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The map label for this gene is qorA [H]

Identifier: 110635734

GI number: 110635734

Start: 3682935

End: 3683942

Strand: Reverse

Name: qorA [H]

Synonym: Meso_3406

Alternate gene names: 110635734

Gene position: 3683942-3682935 (Counterclockwise)

Preceding gene: 110635737

Following gene: 110635733

Centisome position: 83.49

GC content: 62.9

Gene sequence:

>1008_bases
ATGACGTCAGACGAGATCCCCGACAAGATGACGGCAGTTGCTATCACCGAGCATGGCGGCCCGATGGTGCTTAAGCCCGA
AGAGCGGCCGGTGCCCAAGCCAGGTTCTGGCGAGATCCTGATCAAGGTGAGGGCTGCGGGCGTGAATCGGCCGGATGTGG
CGCAGCGCAAGGGCGTCTACCCGCCGCCGCCGGGGGCCTCTGATCTGCCTGGGCTTGAAGTCTCGGGTATCGTCGCCGCC
ACCGGAGAAGGCGTGGAGCGGTGGCACGTGGGCGACGAGGTCACCGCGTTGACGCCGGGTGGCGGTTACGCCGAATTTTG
CGTGGTCCATGAAACCAATGCGCTTCCTATCCCGCATGGGTTCACCTTCACGGAGGCTGCAGCCCTGCCTGAGACCTTCT
TCACAGTTTGGCACAATGTTTTCGAGCGCGGGGGACTTAAGGCCGGCGAGACGCTCCTGGTCCATGGCGGTACGTCCGGC
ATCGGAACCACAGCGATCCAGGTCGCGAGCAATTTCGGCGCAAGAGTGATCGCGACGGCCGGTTCTGCCGAAAAATGCGA
GGCGTGCCTGAAGCTGGGAGCCGCTCGCGCAGTGAATTACCGCGCAGAGGATTTTGTCCTGGCCGTGAAGGAGGCGACCG
AAGGACGCGGCGCGGATGTCATTCTCGATATGGTGGGGGGCGACTATATCGACCGGAATTACGCCGCCGCCGCAATGGAC
GGGCGCATCGTGCAGATCTCGCTTCAAGGCGGATCAAAGGCAGAGGCGGATTTTTCCAAGCTCATGGTAAAGCGCCTCAC
CCATACCGGGTCCACTCTTCGCCCGCGCACCATCAAGTTCAAGGCCCATATCGCCGCCGAGCTCGAAGCGCATGTCTGGC
CGCTGCTTGCTGCACGCAAAGTGGCGCCGGTGATGGACACGATCTTTCCGCTGCGCGAGGCCTGGAGGGCGCATGAGCGC
ATGGAGGAAGGCGCCCATATCGGCAAGATCGTGCTCGATGTGGTCTGA

Upstream 100 bases:

>100_bases
TCTTTGCTGCAAGCGCAATGACAATACATAACGGGCCGGACGCGAGGCAACGCATTCCTGCCGACGCAGTTGAGGAAGAA
TTGCAAAAGAAGGCTTTGCT

Downstream 100 bases:

>100_bases
GTGGTGCTTCCGCCCTGGCTGTGCGCGTGATAAGGCCGGCGCCCATGAGCCGATTTATCATTCTTCTGGGCGGTGAGATC
CGACCTACCCCTCAGCTGCT

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTSDEIPDKMTAVAITEHGGPMVLKPEERPVPKPGSGEILIKVRAAGVNRPDVAQRKGVYPPPPGASDLPGLEVSGIVAA
TGEGVERWHVGDEVTALTPGGGYAEFCVVHETNALPIPHGFTFTEAAALPETFFTVWHNVFERGGLKAGETLLVHGGTSG
IGTTAIQVASNFGARVIATAGSAEKCEACLKLGAARAVNYRAEDFVLAVKEATEGRGADVILDMVGGDYIDRNYAAAAMD
GRIVQISLQGGSKAEADFSKLMVKRLTHTGSTLRPRTIKFKAHIAAELEAHVWPLLAARKVAPVMDTIFPLREAWRAHER
MEEGAHIGKIVLDVV

Sequences:

>Translated_335_residues
MTSDEIPDKMTAVAITEHGGPMVLKPEERPVPKPGSGEILIKVRAAGVNRPDVAQRKGVYPPPPGASDLPGLEVSGIVAA
TGEGVERWHVGDEVTALTPGGGYAEFCVVHETNALPIPHGFTFTEAAALPETFFTVWHNVFERGGLKAGETLLVHGGTSG
IGTTAIQVASNFGARVIATAGSAEKCEACLKLGAARAVNYRAEDFVLAVKEATEGRGADVILDMVGGDYIDRNYAAAAMD
GRIVQISLQGGSKAEADFSKLMVKRLTHTGSTLRPRTIKFKAHIAAELEAHVWPLLAARKVAPVMDTIFPLREAWRAHER
MEEGAHIGKIVLDVV
>Mature_334_residues
TSDEIPDKMTAVAITEHGGPMVLKPEERPVPKPGSGEILIKVRAAGVNRPDVAQRKGVYPPPPGASDLPGLEVSGIVAAT
GEGVERWHVGDEVTALTPGGGYAEFCVVHETNALPIPHGFTFTEAAALPETFFTVWHNVFERGGLKAGETLLVHGGTSGI
GTTAIQVASNFGARVIATAGSAEKCEACLKLGAARAVNYRAEDFVLAVKEATEGRGADVILDMVGGDYIDRNYAAAAMDG
RIVQISLQGGSKAEADFSKLMVKRLTHTGSTLRPRTIKFKAHIAAELEAHVWPLLAARKVAPVMDTIFPLREAWRAHERM
EEGAHIGKIVLDVV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=42.7272727272727, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=42.7272727272727, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=30.6990881458967, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=30.6990881458967, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI24308257, Length=345, Percent_Identity=28.9855072463768, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=34.9753694581281, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=26.8608414239482, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI28557745, Length=355, Percent_Identity=29.8591549295775, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI41872631, Length=314, Percent_Identity=29.2993630573248, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI47519420, Length=339, Percent_Identity=28.6135693215339, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI197927207, Length=191, Percent_Identity=28.2722513089005, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI90669511, Length=211, Percent_Identity=27.4881516587678, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=31.6923076923077, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI226510941, Length=231, Percent_Identity=26.4069264069264, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=337, Percent_Identity=26.4094955489614, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=318, Percent_Identity=27.0440251572327, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=362, Percent_Identity=21.8232044198895, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=370, Percent_Identity=24.8648648648649, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536829, Length=160, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=340, Percent_Identity=30, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323961, Length=357, Percent_Identity=26.0504201680672, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324486, Length=357, Percent_Identity=25.2100840336134, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=357, Percent_Identity=24.9299719887955, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=305, Percent_Identity=25.9016393442623, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI221330659, Length=248, Percent_Identity=28.2258064516129, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19920632, Length=248, Percent_Identity=28.2258064516129, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24581345, Length=263, Percent_Identity=26.9961977186312, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35567; Mature: 35436

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDEIPDKMTAVAITEHGGPMVLKPEERPVPKPGSGEILIKVRAAGVNRPDVAQRKGVY
CCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCC
PPPPGASDLPGLEVSGIVAATGEGVERWHVGDEVTALTPGGGYAEFCVVHETNALPIPHG
CCCCCCCCCCCCEECEEEEECCCCCEEEECCCCEEEECCCCCCEEEEEEECCCCCCCCCC
FTFTEAAALPETFFTVWHNVFERGGLKAGETLLVHGGTSGIGTTAIQVASNFGARVIATA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEC
GSAEKCEACLKLGAARAVNYRAEDFVLAVKEATEGRGADVILDMVGGDYIDRNYAAAAMD
CCHHHHHHHHHHCHHHHCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECC
GRIVQISLQGGSKAEADFSKLMVKRLTHTGSTLRPRTIKFKAHIAAELEAHVWPLLAARK
CEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHH
VAPVMDTIFPLREAWRAHERMEEGAHIGKIVLDVV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEHEEEEEC
>Mature Secondary Structure 
TSDEIPDKMTAVAITEHGGPMVLKPEERPVPKPGSGEILIKVRAAGVNRPDVAQRKGVY
CCCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHCCCC
PPPPGASDLPGLEVSGIVAATGEGVERWHVGDEVTALTPGGGYAEFCVVHETNALPIPHG
CCCCCCCCCCCCEECEEEEECCCCCEEEECCCCEEEECCCCCCEEEEEEECCCCCCCCCC
FTFTEAAALPETFFTVWHNVFERGGLKAGETLLVHGGTSGIGTTAIQVASNFGARVIATA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEC
GSAEKCEACLKLGAARAVNYRAEDFVLAVKEATEGRGADVILDMVGGDYIDRNYAAAAMD
CCHHHHHHHHHHCHHHHCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECC
GRIVQISLQGGSKAEADFSKLMVKRLTHTGSTLRPRTIKFKAHIAAELEAHVWPLLAARK
CEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHH
VAPVMDTIFPLREAWRAHERMEEGAHIGKIVLDVV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]