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The map label for this gene is yggV [C]

Identifier: 110677821

GI number: 110677821

Start: 417902

End: 418513

Strand: Direct

Name: yggV [C]

Synonym: RD1_0427

Alternate gene names: 110677821

Gene position: 417902-418513 (Clockwise)

Preceding gene: 110677820

Following gene: 110677822

Centisome position: 10.11

GC content: 60.95

Gene sequence:

>612_bases
ATGACACGCAAGTTCGACGGCAAACGTATCCTGATTGCGACCCATAACGCGGGCAAGCTGGAAGAAATGCAGCAGCTTTT
CGCGCCCTACGGTGTGGATGTGGTCGGCGCCGCAGAGATGGGTCTGGCCGAACCTGAAGAGACCGAAAGCACCTTCATCG
GCAACGCACGCATCAAGGCGCGCGCTGCTGTTGAGGCGACAGGGCTGCCCGCCCTGGCGGACGATTCCGGCATCGAGGTG
GAAGCGCTGAACAACGCCCCCGGTGTCTATACCGCTGATTGGGCGGAGACCCCGAACGGGCGCGATTTCGTCATGGCCAT
GACCAAGACCCATACCAAGCTGGAAGAGATCAACGCCCCCCACCCGCGCCGCGCCCGGTTCAGGGCGACGCTGGTGCTCG
CATGGCCTGACGGTCATGACGAAGTGTTCGATGGGCGCGTCAACGGCACCCTTGTCTGGCCGATCCGGGGTAAAACGGGT
CATGGCTATGATCCGATGTTCCAACCTGACGGTCATGACATGACCTTTGCCGAAATGGATCCGGCGGAAAAGAACCGGAT
CAGCCATCGCGCGGATGCGTTTCAAAAGCTGATCGCGGGTTGCTTTGGCTGA

Upstream 100 bases:

>100_bases
CCGAAGGCGCGACGTTTTCACGCGATCAGATGAACCAGTTGATGGATCTGGCCGAAAAGGGCGTGGGCGAATTGGTCGCC
GCGCAAAAAGCGGCCACCGC

Downstream 100 bases:

>100_bases
AGACTGGGAACACGGCGGCTTTGGCCTCTATATCCACTGGCCCTATTGCGAGGCCAAATGTCCGTATTGTGATTTCAACA
GCCATGTGGTGCGCCGCATT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTRKFDGKRILIATHNAGKLEEMQQLFAPYGVDVVGAAEMGLAEPEETESTFIGNARIKARAAVEATGLPALADDSGIEV
EALNNAPGVYTADWAETPNGRDFVMAMTKTHTKLEEINAPHPRRARFRATLVLAWPDGHDEVFDGRVNGTLVWPIRGKTG
HGYDPMFQPDGHDMTFAEMDPAEKNRISHRADAFQKLIAGCFG

Sequences:

>Translated_203_residues
MTRKFDGKRILIATHNAGKLEEMQQLFAPYGVDVVGAAEMGLAEPEETESTFIGNARIKARAAVEATGLPALADDSGIEV
EALNNAPGVYTADWAETPNGRDFVMAMTKTHTKLEEINAPHPRRARFRATLVLAWPDGHDEVFDGRVNGTLVWPIRGKTG
HGYDPMFQPDGHDMTFAEMDPAEKNRISHRADAFQKLIAGCFG
>Mature_202_residues
TRKFDGKRILIATHNAGKLEEMQQLFAPYGVDVVGAAEMGLAEPEETESTFIGNARIKARAAVEATGLPALADDSGIEVE
ALNNAPGVYTADWAETPNGRDFVMAMTKTHTKLEEINAPHPRRARFRATLVLAWPDGHDEVFDGRVNGTLVWPIRGKTGH
GYDPMFQPDGHDMTFAEMDPAEKNRISHRADAFQKLIAGCFG

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=205, Percent_Identity=32.1951219512195, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI31657144, Length=143, Percent_Identity=34.2657342657343, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=37.7551020408163, Blast_Score=113, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17556833, Length=195, Percent_Identity=33.8461538461538, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322529, Length=195, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920712, Length=196, Percent_Identity=29.0816326530612, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22249; Mature: 22118

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKFDGKRILIATHNAGKLEEMQQLFAPYGVDVVGAAEMGLAEPEETESTFIGNARIKA
CCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEECHHHCCCCCCCCCCCEEECCCEEEE
RAAVEATGLPALADDSGIEVEALNNAPGVYTADWAETPNGRDFVMAMTKTHTKLEEINAP
EEEEEECCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEEEHHHHHHHHCCCC
HPRRARFRATLVLAWPDGHDEVFDGRVNGTLVWPIRGKTGHGYDPMFQPDGHDMTFAEMD
CCCCEEEEEEEEEECCCCCCCEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCC
PAEKNRISHRADAFQKLIAGCFG
CHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRKFDGKRILIATHNAGKLEEMQQLFAPYGVDVVGAAEMGLAEPEETESTFIGNARIKA
CCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEECHHHCCCCCCCCCCCEEECCCEEEE
RAAVEATGLPALADDSGIEVEALNNAPGVYTADWAETPNGRDFVMAMTKTHTKLEEINAP
EEEEEECCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEEEHHHHHHHHCCCC
HPRRARFRATLVLAWPDGHDEVFDGRVNGTLVWPIRGKTGHGYDPMFQPDGHDMTFAEMD
CCCCEEEEEEEEEECCCCCCCEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCC
PAEKNRISHRADAFQKLIAGCFG
CHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA