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The map label for this gene is mlaA [H]

Identifier: 110678287

GI number: 110678287

Start: 910216

End: 910986

Strand: Reverse

Name: mlaA [H]

Synonym: RD1_0940

Alternate gene names: 110678287

Gene position: 910986-910216 (Counterclockwise)

Preceding gene: 110678293

Following gene: 110678286

Centisome position: 22.04

GC content: 56.94

Gene sequence:

>771_bases
TTGTTTGATTTTGCCCGCATCCAAAGACTTTTAAAACCCGCATCGTTTCTCCTGATGGCGCTCGCCCTGTCGGCCTGCGC
CACGTCTCAGGATCCGGCAACGCGCACCGATGGCATAAACGATCCCTACGAGTCGCAGAACAGGGCCATCCATCGATTCA
ACAAGGGTCTTGATAAAAACCTCGTCCGACCGGTTTCGAAGGGCTATGCAGCGGTTTTGCCGGTGGAAATACGCGACAGG
GTAAATGATTTTTCCGAAAACCTGTCGATGCCCGGTGTGGCGGTGAACAGCCTGTTGCAGGGGGATCTGCGCGGCGCTGG
CCTTGCGACCACGCGGTTTCTGATGAACACGACCATTGGGCTTGCAGGCTTCATCGACGCGGCCAGCGAATTGAACATCC
CGGAACATGACACCGATTTCGGCGAGACCTTGGCGGTTTGGGGCGTCGGCGAGGGGGCGTATATCGAACTGCCGATTTTC
GGGCCGTCAACGCAGCGTGACGCGGTGGGGTTTGTCACTGACTTCTTTACAAACCCGCTGACCTTTGCGACCATTGACAC
CAGCCCGGAACAATACATCCCGCCGACGGCGCGCGCGGGGTCGTGGCTCAATACACGCGACAAGATCAGCGGCACAATTG
ATTCCATCCTCTACGACAGCGCCGACAGCTACGCCCAATCGCGATCAGTTTACCTGCAAAACCGCCGATTTGAGCTTGAT
GGCGGTGGCGGTGCAGAAGAAGATCCCTATCTTGATCCTTACGCGGAATAA

Upstream 100 bases:

>100_bases
ATGGTGCGCACGTTCGAAAACGCCAGATTTACGACCGTTTCTTTCGGATCGCACAGACCATAGTTCCGCAAAAACGGATC
ACAGCCATAAGGTACTGCAA

Downstream 100 bases:

>100_bases
GAAAGAGAGCAGACATGCGGTTTGAACCATCCCGACGCAGTTTCCTTGCAGCAACAGCAGGCTTTTTGAGCTTGCTCGGA
GCGCCTGCCTTCGCACTGAG

Product: VacJ-like lipoprotein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MFDFARIQRLLKPASFLLMALALSACATSQDPATRTDGINDPYESQNRAIHRFNKGLDKNLVRPVSKGYAAVLPVEIRDR
VNDFSENLSMPGVAVNSLLQGDLRGAGLATTRFLMNTTIGLAGFIDAASELNIPEHDTDFGETLAVWGVGEGAYIELPIF
GPSTQRDAVGFVTDFFTNPLTFATIDTSPEQYIPPTARAGSWLNTRDKISGTIDSILYDSADSYAQSRSVYLQNRRFELD
GGGGAEEDPYLDPYAE

Sequences:

>Translated_256_residues
MFDFARIQRLLKPASFLLMALALSACATSQDPATRTDGINDPYESQNRAIHRFNKGLDKNLVRPVSKGYAAVLPVEIRDR
VNDFSENLSMPGVAVNSLLQGDLRGAGLATTRFLMNTTIGLAGFIDAASELNIPEHDTDFGETLAVWGVGEGAYIELPIF
GPSTQRDAVGFVTDFFTNPLTFATIDTSPEQYIPPTARAGSWLNTRDKISGTIDSILYDSADSYAQSRSVYLQNRRFELD
GGGGAEEDPYLDPYAE
>Mature_256_residues
MFDFARIQRLLKPASFLLMALALSACATSQDPATRTDGINDPYESQNRAIHRFNKGLDKNLVRPVSKGYAAVLPVEIRDR
VNDFSENLSMPGVAVNSLLQGDLRGAGLATTRFLMNTTIGLAGFIDAASELNIPEHDTDFGETLAVWGVGEGAYIELPIF
GPSTQRDAVGFVTDFFTNPLTFATIDTSPEQYIPPTARAGSWLNTRDKISGTIDSILYDSADSYAQSRSVYLQNRRFELD
GGGGAEEDPYLDPYAE

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=254, Percent_Identity=34.251968503937, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 27944; Mature: 27944

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDFARIQRLLKPASFLLMALALSACATSQDPATRTDGINDPYESQNRAIHRFNKGLDKN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
LVRPVSKGYAAVLPVEIRDRVNDFSENLSMPGVAVNSLLQGDLRGAGLATTRFLMNTTIG
HHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LAGFIDAASELNIPEHDTDFGETLAVWGVGEGAYIELPIFGPSTQRDAVGFVTDFFTNPL
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCE
TFATIDTSPEQYIPPTARAGSWLNTRDKISGTIDSILYDSADSYAQSRSVYLQNRRFELD
EEEEECCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEEEECCEEEEC
GGGGAEEDPYLDPYAE
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDFARIQRLLKPASFLLMALALSACATSQDPATRTDGINDPYESQNRAIHRFNKGLDKN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
LVRPVSKGYAAVLPVEIRDRVNDFSENLSMPGVAVNSLLQGDLRGAGLATTRFLMNTTIG
HHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LAGFIDAASELNIPEHDTDFGETLAVWGVGEGAYIELPIFGPSTQRDAVGFVTDFFTNPL
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCE
TFATIDTSPEQYIPPTARAGSWLNTRDKISGTIDSILYDSADSYAQSRSVYLQNRRFELD
EEEEECCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEEEECCEEEEC
GGGGAEEDPYLDPYAE
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]