCGGGCATGGGTCTTTCTTTGCGCATCGAGGCCTGAGCGACTGGCTGGGCCGGGGCTT
GGGCGTTCTGACGCTGACGCCCTATGATGTCTGGCGCAAGTCGCATTCCATGCATCATTCCGGTGCCGGCAATCTGGAAC
GGCGCGGCATTGGCGATGTCATGACCCTGACCGTTGATGAATACCATGCCCGTTCTGTTTTTGGCCGCCTGCGGTATCGG
GCCTATCGCAACCCGATTGTGCTTTTCCTGCTGGGGCCGGCCTATGTGTTTTACGTGGAAAACCGCCTGCCCCTGGGGCA
GATGGATGGGGGCTGGCGCGTCTGGGTCAGTTCTTTGGGCACGACGCTGCTGGCGGTTTTGCTGCTGGCGGCTATTGTCT
GGTTTGGTGGCTTGCTGCCTGTGTTGTTGATTTTTGTGCCGACCACCATGGTTGCGGCGACCTTGGGCGTGTGGCTGTTT
TACGTGCAGCACCAGTTTGAAGAGACACATTGGGATCAGCACGACGACTGGGACATGTACGATTCAGCGCTGCACGGATC
GTCCCATTACGTGATGCCCACATGGCTGCAGTGGTTTACCGCCAATATCGGCATCCACCATGTGCATCACCTTTATAGCC
GGATCCCGTTTTACCGCCTGACCGAAGTGCTGCGCGATCATCGCGAGTTGGCGCAGGCGCAACGCCTGAGTATTTCGGAA
AGCCTGGCGAGCGCGCGCCTGCATCTGTGGGACGAAAAGCAGCGCCGTCTGCTGTCATTCGCCGAGGCGCAGCGGGTCTA
CCGGGCCGCCTAG

Upstream 100 bases:

>100_bases
GGCATCGAAAACGCGGCTGTGTTGGGAGATGGTCAGGACCCTTGTGTGATCATCCCACTCAAGACAGATGTAAGAAACGA
TCGCGAAGAGGCAGACACCA

Downstream 100 bases:

>100_bases
CGCGTCTGAGGAAATATCTGAAACATCACGTATCACGCAGCGCGTTGAAATCTTTGATTCCAGTCAGCGTTGCGTGATTC
ATGTTTTTCGCATGACGCTT

Product: fatty acid desaturase, putative

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTSETPFREATPVSPSPGTSAGWVRILAQYREPKLGRSIFEVIVTLAPFIAIWAVAWLLIPVSYLASFALACLNGLFLVR
LFCIQHDCGHGSFFAHRGLSDWLGRGLGVLTLTPYDVWRKSHSMHHSGAGNLERRGIGDVMTLTVDEYHARSVFGRLRYR
AYRNPIVLFLLGPAYVFYVENRLPLGQMDGGWRVWVSSLGTTLLAVLLLAAIVWFGGLLPVLLIFVPTTMVAATLGVWLF
YVQHQFEETHWDQHDDWDMYDSALHGSSHYVMPTWLQWFTANIGIHHVHHLYSRIPFYRLTEVLRDHRELAQAQRLSISE
SLASARLHLWDEKQRRLLSFAEAQRVYRAA

Sequences:

>Translated_350_residues
MTSETPFREATPVSPSPGTSAGWVRILAQYREPKLGRSIFEVIVTLAPFIAIWAVAWLLIPVSYLASFALACLNGLFLVR
LFCIQHDCGHGSFFAHRGLSDWLGRGLGVLTLTPYDVWRKSHSMHHSGAGNLERRGIGDVMTLTVDEYHARSVFGRLRYR
AYRNPIVLFLLGPAYVFYVENRLPLGQMDGGWRVWVSSLGTTLLAVLLLAAIVWFGGLLPVLLIFVPTTMVAATLGVWLF
YVQHQFEETHWDQHDDWDMYDSALHGSSHYVMPTWLQWFTANIGIHHVHHLYSRIPFYRLTEVLRDHRELAQAQRLSISE
SLASARLHLWDEKQRRLLSFAEAQRVYRAA
>Mature_349_residues
TSETPFREATPVSPSPGTSAGWVRILAQYREPKLGRSIFEVIVTLAPFIAIWAVAWLLIPVSYLASFALACLNGLFLVRL
FCIQHDCGHGSFFAHRGLSDWLGRGLGVLTLTPYDVWRKSHSMHHSGAGNLERRGIGDVMTLTVDEYHARSVFGRLRYRA
YRNPIVLFLLGPAYVFYVENRLPLGQMDGGWRVWVSSLGTTLLAVLLLAAIVWFGGLLPVLLIFVPTTMVAATLGVWLFY
VQHQFEETHWDQHDDWDMYDSALHGSSHYVMPTWLQWFTANIGIHHVHHLYSRIPFYRLTEVLRDHRELAQAQRLSISES
LASARLHLWDEKQRRLLSFAEAQRVYRAA

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 39971; Mature: 39839

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSETPFREATPVSPSPGTSAGWVRILAQYREPKLGRSIFEVIVTLAPFIAIWAVAWLLI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PVSYLASFALACLNGLFLVRLFCIQHDCGHGSFFAHRGLSDWLGRGLGVLTLTPYDVWRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHCCCCEEEECHHHHHHH
SHSMHHSGAGNLERRGIGDVMTLTVDEYHARSVFGRLRYRAYRNPIVLFLLGPAYVFYVE
HHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEC
NRLPLGQMDGGWRVWVSSLGTTLLAVLLLAAIVWFGGLLPVLLIFVPTTMVAATLGVWLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVQHQFEETHWDQHDDWDMYDSALHGSSHYVMPTWLQWFTANIGIHHVHHLYSRIPFYRL
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
TEVLRDHRELAQAQRLSISESLASARLHLWDEKQRRLLSFAEAQRVYRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSETPFREATPVSPSPGTSAGWVRILAQYREPKLGRSIFEVIVTLAPFIAIWAVAWLLI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PVSYLASFALACLNGLFLVRLFCIQHDCGHGSFFAHRGLSDWLGRGLGVLTLTPYDVWRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHCCCCEEEECHHHHHHH
SHSMHHSGAGNLERRGIGDVMTLTVDEYHARSVFGRLRYRAYRNPIVLFLLGPAYVFYVE
HHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEC
NRLPLGQMDGGWRVWVSSLGTTLLAVLLLAAIVWFGGLLPVLLIFVPTTMVAATLGVWLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVQHQFEETHWDQHDDWDMYDSALHGSSHYVMPTWLQWFTANIGIHHVHHLYSRIPFYRL
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
TEVLRDHRELAQAQRLSISESLASARLHLWDEKQRRLLSFAEAQRVYRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]