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The map label for this gene is dapB

Identifier: 110678027

GI number: 110678027

Start: 629629

End: 630447

Strand: Direct

Name: dapB

Synonym: RD1_0650

Alternate gene names: 110678027

Gene position: 629629-630447 (Clockwise)

Preceding gene: 110678015

Following gene: 110678028

Centisome position: 15.23

GC content: 63.74

Gene sequence:

>819_bases
ATGACGACACCCATGAAGATTGCGATTACAGGTGTGTCCGGACGCATGGGCCGGATGCTGGTGGACACCATCGATACCTC
CGATGCCGTGACCCTGTCCGCCGCATTGGAACGACCCGGACATGACTGGATCGGGCGCGATCTGGGTCTGGCGCTGGGCG
GTACGGAACGCGGCGTTCTGGTCAGCGATGACATCGACAGCGCGCTGGCGGACAGTGAGGCGGTGATTGATTTCACCAGC
CCCGCCGCAACGATCCGTTTTGCGCAGGCCGCAGCGCGGGTTGGCGCCATTCATGTTATTGGCACCACCGGGATGACAGA
ACAGGAGATCGCGCAGATCGATGCGCAGGCGGCGGGTGCGGTGATCGTGCGCGCGGGAAACATGAGCCTTGGCGTGAACC
TGCTGGTGCAGCTGACCAAACGCGTGGCGGCGGCGCTGGACGAAGATTTTGACATTGAAGTCATTGAATCTCACCACAAT
CAGAAAGTCGATGCCCCCTCAGGCACCGCGCTGATGCTGGGGGAGGCGGCGGCAGAGGGGCGAGGGGTGTCGCTCGATGC
GGTGTCTGACCGGGGGCGCGATGGTCTGACCGGCGCGCGCCAAAAGGGGGACATCGGTTTTGTTTCTGTCCGCGGGGGCG
ATATCGTCGGGGAACATGACGTTCTGTTCGCAGCGCAGGGGGAGCGGATCACCCTGCGTCATGTGGCCTCTGACCGTTCT
GTCTTTGCGCGCGGTGCGCTCAAGGCGGCGTTGTGGGCGCGGCATCGTGCGCCCGGAGCCTATGACATGCTGGATGTGCT
GGGGCTGAAGGACGGCTGA

Upstream 100 bases:

>100_bases
GTTCTTTCCCATAAATCTCATTTACGCCCTTGCGTGCCCTTTGCCAAGCGGAGCTACGCAGGCTAAGACGCCCTGTGAGC
GACAGATGCAGGAGGGCGCC

Downstream 100 bases:

>100_bases
TCGGTCGCGGAACTTTTTCACACGAAAAATGATCTGATCCGATGGGTTCTGCGTACCGTTAGAAAGCAATTCAAGTGGAG
TAAGAACACAATGCGCATTG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTTPMKIAITGVSGRMGRMLVDTIDTSDAVTLSAALERPGHDWIGRDLGLALGGTERGVLVSDDIDSALADSEAVIDFTS
PAATIRFAQAAARVGAIHVIGTTGMTEQEIAQIDAQAAGAVIVRAGNMSLGVNLLVQLTKRVAAALDEDFDIEVIESHHN
QKVDAPSGTALMLGEAAAEGRGVSLDAVSDRGRDGLTGARQKGDIGFVSVRGGDIVGEHDVLFAAQGERITLRHVASDRS
VFARGALKAALWARHRAPGAYDMLDVLGLKDG

Sequences:

>Translated_272_residues
MTTPMKIAITGVSGRMGRMLVDTIDTSDAVTLSAALERPGHDWIGRDLGLALGGTERGVLVSDDIDSALADSEAVIDFTS
PAATIRFAQAAARVGAIHVIGTTGMTEQEIAQIDAQAAGAVIVRAGNMSLGVNLLVQLTKRVAAALDEDFDIEVIESHHN
QKVDAPSGTALMLGEAAAEGRGVSLDAVSDRGRDGLTGARQKGDIGFVSVRGGDIVGEHDVLFAAQGERITLRHVASDRS
VFARGALKAALWARHRAPGAYDMLDVLGLKDG
>Mature_271_residues
TTPMKIAITGVSGRMGRMLVDTIDTSDAVTLSAALERPGHDWIGRDLGLALGGTERGVLVSDDIDSALADSEAVIDFTSP
AATIRFAQAAARVGAIHVIGTTGMTEQEIAQIDAQAAGAVIVRAGNMSLGVNLLVQLTKRVAAALDEDFDIEVIESHHNQ
KVDAPSGTALMLGEAAAEGRGVSLDAVSDRGRDGLTGARQKGDIGFVSVRGGDIVGEHDVLFAAQGERITLRHVASDRSV
FARGALKAALWARHRAPGAYDMLDVLGLKDG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=43.4456928838951, Blast_Score=194, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_ROSDO (Q16CE5)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681034.1
- ProteinModelPortal:   Q16CE5
- SMR:   Q16CE5
- STRING:   Q16CE5
- GeneID:   4198084
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_0650
- NMPDR:   fig|375451.6.peg.612
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   Q16CE5
- ProtClustDB:   PRK00048
- BioCyc:   RDEN375451:RD1_0650-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28301; Mature: 28170

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPMKIAITGVSGRMGRMLVDTIDTSDAVTLSAALERPGHDWIGRDLGLALGGTERGVL
CCCCEEEEEEECCCCCCCEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCEEECCCCCCEE
VSDDIDSALADSEAVIDFTSPAATIRFAQAAARVGAIHVIGTTGMTEQEIAQIDAQAAGA
EECCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCE
VIVRAGNMSLGVNLLVQLTKRVAAALDEDFDIEVIESHHNQKVDAPSGTALMLGEAAAEG
EEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCC
RGVSLDAVSDRGRDGLTGARQKGDIGFVSVRGGDIVGEHDVLFAAQGERITLRHVASDRS
CCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCEECCCCEEEEECCCEEEEEEECCCCH
VFARGALKAALWARHRAPGAYDMLDVLGLKDG
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TTPMKIAITGVSGRMGRMLVDTIDTSDAVTLSAALERPGHDWIGRDLGLALGGTERGVL
CCCEEEEEEECCCCCCCEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCEEECCCCCCEE
VSDDIDSALADSEAVIDFTSPAATIRFAQAAARVGAIHVIGTTGMTEQEIAQIDAQAAGA
EECCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCE
VIVRAGNMSLGVNLLVQLTKRVAAALDEDFDIEVIESHHNQKVDAPSGTALMLGEAAAEG
EEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCC
RGVSLDAVSDRGRDGLTGARQKGDIGFVSVRGGDIVGEHDVLFAAQGERITLRHVASDRS
CCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCEECCCCEEEEECCCEEEEEEECCCCH
VFARGALKAALWARHRAPGAYDMLDVLGLKDG
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA