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The map label for this gene is ycgM [C]

Identifier: 110635873

GI number: 110635873

Start: 3819936

End: 3820781

Strand: Reverse

Name: ycgM [C]

Synonym: Meso_3545

Alternate gene names: 110635873

Gene position: 3820781-3819936 (Counterclockwise)

Preceding gene: 110635874

Following gene: 110635871

Centisome position: 86.59

GC content: 57.45

Gene sequence:

>846_bases
ATGAAGTTTCTTCGCTATGGCGAAACCGGACAGGAGAAGCCGGGTCTTCTCGATGCCGACGGCAATATTCGTGACCTGTC
CGCGCATATCAGCGATCTGTCGGGTGGAGCTCTGAATCCCGAAGCGCTGGCCAAGCTTGGCTCACTCGATGTCAATTCAT
TACCAAAGGTCGAAGGCAACCCGCGTCTGGGCCCGTGTGTTGCGGGTACCGGCAAGTTCATCTGCATTGGTCTCAACTAT
TCCGACCACGCCGCCGAAACCGGCGCCGCTGTTCCGTCCGAGCCGATCATCTTCATGAAGGCCACTTCGGCGATCGTCGG
CCCGAACGACGATCTCATCATCCCGCGCGGTTCTGAAAAGACCGACTGGGAGGTCGAGCTCGGCATTGTCATCGGCAAGA
CCGCAAAATATGTCAGCGAAGATAACGCGCTCGACTATGTGGCCGGCTATTGCACCATTCACGACGTTTCCGAACGTGCC
TTCCAGATCGAACGTCAGGGCCAATGGACCAAGGGCAAGTCCTGCGACACGTTCGGCCCGACCGGTCCATGGCTCGTCAC
CAAGGACGAGATTGCAGACCCGGAAAATCTCGGCATGTGGCTGACGGTCAATGGCGAAACCATGCAGAACGGTTCGTCGA
AAACCATGATCTATGGCATACGCCATCTCGTTTCTTATCTGTCGCAGTTTATGTCGCTGCAGCCTGGTGACATCATCTCC
ACAGGCACGCCCCCCGGCGTCGGCATGGGTATGAAGCCCCCGCGCTATCTCAAGCCTGGCGACGTTGTCGAACTTGGCAT
CGAAGGGCTTGGCACTCAGAAACAGAACGTGCGCGCCGATATCTGA

Upstream 100 bases:

>100_bases
TCGCTGGCGCCACTTATACGACCGGCCAAGCGTACAATATCGACGGCGGCTGGACGATTTAAATCCTCAGCCGCTTCACC
AATCTCCCAGGAGTAAACAC

Downstream 100 bases:

>100_bases
TCACGGGTGAAGTCGCACACCTCACCCGTAACACTTCCGGATTGCTGATTGACGGCGACGGCAATACCGAGCGTTGTTAC
GCTATTCTGACGAGGCACCG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKFLRYGETGQEKPGLLDADGNIRDLSAHISDLSGGALNPEALAKLGSLDVNSLPKVEGNPRLGPCVAGTGKFICIGLNY
SDHAAETGAAVPSEPIIFMKATSAIVGPNDDLIIPRGSEKTDWEVELGIVIGKTAKYVSEDNALDYVAGYCTIHDVSERA
FQIERQGQWTKGKSCDTFGPTGPWLVTKDEIADPENLGMWLTVNGETMQNGSSKTMIYGIRHLVSYLSQFMSLQPGDIIS
TGTPPGVGMGMKPPRYLKPGDVVELGIEGLGTQKQNVRADI

Sequences:

>Translated_281_residues
MKFLRYGETGQEKPGLLDADGNIRDLSAHISDLSGGALNPEALAKLGSLDVNSLPKVEGNPRLGPCVAGTGKFICIGLNY
SDHAAETGAAVPSEPIIFMKATSAIVGPNDDLIIPRGSEKTDWEVELGIVIGKTAKYVSEDNALDYVAGYCTIHDVSERA
FQIERQGQWTKGKSCDTFGPTGPWLVTKDEIADPENLGMWLTVNGETMQNGSSKTMIYGIRHLVSYLSQFMSLQPGDIIS
TGTPPGVGMGMKPPRYLKPGDVVELGIEGLGTQKQNVRADI
>Mature_281_residues
MKFLRYGETGQEKPGLLDADGNIRDLSAHISDLSGGALNPEALAKLGSLDVNSLPKVEGNPRLGPCVAGTGKFICIGLNY
SDHAAETGAAVPSEPIIFMKATSAIVGPNDDLIIPRGSEKTDWEVELGIVIGKTAKYVSEDNALDYVAGYCTIHDVSERA
FQIERQGQWTKGKSCDTFGPTGPWLVTKDEIADPENLGMWLTVNGETMQNGSSKTMIYGIRHLVSYLSQFMSLQPGDIIS
TGTPPGVGMGMKPPRYLKPGDVVELGIEGLGTQKQNVRADI

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=202, Percent_Identity=50.4950495049505, Blast_Score=221, Evalue=4e-58,
Organism=Homo sapiens, GI40786394, Length=202, Percent_Identity=49.5049504950495, Blast_Score=215, Evalue=3e-56,
Organism=Homo sapiens, GI66348062, Length=201, Percent_Identity=39.3034825870647, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI215422413, Length=201, Percent_Identity=39.3034825870647, Blast_Score=147, Evalue=8e-36,
Organism=Homo sapiens, GI13654274, Length=208, Percent_Identity=38.4615384615385, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1787428, Length=180, Percent_Identity=37.2222222222222, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=210, Percent_Identity=35.2380952380952, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6324161, Length=229, Percent_Identity=31.0043668122271, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28572127, Length=283, Percent_Identity=42.4028268551237, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24663695, Length=287, Percent_Identity=31.3588850174216, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=35.8490566037736, Blast_Score=143, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30068; Mature: 30068

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLRYGETGQEKPGLLDADGNIRDLSAHISDLSGGALNPEALAKLGSLDVNSLPKVEGN
CCCEECCCCCCCCCCEEECCCCEEHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCC
PRLGPCVAGTGKFICIGLNYSDHAAETGAAVPSEPIIFMKATSAIVGPNDDLIIPRGSEK
CCCCCEEECCCCEEEEECCCCHHHHHCCCCCCCCCEEEEEECCEEECCCCCEEEECCCCC
TDWEVELGIVIGKTAKYVSEDNALDYVAGYCTIHDVSERAFQIERQGQWTKGKSCDTFGP
CCEEEEEEEEECCCHHHHCCCCCEEEEEEEEEEEEHHHHHEEHHCCCCCCCCCCCCCCCC
TGPWLVTKDEIADPENLGMWLTVNGETMQNGSSKTMIYGIRHLVSYLSQFMSLQPGDIIS
CCCEEEEHHHCCCHHHCCEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGMGMKPPRYLKPGDVVELGIEGLGTQKQNVRADI
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFLRYGETGQEKPGLLDADGNIRDLSAHISDLSGGALNPEALAKLGSLDVNSLPKVEGN
CCCEECCCCCCCCCCEEECCCCEEHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCC
PRLGPCVAGTGKFICIGLNYSDHAAETGAAVPSEPIIFMKATSAIVGPNDDLIIPRGSEK
CCCCCEEECCCCEEEEECCCCHHHHHCCCCCCCCCEEEEEECCEEECCCCCEEEECCCCC
TDWEVELGIVIGKTAKYVSEDNALDYVAGYCTIHDVSERAFQIERQGQWTKGKSCDTFGP
CCEEEEEEEEECCCHHHHCCCCCEEEEEEEEEEEEHHHHHEEHHCCCCCCCCCCCCCCCC
TGPWLVTKDEIADPENLGMWLTVNGETMQNGSSKTMIYGIRHLVSYLSQFMSLQPGDIIS
CCCEEEEHHHCCCHHHCCEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGMGMKPPRYLKPGDVVELGIEGLGTQKQNVRADI
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA