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The map label for this gene is ahpC [C]

Identifier: 110678013

GI number: 110678013

Start: 616042

End: 616695

Strand: Direct

Name: ahpC [C]

Synonym: RD1_0634

Alternate gene names: 110678013

Gene position: 616042-616695 (Clockwise)

Preceding gene: 110678011

Following gene: 110678015

Centisome position: 14.91

GC content: 56.27

Gene sequence:

>654_bases
ATGGGCTTGCGCATCAACGATACTGTTCCCGATTTCACAGCGGAAACTGACCACGGAACGATCCAGTTTCATGACTGGAT
TGGCGACAGCTGGGCGATTTTATTCTCGCACCCAAAGGATTTCACACCGGTTTGCACCACGGAATTCGGCGCCGTCGCGC
AACTGGCCGATGAGTGGGAAAAACGCGGCACCAAGGTGATCGGCGTTTCGGTTGATGGCGTTGAGGATCACAAGAAGTGG
AAAGGTGATATCGAACATGTCGCGGGCACAACCGCTGGCTTTCCGATCATCGCTGACGAAGGGCTCGCCGTGTCTAAAGC
CTTTGACATGTTGCCGGCGGAGGCCTATCTGCCCGACGGCCGCACACCTGCTGACAGCGCAACGGTGCGGTCGGTCTTCA
TCATCGGGCCGGACAAGCAGCTTAAACTGTCGATGACATACCCGATGACCGTTGGTCGTAATTTTGCCGAAGTGCTGCGC
GCCCTTGATGGTTTGCAAATGTCGACCGGCAAAGGTGTTGCGACCCCCGCAAACTGGGTTCCGGGTGAGGATGTGATCAT
TCCGCCATCGGTGTCGGATGAAGACGCCAAGGCGAAATTCGGCGACTTTGAAACCGTCCTGCCCTATTTGCGCAAAACCA
AAGCGCCAAGCTGA

Upstream 100 bases:

>100_bases
GTCACTGTCGCGTGTGAACGGCAATAGAGGGGGTGTCACTGGCCGAGATAAGTATTAGATGTGCGCAGAATGAATGACAG
CACTGCACCGGAGGATTTTT

Downstream 100 bases:

>100_bases
GAAACTGGCCCGTGCCCCGGGTTACGCAGGGTGCGGGCCTGCCACTTGAGCGTCATGCGAAAAACCTGAAGCACGTAACG
CTGCCTGAAATCAAAGATTT

Product: anti-oxidant AhpCTSA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MGLRINDTVPDFTAETDHGTIQFHDWIGDSWAILFSHPKDFTPVCTTEFGAVAQLADEWEKRGTKVIGVSVDGVEDHKKW
KGDIEHVAGTTAGFPIIADEGLAVSKAFDMLPAEAYLPDGRTPADSATVRSVFIIGPDKQLKLSMTYPMTVGRNFAEVLR
ALDGLQMSTGKGVATPANWVPGEDVIIPPSVSDEDAKAKFGDFETVLPYLRKTKAPS

Sequences:

>Translated_217_residues
MGLRINDTVPDFTAETDHGTIQFHDWIGDSWAILFSHPKDFTPVCTTEFGAVAQLADEWEKRGTKVIGVSVDGVEDHKKW
KGDIEHVAGTTAGFPIIADEGLAVSKAFDMLPAEAYLPDGRTPADSATVRSVFIIGPDKQLKLSMTYPMTVGRNFAEVLR
ALDGLQMSTGKGVATPANWVPGEDVIIPPSVSDEDAKAKFGDFETVLPYLRKTKAPS
>Mature_216_residues
GLRINDTVPDFTAETDHGTIQFHDWIGDSWAILFSHPKDFTPVCTTEFGAVAQLADEWEKRGTKVIGVSVDGVEDHKKWK
GDIEHVAGTTAGFPIIADEGLAVSKAFDMLPAEAYLPDGRTPADSATVRSVFIIGPDKQLKLSMTYPMTVGRNFAEVLRA
LDGLQMSTGKGVATPANWVPGEDVIIPPSVSDEDAKAKFGDFETVLPYLRKTKAPS

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=226, Percent_Identity=46.9026548672566, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI32189392, Length=202, Percent_Identity=30.6930693069307, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI4505591, Length=191, Percent_Identity=28.2722513089005, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI32455266, Length=191, Percent_Identity=28.2722513089005, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI32455264, Length=191, Percent_Identity=28.2722513089005, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI5453549, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI5802974, Length=171, Percent_Identity=29.2397660818713, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32483377, Length=171, Percent_Identity=29.2397660818713, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786822, Length=159, Percent_Identity=29.559748427673, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=198, Percent_Identity=43.4343434343434, Blast_Score=173, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI193204376, Length=169, Percent_Identity=29.585798816568, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32565831, Length=169, Percent_Identity=29.585798816568, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17554494, Length=187, Percent_Identity=28.8770053475936, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319407, Length=216, Percent_Identity=53.7037037037037, Blast_Score=234, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI6323613, Length=171, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=159, Percent_Identity=27.0440251572327, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24581278, Length=222, Percent_Identity=46.8468468468468, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17975518, Length=202, Percent_Identity=46.039603960396, Blast_Score=183, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24652434, Length=202, Percent_Identity=46.039603960396, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24652436, Length=202, Percent_Identity=46.039603960396, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI17157991, Length=176, Percent_Identity=30.6818181818182, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641739, Length=176, Percent_Identity=30.6818181818182, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17738015, Length=206, Percent_Identity=28.6407766990291, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357347, Length=198, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24656348, Length=169, Percent_Identity=29.585798816568, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17864676, Length=169, Percent_Identity=29.585798816568, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23521; Mature: 23390

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRINDTVPDFTAETDHGTIQFHDWIGDSWAILFSHPKDFTPVCTTEFGAVAQLADEWE
CCEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
KRGTKVIGVSVDGVEDHKKWKGDIEHVAGTTAGFPIIADEGLAVSKAFDMLPAEAYLPDG
HCCCEEEEEEECCCHHHHHHHCHHHHHCCCCCCCCEEECCCCCHHHHHHHCCCHHCCCCC
RTPADSATVRSVFIIGPDKQLKLSMTYPMTVGRNFAEVLRALDGLQMSTGKGVATPANWV
CCCCCCCEEEEEEEECCCCEEEEEEECCHHHCCCHHHHHHHHCCCEECCCCCCCCCCCCC
PGEDVIIPPSVSDEDAKAKFGDFETVLPYLRKTKAPS
CCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GLRINDTVPDFTAETDHGTIQFHDWIGDSWAILFSHPKDFTPVCTTEFGAVAQLADEWE
CEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
KRGTKVIGVSVDGVEDHKKWKGDIEHVAGTTAGFPIIADEGLAVSKAFDMLPAEAYLPDG
HCCCEEEEEEECCCHHHHHHHCHHHHHCCCCCCCCEEECCCCCHHHHHHHCCCHHCCCCC
RTPADSATVRSVFIIGPDKQLKLSMTYPMTVGRNFAEVLRALDGLQMSTGKGVATPANWV
CCCCCCCEEEEEEEECCCCEEEEEEECCHHHCCCHHHHHHHHCCCEECCCCCCCCCCCCC
PGEDVIIPPSVSDEDAKAKFGDFETVLPYLRKTKAPS
CCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]