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The map label for this gene is crp [C]

Identifier: 110678172

GI number: 110678172

Start: 798543

End: 799160

Strand: Direct

Name: crp [C]

Synonym: RD1_0816

Alternate gene names: 110678172

Gene position: 798543-799160 (Clockwise)

Preceding gene: 110678171

Following gene: 110678176

Centisome position: 19.32

GC content: 57.28

Gene sequence:

>618_bases
TTGCCGAAAACCGGATTTTTGGCCCATGCCTCGCAGAAACTGTCTGATCTGTTGAATTCCGTTTCGACTGAAGTCGACCT
GAGCGAAGGTGAAGTGCTGTTCGAGCAGGGCGACACCGGTGACGCGCTTTACGCCATTGTGTCGGGAAGTCTGGAATTCA
GCATAATATCACGGGAAGGGCGCAAGCTGTCCTTGGATGTGATGCGCCCCGGGGCGCTGTTTGGTGAGATTGCGCTGTTT
GACCCCGGTACGCGTACAGCTACGGTCACCGCGCTTGAGCACAGCCGCGTGCGGGGAGTGAAAAACGCGGATGTTCTGGC
TGCCATTCGCAAGTCGCCAGAGTTGGGGATAGATCTTATTCAACTGGCTGGGGTGCGGCTGCGTTGGATGAGCAGCCAGT
TGAACGAGCAGGTATTCCTGCCCATGCCCGCCCGGCTCGCGCGTAAAATTCTCTACCTTACGATAGATGGATCAGATGAC
CTTGGCCTTTTGAACCTGTCTCAGGCTGAACTGGCAGAATTCGTCGGCGCGACGCGGGAGGCGGTATCCAAAACACTGTC
CCTTTGGAAACGTGCCGGTGTCATTGACGCGTCGCGGGGGGGGGCTGCGGGTTATTGA

Upstream 100 bases:

>100_bases
GGTTTCATACGTTAAACAGGACGCCTGATCACACAGGTAAAAGATACGTCTATGTAAAGACGCAGCAATCAAGGATTGGA
GTACGATGGACAGCCCGGAG

Downstream 100 bases:

>100_bases
CCGCAATGCCCTGCAGGTCATGGCGGATCTGCATCATATTTGATGTGCCCATGTGATGAGGGTCACAGACGAACCGTTAC
ATTTACGCAATATTGAACTG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP Family Transcriptional Regulator; CAMP-Dependent Transcriptional Regulator; Catabolite Gene Activator; Transcription Regulator; CRP Protein; Transcription Regulator Crp Family; Transcriptional Regulatory Protein; Regulatory Protein; Transcriptional Regulator Crp; Global Nitrogen Regulator NtcA; Anaerobic Regulatory Protein; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MPKTGFLAHASQKLSDLLNSVSTEVDLSEGEVLFEQGDTGDALYAIVSGSLEFSIISREGRKLSLDVMRPGALFGEIALF
DPGTRTATVTALEHSRVRGVKNADVLAAIRKSPELGIDLIQLAGVRLRWMSSQLNEQVFLPMPARLARKILYLTIDGSDD
LGLLNLSQAELAEFVGATREAVSKTLSLWKRAGVIDASRGGAAGY

Sequences:

>Translated_205_residues
MPKTGFLAHASQKLSDLLNSVSTEVDLSEGEVLFEQGDTGDALYAIVSGSLEFSIISREGRKLSLDVMRPGALFGEIALF
DPGTRTATVTALEHSRVRGVKNADVLAAIRKSPELGIDLIQLAGVRLRWMSSQLNEQVFLPMPARLARKILYLTIDGSDD
LGLLNLSQAELAEFVGATREAVSKTLSLWKRAGVIDASRGGAAGY
>Mature_204_residues
PKTGFLAHASQKLSDLLNSVSTEVDLSEGEVLFEQGDTGDALYAIVSGSLEFSIISREGRKLSLDVMRPGALFGEIALFD
PGTRTATVTALEHSRVRGVKNADVLAAIRKSPELGIDLIQLAGVRLRWMSSQLNEQVFLPMPARLARKILYLTIDGSDDL
GLLNLSQAELAEFVGATREAVSKTLSLWKRAGVIDASRGGAAGY

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789756, Length=170, Percent_Identity=27.0588235294118, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 22017; Mature: 21885

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTGFLAHASQKLSDLLNSVSTEVDLSEGEVLFEQGDTGDALYAIVSGSLEFSIISREG
CCCCCCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCEEEEEEECCEEEEEEECCC
RKLSLDVMRPGALFGEIALFDPGTRTATVTALEHSRVRGVKNADVLAAIRKSPELGIDLI
CEEEEEEECCCCCEEEEEEECCCCCEEEEEEEHHHHHCCCCCHHHHHHHHCCCCCCHHHH
QLAGVRLRWMSSQLNEQVFLPMPARLARKILYLTIDGSDDLGLLNLSQAELAEFVGATRE
HHCCHHHEEHHHHCCCEEECCCCHHHCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHH
AVSKTLSLWKRAGVIDASRGGAAGY
HHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PKTGFLAHASQKLSDLLNSVSTEVDLSEGEVLFEQGDTGDALYAIVSGSLEFSIISREG
CCCCCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCEEEEEEECCEEEEEEECCC
RKLSLDVMRPGALFGEIALFDPGTRTATVTALEHSRVRGVKNADVLAAIRKSPELGIDLI
CEEEEEEECCCCCEEEEEEECCCCCEEEEEEEHHHHHCCCCCHHHHHHHHCCCCCCHHHH
QLAGVRLRWMSSQLNEQVFLPMPARLARKILYLTIDGSDDLGLLNLSQAELAEFVGATRE
HHCCHHHEEHHHHCCCEEECCCCHHHCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHH
AVSKTLSLWKRAGVIDASRGGAAGY
HHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA