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The map label for this gene is 110635675

Identifier: 110635675

GI number: 110635675

Start: 3618458

End: 3618754

Strand: Reverse

Name: 110635675

Synonym: Meso_3347

Alternate gene names: NA

Gene position: 3618754-3618458 (Counterclockwise)

Preceding gene: 110635677

Following gene: 110635674

Centisome position: 82.01

GC content: 53.87

Gene sequence:

>297_bases
ATGGCAAGGCAGAAACTCGACAGGAAAGAAATTGAAAACGGGCTGTCGGAACTCGATGAGTGGGAGCTTGCGGAAGGCGG
CAATGCGATCCACCGGCGGTTCGTCTTTTCAAATTTCAACGAGGCTTTCGGCTTCATGACGCGGGCAGCGCTTGCAGCGG
AAAAGCTCGATCACCATCCCGAATGGACGAATGTCTACAAAACCGTCGATGTGACCCTCACCACGCATGCCTCCGGCGGA
TTGACGGAGCTCGATTTCAAGCTGGCCAAGAAGATGAATGCTTACGCAGCCAAATAG

Upstream 100 bases:

>100_bases
CAGATATTGCCTAGGCAGACGAAAAGGATGGCGATGCGGGGCGGTTCGCTCATGATTGAGGTATTATCCTTCTGCCAATG
CGATAGCATGGAGATTATTC

Downstream 100 bases:

>100_bases
GTGCCGCCGCGGCAAGGATTGCATTTACCAAGGCCCTTCCCCACATCCCGGCTGAGGAGTGGCTCGATGGACAACGTGAA
AATTGGCGAGATCCTGGCTC

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MARQKLDRKEIENGLSELDEWELAEGGNAIHRRFVFSNFNEAFGFMTRAALAAEKLDHHPEWTNVYKTVDVTLTTHASGG
LTELDFKLAKKMNAYAAK

Sequences:

>Translated_98_residues
MARQKLDRKEIENGLSELDEWELAEGGNAIHRRFVFSNFNEAFGFMTRAALAAEKLDHHPEWTNVYKTVDVTLTTHASGG
LTELDFKLAKKMNAYAAK
>Mature_97_residues
ARQKLDRKEIENGLSELDEWELAEGGNAIHRRFVFSNFNEAFGFMTRAALAAEKLDHHPEWTNVYKTVDVTLTTHASGGL
TELDFKLAKKMNAYAAK

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI4557831, Length=77, Percent_Identity=55.8441558441558, Blast_Score=92, Evalue=1e-19,
Organism=Homo sapiens, GI134133240, Length=84, Percent_Identity=54.7619047619048, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115533705, Length=104, Percent_Identity=50, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45549100, Length=76, Percent_Identity=52.6315789473684, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_MESSB (Q11D07)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_675883.1
- ProteinModelPortal:   Q11D07
- SMR:   Q11D07
- STRING:   Q11D07
- GeneID:   4181724
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3347
- NMPDR:   fig|266779.1.peg.1180
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   FNVYSRV
- ProtClustDB:   CLSK506112
- BioCyc:   MSP266779:MESO_3347-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11115; Mature: 10983

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQKLDRKEIENGLSELDEWELAEGGNAIHRRFVFSNFNEAFGFMTRAALAAEKLDHHP
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
EWTNVYKTVDVTLTTHASGGLTELDFKLAKKMNAYAAK
CCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARQKLDRKEIENGLSELDEWELAEGGNAIHRRFVFSNFNEAFGFMTRAALAAEKLDHHP
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
EWTNVYKTVDVTLTTHASGGLTELDFKLAKKMNAYAAK
CCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA