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The map label for this gene is xerC [H]

Identifier: 110635731

GI number: 110635731

Start: 3679425

End: 3680366

Strand: Reverse

Name: xerC [H]

Synonym: Meso_3403

Alternate gene names: 110635731

Gene position: 3680366-3679425 (Counterclockwise)

Preceding gene: 110635732

Following gene: 110635730

Centisome position: 83.41

GC content: 64.01

Gene sequence:

>942_bases
ATGAGCGAAGAGTTTCTCGTTACCGCAAAACCTGAACTGCTGAAGGCGCGCGCAGAATGGCTTTCTTCTCTGAAGGAGGA
GAGACGGCTGGCCCCGCTGACGCTTGATGCCTATGAGCGCGATACGAGGCAGTTCCTGCAATTCCTGACGCGTCATGGCG
GCGGCGCTCCGGGCCTTTGCGATATCGCTGCGCTGCGTCCAGCGGATCTGCGAGCCTTTCTCGCCGCGCGCAGGATTGAT
GGCGCAGGCGCGCGCACGCTGGGCCGAGGTCTTGCCGGGGTTCGCTCCTTTCTCCGCTTTCTTGAAAAGCGGGGGCTCGC
CAATGCTGCCGGCGCCGGAGCGCTAAGGGCCCCCCGCGCGCCCAAGGGACTGCCGAAACCATTGACCGCCGCGGACGCAA
AGCGTGTCACCTCCGGTGAGGGCCAGCTTGCGGAAGAGCCTTGGATCGCGGCCCGCAACGCCGCCGTTTTTGCGCTGCTT
TATGGCTCGGGCCTGCGCATTGGCGAGGCCCTGGGCCTTAAAGGAGTGGATATCGCGGCGCTCCGCAGCGGCTCGCTGAG
GGTGACCGGCAAGGGCAGCAAGACGCGGGTCGTGCCGGTCCTGCCGGTTGTGGGAGAAGCCGTCGCCGAATACCAGCGCC
TTTGTCCGTACCATTTGGAAGCCGAGGCGCCGCTTTTCCGCGGAGCACGCGGCGGCGCATTGCAGCCCGCTATTATCCAG
CGTGAGATGCAGAAGATGCGGTCCGCGCTCAACCTGCCGGATACGGCAACACCCCACGCGCTGCGTCACTCCTTTGCAAC
GCATCTTTTGGGCCGTGGTGGTGATTTGCGCGCGATCCAGGAGCTATTGGGTCACGCAAGTCTCTCGACGACGCAAGTCT
ATACAGCCGTCGACACCTCTCGGTTGCTCGAAATCTACGAAAATGCGCATCCGCGCCCCTGA

Upstream 100 bases:

>100_bases
GGAGCTCGAAATGCTGCGGGAGGAAATCGAGGGCCGGTGAAGGATAGCGATGAAGCTTTCTTCACGCGATGATAACCGGC
ACCATCGATAGTATGGCTCG

Downstream 100 bases:

>100_bases
GCGGCCAATTTCGCCTCTTTCCCGCGTTATCGGGTGAGCGCATGAAAAAGCATCTTGTCCGTTTCCGCCGCCTCTGGTGG
CTTCTGCCTGCCTGCCTGAG

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSEEFLVTAKPELLKARAEWLSSLKEERRLAPLTLDAYERDTRQFLQFLTRHGGGAPGLCDIAALRPADLRAFLAARRID
GAGARTLGRGLAGVRSFLRFLEKRGLANAAGAGALRAPRAPKGLPKPLTAADAKRVTSGEGQLAEEPWIAARNAAVFALL
YGSGLRIGEALGLKGVDIAALRSGSLRVTGKGSKTRVVPVLPVVGEAVAEYQRLCPYHLEAEAPLFRGARGGALQPAIIQ
REMQKMRSALNLPDTATPHALRHSFATHLLGRGGDLRAIQELLGHASLSTTQVYTAVDTSRLLEIYENAHPRP

Sequences:

>Translated_313_residues
MSEEFLVTAKPELLKARAEWLSSLKEERRLAPLTLDAYERDTRQFLQFLTRHGGGAPGLCDIAALRPADLRAFLAARRID
GAGARTLGRGLAGVRSFLRFLEKRGLANAAGAGALRAPRAPKGLPKPLTAADAKRVTSGEGQLAEEPWIAARNAAVFALL
YGSGLRIGEALGLKGVDIAALRSGSLRVTGKGSKTRVVPVLPVVGEAVAEYQRLCPYHLEAEAPLFRGARGGALQPAIIQ
REMQKMRSALNLPDTATPHALRHSFATHLLGRGGDLRAIQELLGHASLSTTQVYTAVDTSRLLEIYENAHPRP
>Mature_312_residues
SEEFLVTAKPELLKARAEWLSSLKEERRLAPLTLDAYERDTRQFLQFLTRHGGGAPGLCDIAALRPADLRAFLAARRIDG
AGARTLGRGLAGVRSFLRFLEKRGLANAAGAGALRAPRAPKGLPKPLTAADAKRVTSGEGQLAEEPWIAARNAAVFALLY
GSGLRIGEALGLKGVDIAALRSGSLRVTGKGSKTRVVPVLPVVGEAVAEYQRLCPYHLEAEAPLFRGARGGALQPAIIQR
EMQKMRSALNLPDTATPHALRHSFATHLLGRGGDLRAIQELLGHASLSTTQVYTAVDTSRLLEIYENAHPRP

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=293, Percent_Identity=34.8122866894198, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789261, Length=307, Percent_Identity=35.5048859934853, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33609; Mature: 33478

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: PS50003 PH_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEFLVTAKPELLKARAEWLSSLKEERRLAPLTLDAYERDTRQFLQFLTRHGGGAPGLC
CCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCH
DIAALRPADLRAFLAARRIDGAGARTLGRGLAGVRSFLRFLEKRGLANAAGAGALRAPRA
HHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PKGLPKPLTAADAKRVTSGEGQLAEEPWIAARNAAVFALLYGSGLRIGEALGLKGVDIAA
CCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHCCCCCCHHE
LRSGSLRVTGKGSKTRVVPVLPVVGEAVAEYQRLCPYHLEAEAPLFRGARGGALQPAIIQ
ECCCCEEEECCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCHHHHH
REMQKMRSALNLPDTATPHALRHSFATHLLGRGGDLRAIQELLGHASLSTTQVYTAVDTS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
RLLEIYENAHPRP
HHHHHHHCCCCCC
>Mature Secondary Structure 
SEEFLVTAKPELLKARAEWLSSLKEERRLAPLTLDAYERDTRQFLQFLTRHGGGAPGLC
CCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCH
DIAALRPADLRAFLAARRIDGAGARTLGRGLAGVRSFLRFLEKRGLANAAGAGALRAPRA
HHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PKGLPKPLTAADAKRVTSGEGQLAEEPWIAARNAAVFALLYGSGLRIGEALGLKGVDIAA
CCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHCCCCCCHHE
LRSGSLRVTGKGSKTRVVPVLPVVGEAVAEYQRLCPYHLEAEAPLFRGARGGALQPAIIQ
ECCCCEEEECCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCHHHHH
REMQKMRSALNLPDTATPHALRHSFATHLLGRGGDLRAIQELLGHASLSTTQVYTAVDTS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
RLLEIYENAHPRP
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]