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The map label for this gene is yafC [H]

Identifier: 110635646

GI number: 110635646

Start: 3585723

End: 3586604

Strand: Reverse

Name: yafC [H]

Synonym: Meso_3318

Alternate gene names: 110635646

Gene position: 3586604-3585723 (Counterclockwise)

Preceding gene: 110635649

Following gene: 110635640

Centisome position: 81.28

GC content: 66.21

Gene sequence:

>882_bases
ATGGATTGGGACGATGTCCGTGTGTTCCTCGCGGTCGCCCGCGCCGGTCAGATACTCGGCGCGGCCAGGCGGCTCGGCCT
CAACCACGCCACTGTTTCCCGGCGCGTGGCCGCGCTTGAGGACGCCGCCGGCGCAAAGCTTTTCCGCAGGCTTACCACAG
GAAGCGAATTGACGCCGGCCGGCGAGCGCCTGCTGGCGGCGGCGGAGCGCATGGAAGCCGATATGATTGCCGCCCGCGCC
GAGATCGCAGGCGAGGGCGAGGACATTTCGGGCAGCGTTCGCATCGGCGCGCCGGACGGTTTTGGCGTAGCCTTCCTCGC
GCCGCGGCTGTGGCGGCTGACAGAACGCCACCCGCGGCTTTCAATCCAACTCGTGCCGGTCCCGCGTTCCCTGTCGTTGT
CGCGGCGGGAGGCCGACATCGCCATCACCGTCGATCGCCCCACCGAGGGAAGGCTGGTGGCATCCAAGCTCGTGGACTAT
TCGCTGGGCCTTTTTGCCTCAAAAGCCTATGCGGCGGGGCACGGCCTGCCGCAGAACGCGGCGGAGCTGGCGCACCATAG
GCTCGTCGGCTATGTGCCGGATCTCGTCTTCAGCCCGACGCTCGATTATGCGGCGGAAATCTCGGAACATTGGGATGCCG
CTTTTGCTGTCTCCTCCGCCATGGGTCAGGTGGAGGCGGTGCGCGCCGGCGCGGGCATAGGTATCCTGCACTGCTTCATC
GCACGCGGCATGGAGGATCTGGTTGCGGTTCCCTTCGCGCAGCCCATCCGGCGTAGCTATTGGCTGGTTTTTCACGAATC
CATGAGGATGACCCGACAGATACAGGCCGCCGCCGCCTTCATCGGCGAGATCGTGGCGCAGGAACGCAGGATCTTCGCCT
GA

Upstream 100 bases:

>100_bases
TTTGACGCGTTGAATGCAACGCGAGGAAAATCGAAGCCGTTGTGCAGAAATTAAAGCGCTGCTAGCAAGTGCGTGCATAA
AATCATGTAAGGTGGCGCCT

Downstream 100 bases:

>100_bases
TCAACGCCGGGCCCGGGCCCCTTCTATGGCGAGGGCGAGAAGCGCCTGGCGGCTGACGGGCTCAGCCACGGCCGGGTGCT
GGCGTGATTTCAGGATCGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDWDDVRVFLAVARAGQILGAARRLGLNHATVSRRVAALEDAAGAKLFRRLTTGSELTPAGERLLAAAERMEADMIAARA
EIAGEGEDISGSVRIGAPDGFGVAFLAPRLWRLTERHPRLSIQLVPVPRSLSLSRREADIAITVDRPTEGRLVASKLVDY
SLGLFASKAYAAGHGLPQNAAELAHHRLVGYVPDLVFSPTLDYAAEISEHWDAAFAVSSAMGQVEAVRAGAGIGILHCFI
ARGMEDLVAVPFAQPIRRSYWLVFHESMRMTRQIQAAAAFIGEIVAQERRIFA

Sequences:

>Translated_293_residues
MDWDDVRVFLAVARAGQILGAARRLGLNHATVSRRVAALEDAAGAKLFRRLTTGSELTPAGERLLAAAERMEADMIAARA
EIAGEGEDISGSVRIGAPDGFGVAFLAPRLWRLTERHPRLSIQLVPVPRSLSLSRREADIAITVDRPTEGRLVASKLVDY
SLGLFASKAYAAGHGLPQNAAELAHHRLVGYVPDLVFSPTLDYAAEISEHWDAAFAVSSAMGQVEAVRAGAGIGILHCFI
ARGMEDLVAVPFAQPIRRSYWLVFHESMRMTRQIQAAAAFIGEIVAQERRIFA
>Mature_293_residues
MDWDDVRVFLAVARAGQILGAARRLGLNHATVSRRVAALEDAAGAKLFRRLTTGSELTPAGERLLAAAERMEADMIAARA
EIAGEGEDISGSVRIGAPDGFGVAFLAPRLWRLTERHPRLSIQLVPVPRSLSLSRREADIAITVDRPTEGRLVASKLVDY
SLGLFASKAYAAGHGLPQNAAELAHHRLVGYVPDLVFSPTLDYAAEISEHWDAAFAVSSAMGQVEAVRAGAGIGILHCFI
ARGMEDLVAVPFAQPIRRSYWLVFHESMRMTRQIQAAAAFIGEIVAQERRIFA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=26.2975778546713, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI145693193, Length=234, Percent_Identity=26.4957264957265, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=24.406779661017, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081978, Length=181, Percent_Identity=30.939226519337, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789440, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789506, Length=117, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=173, Percent_Identity=25.4335260115607, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788706, Length=185, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31731; Mature: 31731

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWDDVRVFLAVARAGQILGAARRLGLNHATVSRRVAALEDAAGAKLFRRLTTGSELTPA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GERLLAAAERMEADMIAARAEIAGEGEDISGSVRIGAPDGFGVAFLAPRLWRLTERHPRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCE
SIQLVPVPRSLSLSRREADIAITVDRPTEGRLVASKLVDYSLGLFASKAYAAGHGLPQNA
EEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AELAHHRLVGYVPDLVFSPTLDYAAEISEHWDAAFAVSSAMGQVEAVRAGAGIGILHCFI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ARGMEDLVAVPFAQPIRRSYWLVFHESMRMTRQIQAAAAFIGEIVAQERRIFA
HHCHHHHHHCCCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDWDDVRVFLAVARAGQILGAARRLGLNHATVSRRVAALEDAAGAKLFRRLTTGSELTPA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GERLLAAAERMEADMIAARAEIAGEGEDISGSVRIGAPDGFGVAFLAPRLWRLTERHPRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCE
SIQLVPVPRSLSLSRREADIAITVDRPTEGRLVASKLVDYSLGLFASKAYAAGHGLPQNA
EEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AELAHHRLVGYVPDLVFSPTLDYAAEISEHWDAAFAVSSAMGQVEAVRAGAGIGILHCFI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ARGMEDLVAVPFAQPIRRSYWLVFHESMRMTRQIQAAAAFIGEIVAQERRIFA
HHCHHHHHHCCCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]