Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 110678206

GI number: 110678206

Start: 832657

End: 833526

Strand: Direct

Name: livH [H]

Synonym: RD1_0855

Alternate gene names: 110678206

Gene position: 832657-833526 (Clockwise)

Preceding gene: 110678205

Following gene: 110678207

Centisome position: 20.15

GC content: 56.67

Gene sequence:

>870_bases
ATGGAACAGGTAATGGCCAACGGGGTCTATCTGGGATCTCAGTATGCGATGATCGCACTCGGATTGACCCTGATTTTCGC
CTTGATGAATGTTCTCAACTTTGCCCATGGGCAAATGTATGTCATTGGCGGCTTCGTCACCTATACATTTTACGGACAAT
GGGGCGTGCCCTTTGTGCTCGCGCTGTTCATGTCCTGCATGACATTGGCCATTATCGGCGCGCTGATCGAACGATACCTG
TTCGCCCCGGTGATCAAGGGCTCTGCCCGCGAAGAAAGCACGATGCTGCTCGCGGCGGGTATCGCGTTTCTGCTCGATGC
GCTGATCCTGTTGATCTTTGGCGAAAAACAGCGCGGCGTTCCCAAGATCGTGGACGGTGTCTTCAACTGGGATTTCCGCC
TGATCATGCCCTATGACCGCATATTGATCTGTGTGCTCGCCATTCTATCCATCGTCGCCTTCATCGCCCTGATGCAATAT
TCCAAGACGGGCCGCGCGCTGCGGGCGCTGGCGCAAGACCGCACCGCCGCCCAGTTGATGGGTGTCAACGTGGACCGCTA
TTCGATGATCGGTTTCGCGCTTGGTGCGATGCTGGCGGGTCTGGTTGGTGGCTTGCTGGTCACGATCACCGGCGTCAACC
TTGGCATGGGCGGTCCGACTTCGATCAAGGCCTTCATGATGGTGATGATCGGCGGTGCTGGTGTGATTTCGGGTGCGATC
TGGGGCGGGTTCATCCTCGGCTTCATGGAAGCCTTCGGCCTCGCTTACCTGTCGCAATACGGTGACATCACATATCTGCT
GATCTTTGTATCGCTGATGATTTTCCTCGCGATCCGGCCTCAGGGCCTGATGGGCAAACCCTGGGGGTGA

Upstream 100 bases:

>100_bases
TCGACTAAACCACTACACACGACATGCTGCTTCCGGCATCGCTCGGAAGCAGCTCCTGCCCGACGGATAGGTCGGGGTTA
ACCATAGAAAGAAAGTGCTC

Downstream 100 bases:

>100_bases
TGGCGTCATGAACTTTTCAAAAATCCAAATCCTCGGCGTTCTGGTCTTTCTGGCCGTGGTCTTTGTGGGTGTGCCTGTCT
TCATCGCGGCAACGGGCCGG

Product: branched-chain amino acid ABC transporter, permease protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MEQVMANGVYLGSQYAMIALGLTLIFALMNVLNFAHGQMYVIGGFVTYTFYGQWGVPFVLALFMSCMTLAIIGALIERYL
FAPVIKGSAREESTMLLAAGIAFLLDALILLIFGEKQRGVPKIVDGVFNWDFRLIMPYDRILICVLAILSIVAFIALMQY
SKTGRALRALAQDRTAAQLMGVNVDRYSMIGFALGAMLAGLVGGLLVTITGVNLGMGGPTSIKAFMMVMIGGAGVISGAI
WGGFILGFMEAFGLAYLSQYGDITYLLIFVSLMIFLAIRPQGLMGKPWG

Sequences:

>Translated_289_residues
MEQVMANGVYLGSQYAMIALGLTLIFALMNVLNFAHGQMYVIGGFVTYTFYGQWGVPFVLALFMSCMTLAIIGALIERYL
FAPVIKGSAREESTMLLAAGIAFLLDALILLIFGEKQRGVPKIVDGVFNWDFRLIMPYDRILICVLAILSIVAFIALMQY
SKTGRALRALAQDRTAAQLMGVNVDRYSMIGFALGAMLAGLVGGLLVTITGVNLGMGGPTSIKAFMMVMIGGAGVISGAI
WGGFILGFMEAFGLAYLSQYGDITYLLIFVSLMIFLAIRPQGLMGKPWG
>Mature_289_residues
MEQVMANGVYLGSQYAMIALGLTLIFALMNVLNFAHGQMYVIGGFVTYTFYGQWGVPFVLALFMSCMTLAIIGALIERYL
FAPVIKGSAREESTMLLAAGIAFLLDALILLIFGEKQRGVPKIVDGVFNWDFRLIMPYDRILICVLAILSIVAFIALMQY
SKTGRALRALAQDRTAAQLMGVNVDRYSMIGFALGAMLAGLVGGLLVTITGVNLGMGGPTSIKAFMMVMIGGAGVISGAI
WGGFILGFMEAFGLAYLSQYGDITYLLIFVSLMIFLAIRPQGLMGKPWG

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=299, Percent_Identity=33.4448160535117, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 31203; Mature: 31203

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVMANGVYLGSQYAMIALGLTLIFALMNVLNFAHGQMYVIGGFVTYTFYGQWGVPFVL
CCCHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHEEEEEEECCCCHHHHH
ALFMSCMTLAIIGALIERYLFAPVIKGSAREESTMLLAAGIAFLLDALILLIFGEKQRGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKIVDGVFNWDFRLIMPYDRILICVLAILSIVAFIALMQYSKTGRALRALAQDRTAAQLM
HHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVNVDRYSMIGFALGAMLAGLVGGLLVTITGVNLGMGGPTSIKAFMMVMIGGAGVISGAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
WGGFILGFMEAFGLAYLSQYGDITYLLIFVSLMIFLAIRPQGLMGKPWG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEQVMANGVYLGSQYAMIALGLTLIFALMNVLNFAHGQMYVIGGFVTYTFYGQWGVPFVL
CCCHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHEEEEEEECCCCHHHHH
ALFMSCMTLAIIGALIERYLFAPVIKGSAREESTMLLAAGIAFLLDALILLIFGEKQRGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKIVDGVFNWDFRLIMPYDRILICVLAILSIVAFIALMQYSKTGRALRALAQDRTAAQLM
HHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVNVDRYSMIGFALGAMLAGLVGGLLVTITGVNLGMGGPTSIKAFMMVMIGGAGVISGAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
WGGFILGFMEAFGLAYLSQYGDITYLLIFVSLMIFLAIRPQGLMGKPWG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]