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The map label for this gene is zntR [H]

Identifier: 110678265

GI number: 110678265

Start: 889215

End: 889652

Strand: Direct

Name: zntR [H]

Synonym: RD1_0918

Alternate gene names: 110678265

Gene position: 889215-889652 (Clockwise)

Preceding gene: 110678262

Following gene: 110678270

Centisome position: 21.51

GC content: 61.64

Gene sequence:

>438_bases
ATGTACCCCATCGGCACCCTGTCCAAACGCACCGGTACAAAGGTGCAGACGATCCGCTATTACGAACAGATCGGCCTGAT
GCAGGCACCGGAGCGCTCAAGTGGTGGGCGACGGCGCTATAACGATGCGGCGCTTGATCGCCTGTCTTTCATCCGTCACG
CGCGCCAGCTTGGCTTTACCCTTGATGCGATCCGCGAGTTGCTCGATCTGTCGGATAACCCGGCGCGCCCCTGTGCGCAG
GTCGATGAAATCGCGCATCGCCAGCTGCAAGAGGTGGAGCAGCGGATCGCGCGGCTTGAGGCCCTGCGCGTTGAACTGGA
ACGCATGTTGGATCAGTGTCGCAGGAATACTGTGGCGGAGTGCCGTGTGCTACAGGTGTTGGGGGATCATTCTGCCTGTC
TGTCCGATCACGGTGCGCCCCTGAGCCGCGAGGCGTGA

Upstream 100 bases:

>100_bases
CTCCGTTTCTTGACCCTGATATACGACCTCTAGTAACTATAGCTTCAAGAGGTATTTTCCCGGAACCGCAAATTTGTTTT
CTGCTCAGGAGAAAGCATCC

Downstream 100 bases:

>100_bases
CTTGTGGGGCTTGCCCCCTGTCATCTGCCTGACCGAAGAAACACCCAAGACGCTGCACCGCTTGGGACAAGAGGTATTTG
CGCAGTTGGCAACTCAGGGC

Product: HTH-type transcriptional regulator ZntR

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MYPIGTLSKRTGTKVQTIRYYEQIGLMQAPERSSGGRRRYNDAALDRLSFIRHARQLGFTLDAIRELLDLSDNPARPCAQ
VDEIAHRQLQEVEQRIARLEALRVELERMLDQCRRNTVAECRVLQVLGDHSACLSDHGAPLSREA

Sequences:

>Translated_145_residues
MYPIGTLSKRTGTKVQTIRYYEQIGLMQAPERSSGGRRRYNDAALDRLSFIRHARQLGFTLDAIRELLDLSDNPARPCAQ
VDEIAHRQLQEVEQRIARLEALRVELERMLDQCRRNTVAECRVLQVLGDHSACLSDHGAPLSREA
>Mature_145_residues
MYPIGTLSKRTGTKVQTIRYYEQIGLMQAPERSSGGRRRYNDAALDRLSFIRHARQLGFTLDAIRELLDLSDNPARPCAQ
VDEIAHRQLQEVEQRIARLEALRVELERMLDQCRRNTVAECRVLQVLGDHSACLSDHGAPLSREA

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=141, Percent_Identity=41.8439716312057, Blast_Score=101, Evalue=2e-23,
Organism=Escherichia coli, GI1786695, Length=124, Percent_Identity=33.8709677419355, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16543; Mature: 16543

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPIGTLSKRTGTKVQTIRYYEQIGLMQAPERSSGGRRRYNDAALDRLSFIRHARQLGFT
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCH
LDAIRELLDLSDNPARPCAQVDEIAHRQLQEVEQRIARLEALRVELERMLDQCRRNTVAE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CRVLQVLGDHSACLSDHGAPLSREA
HHHHHHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYPIGTLSKRTGTKVQTIRYYEQIGLMQAPERSSGGRRRYNDAALDRLSFIRHARQLGFT
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCH
LDAIRELLDLSDNPARPCAQVDEIAHRQLQEVEQRIARLEALRVELERMLDQCRRNTVAE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CRVLQVLGDHSACLSDHGAPLSREA
HHHHHHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]