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The map label for this gene is soxA [H]

Identifier: 110677986

GI number: 110677986

Start: 588521

End: 590956

Strand: Direct

Name: soxA [H]

Synonym: RD1_0607

Alternate gene names: 110677986

Gene position: 588521-590956 (Clockwise)

Preceding gene: 110677985

Following gene: 110677988

Centisome position: 14.24

GC content: 59.28

Gene sequence:

>2436_bases
ATGAAATCACGCACGAAGGTTGCGGTCATCGGCGGTGGTATAGCCGGGTGCTCAACGCTTTATCACCTGACCGAAGAGGG
TTGGTCAGACGTGGTTCTGATCGAACGGGACGAGTTGACCTCGGGCACCACATGGCACTCAGCGGCGCAGGTGACGAACT
TCGGGATGAACCAGACGATGGTGGGTCTCAAGACCCATTCGATCCGGCTCTACAAGAAACTGCGTGATGATCCCGACTAT
CCTGTTGGCTATCACCACGGCGACGGCGGCATCCGGCTGGCCAATACGCCCGAACAAATGCAGGCCTACAGGCATTTCGC
ATCCATGGCGCGGGGCATGGGAACCGACTTTGAGGTGATTGATGCCAGAGAATGCGCCCGCCGCCATCCGCTGATCTCAA
CGGACAACCTGCTGGGCGGTCTGTGGGATGGTGAAGATGGCGATATTGATCCGGCCCAGTTGTGTCAGGCACTGGCCTTT
CACGCACGCAAGGCCGGCGCGGAGGTCTACCGCCATACCAACGTCACGGCGCTGACGCAGCATGCAGATGACACCTGGAC
GGTCGAGACGGACAAAGGCCGGATTGATGCCGATATCGTTGTGAACGCCTGCGGCTACCGTGTGAACGAGGTTGGCAGTA
TGATGGGCGTGCATCACCCTGTCGCCTCGATGGAGCATCAGTATTTCGTTACCGAAGACATCCCCGCGATAGTCGAGGCG
GGGCACCGAATGCCTCTGCTGCGCTGCCCGATCTCTGACTATTATGCGCGCCAGGAAAAGAACGGCCTCCTGGTGGGTTT
TTACGAACAGGATTGCAAGACATGGGGCATGGACGGGATCAGCCCGAGCTTTGCCAATGACCTGTGCCCGGATGATCTTG
ACCGTGTGATGGACGTGCTGGAGGGAGCGTTTGAACGCATGCCTGCCTTGTCTGAAGTGGGCATCAAGCGGGTGGTGAAC
GGCCCGATCACCTATACCATCGACGGCGCGCCACTTGTCGGTCCGATCCCCGGCAAACGCAATGCCTACTGTATCATCGG
CTTGCGCGCAGGTGTCGGCGAAGGCGGTGGCCATGGCTGGCTGCTCGCGCAACAGATCGTGCACGGTGAGGCGGAGTATG
ACACTTGGGTCCTTGATCCGCGTCGCTTCACCGGTCACGCAAATGTCGAACTGACAGCACTCAAGGCGATCGAGGACTAT
CAGAACGAGTTCCGCTTCCATTTCCCGCATGAACATCGCCCGGCTGGCCGCAATGCCAAGACGACCCCGCTCACGCCTGT
CATGGCCGCTGAGGGTGCCGCCTTCACCGTCGTCAATGGCTGGGAGCGGGTCGATTACATCAAGCCCGCACCGGATTTCC
ACCCGTCGCTGAGCTTCAATTTTGACGAAACCTTTGATGTCATTGGCGACGAAGTCCGCAATGTGCAGCAGAATGTCGGC
CTCTGTGAGGTCAATGGCTTCAACCGGTTTGAGATCACCGGCACGGATCGACACAGCTTCCTGGATCGGATGTTCTGCGG
TGCGGTGCGCAGAAAGGACGGCCGCGTCGGCCTAGGCTACATGCTGAACCATCACGGGAAGATCAAGGCCGAGGCGACCA
TCGCCAATATCCCCGCTTCTGACAGGGGACCTGCGCGGCTTTGGTATGGCTCGGCTGCGGCGTCCGAGTATCATGATATG
GACTGGCTGACCCGGCATGTGCAGCCGGACGAAGACGTGCAGATCCGCAGTCTGACCAATGATCAGACGGTGCTCGTACT
GGCCGGTCCCAAGGCGCGTGACGTGCTGTCAGCCTGTTCGCGCGGCGATTGGTCCAAAGCGGCCTTCCCTTGGTTGTCGG
TGCGCGAAGCTTTTGTCGGCTTCTCTCCTGTCACCGTTCTGGGCGTCAGCTTTTCCGGCGAGCTTGCCTATGAAATCCAC
GTACCGAACGCGTCGCTTTATGCCGTCTATCTTGCGTTGCGGGAGGCTGGACAGGCACATTGTCTCACGCTCTTTGGCGC
GCGCGCGGTTGACTCGATGCGAATGGAAAAAGGCTTCCTGCACTGGAAAGCCGAACTGCTTACCGAATTTGATCCGTTTG
AAACGGGGCTGGACAGGTTCGTGAAACCCGAAAAAAGACCGTTCATCGGTCAGCAGGCCTTGCAAAAGCGCATGGCAAAC
GGGCCGATCCGCAAACTTGTGACCCTCAAGATCGACTGCACCACGGCACCGGCGCACGGTGGCGCTTCATTGATGCAGGA
CGGTGCGGTGGTGGGTACGATCACATCGGGCGCGTGGGGATACCGCGTCGGTTTGAACCTCGCCTATGCCTTTGTCATTC
CGGAAATGGCCGAAATTGGCCGCGCCATGCAATTGGACCTCTGCGGCGAACTGGTGTCAGCAGAGGTCATTGCGCCGTCA
CCCTATGATCCTGAACACGCACGGATGCAGGCGTGA

Upstream 100 bases:

>100_bases
AATGTAGTACTTTTCCAGACATATAAGAATGAAAACCGGAATCCTGCGCGGCGAGGAGGAGCACTTGCTTGCCAGCGCAT
TGTTTCCTTGGGGGGCGGAC

Downstream 100 bases:

>100_bases
ACCACGCCGCGGCCCTCAAGGCGCGCATGCCCTTGCCGCAGCGGTGAAACGCTGACGCGCAACGTTTTCCATCTCACAAA
AAGTGCATCGACGTCGTTTT

Product: dimethylglycine dehydrogenase, putative

Products: NA

Alternate protein names: Sarcosine oxidase subunit [H]

Number of amino acids: Translated: 811; Mature: 811

Protein sequence:

>811_residues
MKSRTKVAVIGGGIAGCSTLYHLTEEGWSDVVLIERDELTSGTTWHSAAQVTNFGMNQTMVGLKTHSIRLYKKLRDDPDY
PVGYHHGDGGIRLANTPEQMQAYRHFASMARGMGTDFEVIDARECARRHPLISTDNLLGGLWDGEDGDIDPAQLCQALAF
HARKAGAEVYRHTNVTALTQHADDTWTVETDKGRIDADIVVNACGYRVNEVGSMMGVHHPVASMEHQYFVTEDIPAIVEA
GHRMPLLRCPISDYYARQEKNGLLVGFYEQDCKTWGMDGISPSFANDLCPDDLDRVMDVLEGAFERMPALSEVGIKRVVN
GPITYTIDGAPLVGPIPGKRNAYCIIGLRAGVGEGGGHGWLLAQQIVHGEAEYDTWVLDPRRFTGHANVELTALKAIEDY
QNEFRFHFPHEHRPAGRNAKTTPLTPVMAAEGAAFTVVNGWERVDYIKPAPDFHPSLSFNFDETFDVIGDEVRNVQQNVG
LCEVNGFNRFEITGTDRHSFLDRMFCGAVRRKDGRVGLGYMLNHHGKIKAEATIANIPASDRGPARLWYGSAAASEYHDM
DWLTRHVQPDEDVQIRSLTNDQTVLVLAGPKARDVLSACSRGDWSKAAFPWLSVREAFVGFSPVTVLGVSFSGELAYEIH
VPNASLYAVYLALREAGQAHCLTLFGARAVDSMRMEKGFLHWKAELLTEFDPFETGLDRFVKPEKRPFIGQQALQKRMAN
GPIRKLVTLKIDCTTAPAHGGASLMQDGAVVGTITSGAWGYRVGLNLAYAFVIPEMAEIGRAMQLDLCGELVSAEVIAPS
PYDPEHARMQA

Sequences:

>Translated_811_residues
MKSRTKVAVIGGGIAGCSTLYHLTEEGWSDVVLIERDELTSGTTWHSAAQVTNFGMNQTMVGLKTHSIRLYKKLRDDPDY
PVGYHHGDGGIRLANTPEQMQAYRHFASMARGMGTDFEVIDARECARRHPLISTDNLLGGLWDGEDGDIDPAQLCQALAF
HARKAGAEVYRHTNVTALTQHADDTWTVETDKGRIDADIVVNACGYRVNEVGSMMGVHHPVASMEHQYFVTEDIPAIVEA
GHRMPLLRCPISDYYARQEKNGLLVGFYEQDCKTWGMDGISPSFANDLCPDDLDRVMDVLEGAFERMPALSEVGIKRVVN
GPITYTIDGAPLVGPIPGKRNAYCIIGLRAGVGEGGGHGWLLAQQIVHGEAEYDTWVLDPRRFTGHANVELTALKAIEDY
QNEFRFHFPHEHRPAGRNAKTTPLTPVMAAEGAAFTVVNGWERVDYIKPAPDFHPSLSFNFDETFDVIGDEVRNVQQNVG
LCEVNGFNRFEITGTDRHSFLDRMFCGAVRRKDGRVGLGYMLNHHGKIKAEATIANIPASDRGPARLWYGSAAASEYHDM
DWLTRHVQPDEDVQIRSLTNDQTVLVLAGPKARDVLSACSRGDWSKAAFPWLSVREAFVGFSPVTVLGVSFSGELAYEIH
VPNASLYAVYLALREAGQAHCLTLFGARAVDSMRMEKGFLHWKAELLTEFDPFETGLDRFVKPEKRPFIGQQALQKRMAN
GPIRKLVTLKIDCTTAPAHGGASLMQDGAVVGTITSGAWGYRVGLNLAYAFVIPEMAEIGRAMQLDLCGELVSAEVIAPS
PYDPEHARMQA
>Mature_811_residues
MKSRTKVAVIGGGIAGCSTLYHLTEEGWSDVVLIERDELTSGTTWHSAAQVTNFGMNQTMVGLKTHSIRLYKKLRDDPDY
PVGYHHGDGGIRLANTPEQMQAYRHFASMARGMGTDFEVIDARECARRHPLISTDNLLGGLWDGEDGDIDPAQLCQALAF
HARKAGAEVYRHTNVTALTQHADDTWTVETDKGRIDADIVVNACGYRVNEVGSMMGVHHPVASMEHQYFVTEDIPAIVEA
GHRMPLLRCPISDYYARQEKNGLLVGFYEQDCKTWGMDGISPSFANDLCPDDLDRVMDVLEGAFERMPALSEVGIKRVVN
GPITYTIDGAPLVGPIPGKRNAYCIIGLRAGVGEGGGHGWLLAQQIVHGEAEYDTWVLDPRRFTGHANVELTALKAIEDY
QNEFRFHFPHEHRPAGRNAKTTPLTPVMAAEGAAFTVVNGWERVDYIKPAPDFHPSLSFNFDETFDVIGDEVRNVQQNVG
LCEVNGFNRFEITGTDRHSFLDRMFCGAVRRKDGRVGLGYMLNHHGKIKAEATIANIPASDRGPARLWYGSAAASEYHDM
DWLTRHVQPDEDVQIRSLTNDQTVLVLAGPKARDVLSACSRGDWSKAAFPWLSVREAFVGFSPVTVLGVSFSGELAYEIH
VPNASLYAVYLALREAGQAHCLTLFGARAVDSMRMEKGFLHWKAELLTEFDPFETGLDRFVKPEKRPFIGQQALQKRMAN
GPIRKLVTLKIDCTTAPAHGGASLMQDGAVVGTITSGAWGYRVGLNLAYAFVIPEMAEIGRAMQLDLCGELVSAEVIAPS
PYDPEHARMQA

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=820, Percent_Identity=35.2439024390244, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI197927446, Length=867, Percent_Identity=31.1418685121107, Blast_Score=362, Evalue=1e-99,
Organism=Homo sapiens, GI21361378, Length=867, Percent_Identity=31.1418685121107, Blast_Score=362, Evalue=1e-99,
Organism=Homo sapiens, GI194306651, Length=798, Percent_Identity=27.9448621553885, Blast_Score=279, Evalue=8e-75,
Organism=Homo sapiens, GI257796258, Length=377, Percent_Identity=24.6684350132626, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI44662838, Length=396, Percent_Identity=24.2424242424242, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789272, Length=273, Percent_Identity=25.2747252747253, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994045, Length=803, Percent_Identity=27.3972602739726, Blast_Score=240, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI71994052, Length=810, Percent_Identity=27.1604938271605, Blast_Score=237, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI32563613, Length=845, Percent_Identity=24.3786982248521, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17560118, Length=350, Percent_Identity=25.1428571428571, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20130091, Length=856, Percent_Identity=27.5700934579439, Blast_Score=290, Evalue=3e-78,
Organism=Drosophila melanogaster, GI28571104, Length=776, Percent_Identity=27.0618556701031, Blast_Score=277, Evalue=2e-74,
Organism=Drosophila melanogaster, GI20129441, Length=263, Percent_Identity=27.7566539923954, Blast_Score=76, Evalue=9e-14,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006277 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C; PF07992 Pyr_redox_2 [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 89432; Mature: 89432

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRTKVAVIGGGIAGCSTLYHLTEEGWSDVVLIERDELTSGTTWHSAAQVTNFGMNQTM
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEE
VGLKTHSIRLYKKLRDDPDYPVGYHHGDGGIRLANTPEQMQAYRHFASMARGMGTDFEVI
EEEEHHHHHHHHHHCCCCCCCCCEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEE
DARECARRHPLISTDNLLGGLWDGEDGDIDPAQLCQALAFHARKAGAEVYRHTNVTALTQ
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HADDTWTVETDKGRIDADIVVNACGYRVNEVGSMMGVHHPVASMEHQYFVTEDIPAIVEA
CCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHCCCCEEEECCCHHHHHC
GHRMPLLRCPISDYYARQEKNGLLVGFYEQDCKTWGMDGISPSFANDLCPDDLDRVMDVL
CCCCCEEECCCHHHHHHHCCCCEEEEEEHHCCHHCCCCCCCCHHHCCCCHHHHHHHHHHH
EGAFERMPALSEVGIKRVVNGPITYTIDGAPLVGPIPGKRNAYCIIGLRAGVGEGGGHGW
HHHHHHCCCHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCEEEEEEEECCCCCCCCCHH
LLAQQIVHGEAEYDTWVLDPRRFTGHANVELTALKAIEDYQNEFRFHFPHEHRPAGRNAK
HHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEHHHHHHHHHCCEEECCCCCCCCCCCCC
TTPLTPVMAAEGAAFTVVNGWERVDYIKPAPDFHPSLSFNFDETFDVIGDEVRNVQQNVG
CCCCCCEEECCCCEEEEECCCHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHCC
LCEVNGFNRFEITGTDRHSFLDRMFCGAVRRKDGRVGLGYMLNHHGKIKAEATIANIPAS
EEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCEECCCCCEEEEEEEEECCCC
DRGPARLWYGSAAASEYHDMDWLTRHVQPDEDVQIRSLTNDQTVLVLAGPKARDVLSACS
CCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHC
RGDWSKAAFPWLSVREAFVGFSPVTVLGVSFSGELAYEIHVPNASLYAVYLALREAGQAH
CCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCE
CLTLFGARAVDSMRMEKGFLHWKAELLTEFDPFETGLDRFVKPEKRPFIGQQALQKRMAN
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCC
GPIRKLVTLKIDCTTAPAHGGASLMQDGAVVGTITSGAWGYRVGLNLAYAFVIPEMAEIG
CCCEEEEEEEEEEECCCCCCCHHHHHCCCEEEEEECCCCEEEECCEEEEEHHHHHHHHHC
RAMQLDLCGELVSAEVIAPSPYDPEHARMQA
CCEEHHHHHHHHHCEEECCCCCCCCHHCCCC
>Mature Secondary Structure
MKSRTKVAVIGGGIAGCSTLYHLTEEGWSDVVLIERDELTSGTTWHSAAQVTNFGMNQTM
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEE
VGLKTHSIRLYKKLRDDPDYPVGYHHGDGGIRLANTPEQMQAYRHFASMARGMGTDFEVI
EEEEHHHHHHHHHHCCCCCCCCCEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEE
DARECARRHPLISTDNLLGGLWDGEDGDIDPAQLCQALAFHARKAGAEVYRHTNVTALTQ
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HADDTWTVETDKGRIDADIVVNACGYRVNEVGSMMGVHHPVASMEHQYFVTEDIPAIVEA
CCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHCCCCEEEECCCHHHHHC
GHRMPLLRCPISDYYARQEKNGLLVGFYEQDCKTWGMDGISPSFANDLCPDDLDRVMDVL
CCCCCEEECCCHHHHHHHCCCCEEEEEEHHCCHHCCCCCCCCHHHCCCCHHHHHHHHHHH
EGAFERMPALSEVGIKRVVNGPITYTIDGAPLVGPIPGKRNAYCIIGLRAGVGEGGGHGW
HHHHHHCCCHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCEEEEEEEECCCCCCCCCHH
LLAQQIVHGEAEYDTWVLDPRRFTGHANVELTALKAIEDYQNEFRFHFPHEHRPAGRNAK
HHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEHHHHHHHHHCCEEECCCCCCCCCCCCC
TTPLTPVMAAEGAAFTVVNGWERVDYIKPAPDFHPSLSFNFDETFDVIGDEVRNVQQNVG
CCCCCCEEECCCCEEEEECCCHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHCC
LCEVNGFNRFEITGTDRHSFLDRMFCGAVRRKDGRVGLGYMLNHHGKIKAEATIANIPAS
EEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCEECCCCCEEEEEEEEECCCC
DRGPARLWYGSAAASEYHDMDWLTRHVQPDEDVQIRSLTNDQTVLVLAGPKARDVLSACS
CCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHC
RGDWSKAAFPWLSVREAFVGFSPVTVLGVSFSGELAYEIHVPNASLYAVYLALREAGQAH
CCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCCE
CLTLFGARAVDSMRMEKGFLHWKAELLTEFDPFETGLDRFVKPEKRPFIGQQALQKRMAN
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCC
GPIRKLVTLKIDCTTAPAHGGASLMQDGAVVGTITSGAWGYRVGLNLAYAFVIPEMAEIG
CCCEEEEEEEEEEECCCCCCCHHHHHCCCEEEEEECCCCEEEECCEEEEEHHHHHHHHHC
RAMQLDLCGELVSAEVIAPSPYDPEHARMQA
CCEEHHHHHHHHHCEEECCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]