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The map label for this gene is gpo [H]

Identifier: 110677978

GI number: 110677978

Start: 580959

End: 581507

Strand: Direct

Name: gpo [H]

Synonym: RD1_0599

Alternate gene names: 110677978

Gene position: 580959-581507 (Clockwise)

Preceding gene: 110677971

Following gene: 110677979

Centisome position: 14.06

GC content: 56.28

Gene sequence:

>549_bases
ATGAAAGCTCTGAAATCAACAGTGGCGGCACTTGTCACAGCCGCATTTGTCGCAGGTCCGGTCTGTGCGGGGGCACGCGA
TCACCAGTTTGCGTCCATCGACGGCGGGTTTGTGGACATGGCCGATTGGGCAGGGCAGCCCGTGCTGGTCGTCAACACTG
CCTCGCAATGTGGTTTTACGGGCCAATATGCGGGGCTGCAGGAACTCTATGACACCTACCGCGCGGCCGGTCTGGTGGTT
TTTGCGGTTCCATCGGATGATTTCAATCAGGAACTTGGCAGCGCGGAAGAGGTCAAGGAATTCTGCGAAATGAACTTTGG
ACTCGATCTGCCGATGGCGGATATCACCCGCATCCGGGGCAAGAACGCGCATCCGTTCTATCAGGATGTGCGTGCGGAAA
CCGGGTTCGTGCCGCGCTGGAATTTCAACAAGGTATTGATCGGTCCGGATGGCGAAATCGTTGACACCTGGGGTTCGCAG
ACAAAACCAATGTCGCGTGAGATTACCGACGCGGTTGAAACACTATTGGATCAAGCAAGTCAGGGCTGA

Upstream 100 bases:

>100_bases
CGCAAAACCCATAAAGAAAAGGGGCAAACCGACGCAACAGGTGGGATGTGTCTTTTTGACGGGGCGGACTATATTCCACC
TCACAGTGGAGGAGACGCGA

Downstream 100 bases:

>100_bases
GTTTTGACGCAGGAGAAAGAAGACAAACGGCTGGACCTGCAAGCGGCCTATTCCGTCCGGACCCCGGCGGAGAATGAGGC
GCTTTATGCGGCCTGGGCCA

Product: glutathione peroxidase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKALKSTVAALVTAAFVAGPVCAGARDHQFASIDGGFVDMADWAGQPVLVVNTASQCGFTGQYAGLQELYDTYRAAGLVV
FAVPSDDFNQELGSAEEVKEFCEMNFGLDLPMADITRIRGKNAHPFYQDVRAETGFVPRWNFNKVLIGPDGEIVDTWGSQ
TKPMSREITDAVETLLDQASQG

Sequences:

>Translated_182_residues
MKALKSTVAALVTAAFVAGPVCAGARDHQFASIDGGFVDMADWAGQPVLVVNTASQCGFTGQYAGLQELYDTYRAAGLVV
FAVPSDDFNQELGSAEEVKEFCEMNFGLDLPMADITRIRGKNAHPFYQDVRAETGFVPRWNFNKVLIGPDGEIVDTWGSQ
TKPMSREITDAVETLLDQASQG
>Mature_182_residues
MKALKSTVAALVTAAFVAGPVCAGARDHQFASIDGGFVDMADWAGQPVLVVNTASQCGFTGQYAGLQELYDTYRAAGLVV
FAVPSDDFNQELGSAEEVKEFCEMNFGLDLPMADITRIRGKNAHPFYQDVRAETGFVPRWNFNKVLIGPDGEIVDTWGSQ
TKPMSREITDAVETLLDQASQG

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=133, Percent_Identity=35.3383458646617, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI192455698, Length=129, Percent_Identity=31.7829457364341, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI75709200, Length=179, Percent_Identity=30.7262569832402, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI90903240, Length=147, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI90903238, Length=156, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788003, Length=169, Percent_Identity=30.1775147928994, Blast_Score=91, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17506887, Length=158, Percent_Identity=31.0126582278481, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17535473, Length=145, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993584, Length=156, Percent_Identity=28.8461538461538, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319721, Length=141, Percent_Identity=37.5886524822695, Blast_Score=105, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322228, Length=142, Percent_Identity=35.2112676056338, Blast_Score=102, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322826, Length=162, Percent_Identity=32.0987654320988, Blast_Score=98, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24656772, Length=187, Percent_Identity=31.0160427807487, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24656777, Length=153, Percent_Identity=32.0261437908497, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24656767, Length=153, Percent_Identity=32.0261437908497, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 19660; Mature: 19660

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALKSTVAALVTAAFVAGPVCAGARDHQFASIDGGFVDMADWAGQPVLVVNTASQCGFT
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEHHHHCCCCEEEEECCHHCCCC
GQYAGLQELYDTYRAAGLVVFAVPSDDFNQELGSAEEVKEFCEMNFGLDLPMADITRIRG
CCHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHCC
KNAHPFYQDVRAETGFVPRWNFNKVLIGPDGEIVDTWGSQTKPMSREITDAVETLLDQAS
CCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHC
QG
CC
>Mature Secondary Structure
MKALKSTVAALVTAAFVAGPVCAGARDHQFASIDGGFVDMADWAGQPVLVVNTASQCGFT
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEHHHHCCCCEEEEECCHHCCCC
GQYAGLQELYDTYRAAGLVVFAVPSDDFNQELGSAEEVKEFCEMNFGLDLPMADITRIRG
CCHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHCC
KNAHPFYQDVRAETGFVPRWNFNKVLIGPDGEIVDTWGSQTKPMSREITDAVETLLDQAS
CCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHC
QG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]