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The map label for this gene is prsA [H]

Identifier: 110677781

GI number: 110677781

Start: 375943

End: 376800

Strand: Direct

Name: prsA [H]

Synonym: RD1_0383

Alternate gene names: 110677781

Gene position: 375943-376800 (Clockwise)

Preceding gene: 110677778

Following gene: 110677782

Centisome position: 9.1

GC content: 56.18

Gene sequence:

>858_bases
ATGCAAAAACATCTCAGAATTCTGGCTTTTTCCGCGTTGACGGCAGCGATTGCTGCCCCTGTGGTTGCACAGGATGACAC
CGCGCTGACGGCAGACACGGTCATCGCGACAGTGAATGGCGAGGACATCAAGCTGGGTCACATGATCGCAGCGCGCGCCA
CGTTGGGTGAACGCTATAATCAGATGCCCGCTGAGCAGCTGTGGAATGGAATTGTTGAACAACTGATTCAGCAGACCGCA
TTGGCACAGGGAATTGAAAGCCTGTCCGCCGGGGAGGCGATGGCGCTGGAAAATCAGGAACGCTCCCTGAAGGCCGCCAA
GGCGATCGAAATAGGGCTGGAACAGGCCGTCACCGAAGAGGACATACAAGCGGCCTATGACGCAGAATTTGGCAACCTGG
ACCCCGAAGAAGAGTTCAACGCCTCCCATATTCTGGTCGCGACCGAAGAAGAAGCAATCGCAGTGAAAGAAGCGATTGAT
GGCGGTGCGAATTTCGCGGCAACCGCGCGGGAGAAATCAACCGGACCCTCCGGCCCGAATGGCGGCGAGTTGGGATGGTT
CAGCACGGGCATGATGGTTCCGAGTTTCGAAGCCGCAACCATCGCACTGGAGGTCGGAGAGGTCTCTGATCCTGTTGAAA
CGCAATTCGGCTGGCATGTGATCACCCTTAACGACACGCGGCAAAAGAACATTCCGACGCTCGAAGAAGCACGGGAAGGC
ATAGAGGCTCGTCTCGCGCAGGATGCAGCACTTGGTATCATCCAAAACGCAGCTGCCGGAGCAGCGATTGAGGTGACGCC
GTTTGAAAACGCAGATGAGCGGTTCGATCTGATCAACCGGTTCGACCTTTTGGAATAA

Upstream 100 bases:

>100_bases
TTGATCGCTACACTCTTGCAGCGCCACACGCGGGATGTAAGGGTCACGCCAAACCGTGTCAATGTCGCGCCCCGTCGCGA
CCCCCTCATAGGACGATTAC

Downstream 100 bases:

>100_bases
CGAAACATGGCTAAAATTACCGTTGTATCGCCACTGGCACCCAAGAGGTTTCCAGAGATGCCGGTCATTGACGGCGTTTC
GTTTTCGACCGTTGCCGCCG

Product: peptidyl-prolyl cis-trans isomerase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MQKHLRILAFSALTAAIAAPVVAQDDTALTADTVIATVNGEDIKLGHMIAARATLGERYNQMPAEQLWNGIVEQLIQQTA
LAQGIESLSAGEAMALENQERSLKAAKAIEIGLEQAVTEEDIQAAYDAEFGNLDPEEEFNASHILVATEEEAIAVKEAID
GGANFAATAREKSTGPSGPNGGELGWFSTGMMVPSFEAATIALEVGEVSDPVETQFGWHVITLNDTRQKNIPTLEEAREG
IEARLAQDAALGIIQNAAAGAAIEVTPFENADERFDLINRFDLLE

Sequences:

>Translated_285_residues
MQKHLRILAFSALTAAIAAPVVAQDDTALTADTVIATVNGEDIKLGHMIAARATLGERYNQMPAEQLWNGIVEQLIQQTA
LAQGIESLSAGEAMALENQERSLKAAKAIEIGLEQAVTEEDIQAAYDAEFGNLDPEEEFNASHILVATEEEAIAVKEAID
GGANFAATAREKSTGPSGPNGGELGWFSTGMMVPSFEAATIALEVGEVSDPVETQFGWHVITLNDTRQKNIPTLEEAREG
IEARLAQDAALGIIQNAAAGAAIEVTPFENADERFDLINRFDLLE
>Mature_285_residues
MQKHLRILAFSALTAAIAAPVVAQDDTALTADTVIATVNGEDIKLGHMIAARATLGERYNQMPAEQLWNGIVEQLIQQTA
LAQGIESLSAGEAMALENQERSLKAAKAIEIGLEQAVTEEDIQAAYDAEFGNLDPEEEFNASHILVATEEEAIAVKEAID
GGANFAATAREKSTGPSGPNGGELGWFSTGMMVPSFEAATIALEVGEVSDPVETQFGWHVITLNDTRQKNIPTLEEAREG
IEARLAQDAALGIIQNAAAGAAIEVTPFENADERFDLINRFDLLE

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=83, Percent_Identity=43.3734939759036, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786645, Length=140, Percent_Identity=30.7142857142857, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786238, Length=101, Percent_Identity=40.5940594059406, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 30415; Mature: 30415

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKHLRILAFSALTAAIAAPVVAQDDTALTADTVIATVNGEDIKLGHMIAARATLGERYN
CCCHHHHHHHHHHHHHHHCCCEECCCCCEEECEEEEEECCCCEEHHHHHHHHHHHHHHHH
QMPAEQLWNGIVEQLIQQTALAQGIESLSAGEAMALENQERSLKAAKAIEIGLEQAVTEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
DIQAAYDAEFGNLDPEEEFNASHILVATEEEAIAVKEAIDGGANFAATAREKSTGPSGPN
HHHHHHCCCCCCCCCHHHCCCCEEEEEECCHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
GGELGWFSTGMMVPSFEAATIALEVGEVSDPVETQFGWHVITLNDTRQKNIPTLEEAREG
CCCCCEEECCCCCCCCCCEEEEEEECCCCCCCHHCCCEEEEEECCCCCCCCCCHHHHHHH
IEARLAQDAALGIIQNAAAGAAIEVTPFENADERFDLINRFDLLE
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKHLRILAFSALTAAIAAPVVAQDDTALTADTVIATVNGEDIKLGHMIAARATLGERYN
CCCHHHHHHHHHHHHHHHCCCEECCCCCEEECEEEEEECCCCEEHHHHHHHHHHHHHHHH
QMPAEQLWNGIVEQLIQQTALAQGIESLSAGEAMALENQERSLKAAKAIEIGLEQAVTEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
DIQAAYDAEFGNLDPEEEFNASHILVATEEEAIAVKEAIDGGANFAATAREKSTGPSGPN
HHHHHHCCCCCCCCCHHHCCCCEEEEEECCHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
GGELGWFSTGMMVPSFEAATIALEVGEVSDPVETQFGWHVITLNDTRQKNIPTLEEAREG
CCCCCEEECCCCCCCCCCEEEEEEECCCCCCCHHCCCEEEEEECCCCCCCCCCHHHHHHH
IEARLAQDAALGIIQNAAAGAAIEVTPFENADERFDLINRFDLLE
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA