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The map label for this gene is livH [H]

Identifier: 110678079

GI number: 110678079

Start: 682582

End: 683571

Strand: Direct

Name: livH [H]

Synonym: RD1_0704

Alternate gene names: 110678079

Gene position: 682582-683571 (Clockwise)

Preceding gene: 110678078

Following gene: 110678081

Centisome position: 16.52

GC content: 56.46

Gene sequence:

>990_bases
ATGCCTGAACAACTGCTTTGGACCGCCGAGGTTTTTCTGAACGGGCTGATGGCGGGCGTCCTTTATGCGCTCGTGGCGCT
GGGCTTTGTGCTGATCTACAAGGCCAGCGGAATTTTCAACTTTGCCCAAGGCGTCATGGCGCTTTTCGCGGCGATGACGC
TTTACGGCATCATGAATGGTCAGGTGCCCTTTGCGCATCTGATCAATGCGATTTTCGGCACGGAGATCCATTATTTCGGC
TGGAATGTACCGGCGCTGGCGGCAATTTTCCTGACGATGTGCGTCATGGTGCTGTTCAGTTGGCTGGTGCAGCGATACAT
CTTCCGGTTTTTGGTCGGGCAGGAGCCGATCATCCTGTTCATGGCGACCATCGGGCTGGCCTATTTCCTCGAAGGCGTTG
GGGATTTGATGTGGGGCTCAGACATCAAAACGCTTGAAGTCGGCCTGCCGCAGGGCATCAACGAAACCATTGACGCCGTG
ACTTTCGAGGCCTTTGGGTACGGGTTTTTCATCGATAATCTGGATATTGTGGCCTCGGTCGTGGCCGCCATTCTGGTGCT
GGGCCTCGTGTTGTTTGCGCAATACACCAAGCAGGGCCGGGCCATGCGGGCGGTGGCGGATGATCATCAGGCGGCCTTGT
CCGTGGGTGTTTCGCTCAATTTCATCTGGATTCTGGTGTGGTCGCTGGCGGGTTTCGTGGCCCTTGTTGCCGGTATCATG
TGGGGGGCGAAATCGGGTGTGCAGTTTTCGCTGTCCCTTATTGCGCTCAAAGCGCTGCCGGTGCTGATGCTTGGCGGTTT
CACCTCGATCCCCGGCGCGATCGTTGGCGGTCTGATCATCGGGGTTGGTGAAAAACTGTTCGAGTTTCTGATTGGTCAGC
CGTACCTTGGCGGCGCCACGGAAAACTGGTTTGCCTATATGTTGGCGCTGGTATTCTTGCTGTTCCGGCCTCAGGGCCTC
TTTGGGGAGAAGATCATTGAGCGCGTTTGA

Upstream 100 bases:

>100_bases
TTGGGGCGTCGGTATCACGTCGGTATGACGTCGGTATTGCGTCGGTGCGGCGCTTCAACCGGCAAGCCCGCTCTCATTCG
CTCACGCAGGGAGACTTCCG

Downstream 100 bases:

>100_bases
CGTCATGGGGGCGCACCGGGGCGCGCAGCGTCAGTCGTCCTTGACCTGCAACAAGGCCACGCTGAGCGCTGCGAGGATCG
TCACGCCCAGGGTCAGCGCC

Product: branched-chain amino acid ABC transporter, permease protein, putative

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPEQLLWTAEVFLNGLMAGVLYALVALGFVLIYKASGIFNFAQGVMALFAAMTLYGIMNGQVPFAHLINAIFGTEIHYFG
WNVPALAAIFLTMCVMVLFSWLVQRYIFRFLVGQEPIILFMATIGLAYFLEGVGDLMWGSDIKTLEVGLPQGINETIDAV
TFEAFGYGFFIDNLDIVASVVAAILVLGLVLFAQYTKQGRAMRAVADDHQAALSVGVSLNFIWILVWSLAGFVALVAGIM
WGAKSGVQFSLSLIALKALPVLMLGGFTSIPGAIVGGLIIGVGEKLFEFLIGQPYLGGATENWFAYMLALVFLLFRPQGL
FGEKIIERV

Sequences:

>Translated_329_residues
MPEQLLWTAEVFLNGLMAGVLYALVALGFVLIYKASGIFNFAQGVMALFAAMTLYGIMNGQVPFAHLINAIFGTEIHYFG
WNVPALAAIFLTMCVMVLFSWLVQRYIFRFLVGQEPIILFMATIGLAYFLEGVGDLMWGSDIKTLEVGLPQGINETIDAV
TFEAFGYGFFIDNLDIVASVVAAILVLGLVLFAQYTKQGRAMRAVADDHQAALSVGVSLNFIWILVWSLAGFVALVAGIM
WGAKSGVQFSLSLIALKALPVLMLGGFTSIPGAIVGGLIIGVGEKLFEFLIGQPYLGGATENWFAYMLALVFLLFRPQGL
FGEKIIERV
>Mature_328_residues
PEQLLWTAEVFLNGLMAGVLYALVALGFVLIYKASGIFNFAQGVMALFAAMTLYGIMNGQVPFAHLINAIFGTEIHYFGW
NVPALAAIFLTMCVMVLFSWLVQRYIFRFLVGQEPIILFMATIGLAYFLEGVGDLMWGSDIKTLEVGLPQGINETIDAVT
FEAFGYGFFIDNLDIVASVVAAILVLGLVLFAQYTKQGRAMRAVADDHQAALSVGVSLNFIWILVWSLAGFVALVAGIMW
GAKSGVQFSLSLIALKALPVLMLGGFTSIPGAIVGGLIIGVGEKLFEFLIGQPYLGGATENWFAYMLALVFLLFRPQGLF
GEKIIERV

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=331, Percent_Identity=27.4924471299094, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35756; Mature: 35625

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEQLLWTAEVFLNGLMAGVLYALVALGFVLIYKASGIFNFAQGVMALFAAMTLYGIMNG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
QVPFAHLINAIFGTEIHYFGWNVPALAAIFLTMCVMVLFSWLVQRYIFRFLVGQEPIILF
CCCHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
MATIGLAYFLEGVGDLMWGSDIKTLEVGLPQGINETIDAVTFEAFGYGFFIDNLDIVASV
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAILVLGLVLFAQYTKQGRAMRAVADDHQAALSVGVSLNFIWILVWSLAGFVALVAGIM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
WGAKSGVQFSLSLIALKALPVLMLGGFTSIPGAIVGGLIIGVGEKLFEFLIGQPYLGGAT
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ENWFAYMLALVFLLFRPQGLFGEKIIERV
HHHHHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
PEQLLWTAEVFLNGLMAGVLYALVALGFVLIYKASGIFNFAQGVMALFAAMTLYGIMNG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC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HHHHHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]