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The map label for this gene is ruvA

Identifier: 110635507

GI number: 110635507

Start: 3449851

End: 3450471

Strand: Reverse

Name: ruvA

Synonym: Meso_3178

Alternate gene names: 110635507

Gene position: 3450471-3449851 (Counterclockwise)

Preceding gene: 110635508

Following gene: 110635506

Centisome position: 78.2

GC content: 65.7

Gene sequence:

>621_bases
ATGATCGGAAAGCTGAAGGGTGTTCTCGATGAGATCGGAGAGGATCATTGCGTGGTCGATGTCGGTGGCGTCGGTTACGT
CGCCCACTGCTCGGCACGCAGCCTATCGACCCTCGGCAGCGTCGGAACGCCGGTAACGCTCTTCATCGAGACCTATGTCC
GCGAGGACATGATCCGCCTTTATGGCTTCCGGACGGTGCTGGAGCGCGAATGGTTCCGGCTGCTCCAGAACAATGTCCAG
GGCGTGGGCGCAAAGGTCGCGCTTTCGGTGCTGTCTACCCTCACGCCGTCCGAGCTGGCCAATGCCATCGCCCTTAGGGA
TATCGCCACGGTGGCGCGTGCGCCGGGCGTCGGCAGAAAGGTGGCCGAGCGCATCGTCACGGAACTGAAGAGCAAGGCGC
CGGCTTTCGCGGGCGAGGCCGCGGGCGCAATCGGGCTCAAGCAGGACCTCGGCGAGGGTGTCGCCCCGGCGCCCGTCTCG
GACGCCGTGTCCGCACTGGCCAATCTCGGCTATTCGCGCGATATCGCGGCGAATGCCGTCGCCGCCGCGCTCAAATCCGC
GGGCGAAGGCGCGGATACGGGCACGCTGATCCGCCTGGGTTTGAAGGAACTGGCGCGGTAG

Upstream 100 bases:

>100_bases
TCTTCGATGGCGACGATGCGGCAGATGCCATCGCGGTCGCGATCTGCCATGCGCATCACCGGCAGTCGCCCGCTTGGCGA
CTTGCTCTGGAGGCTCAGCC

Downstream 100 bases:

>100_bases
GGCGCGGCAATCGAAGTGGAGTGCTCCTTACGTCAGTCGGGTAAGGAGACCAAAAAAGGTAAGGCCATGGGTATCCGGGC
AACCATCACGTCCGAGGGGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIGKLKGVLDEIGEDHCVVDVGGVGYVAHCSARSLSTLGSVGTPVTLFIETYVREDMIRLYGFRTVLEREWFRLLQNNVQ
GVGAKVALSVLSTLTPSELANAIALRDIATVARAPGVGRKVAERIVTELKSKAPAFAGEAAGAIGLKQDLGEGVAPAPVS
DAVSALANLGYSRDIAANAVAAALKSAGEGADTGTLIRLGLKELAR

Sequences:

>Translated_206_residues
MIGKLKGVLDEIGEDHCVVDVGGVGYVAHCSARSLSTLGSVGTPVTLFIETYVREDMIRLYGFRTVLEREWFRLLQNNVQ
GVGAKVALSVLSTLTPSELANAIALRDIATVARAPGVGRKVAERIVTELKSKAPAFAGEAAGAIGLKQDLGEGVAPAPVS
DAVSALANLGYSRDIAANAVAAALKSAGEGADTGTLIRLGLKELAR
>Mature_206_residues
MIGKLKGVLDEIGEDHCVVDVGGVGYVAHCSARSLSTLGSVGTPVTLFIETYVREDMIRLYGFRTVLEREWFRLLQNNVQ
GVGAKVALSVLSTLTPSELANAIALRDIATVARAPGVGRKVAERIVTELKSKAPAFAGEAAGAIGLKQDLGEGVAPAPVS
DAVSALANLGYSRDIAANAVAAALKSAGEGADTGTLIRLGLKELAR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=208, Percent_Identity=34.1346153846154, Blast_Score=106, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_MESSB (Q11DH5)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_675715.1
- ProteinModelPortal:   Q11DH5
- SMR:   Q11DH5
- STRING:   Q11DH5
- GeneID:   4182268
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3178
- NMPDR:   fig|266779.1.peg.107
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- BioCyc:   MSP266779:MESO_3178-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21326; Mature: 21326

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLKGVLDEIGEDHCVVDVGGVGYVAHCSARSLSTLGSVGTPVTLFIETYVREDMIRL
CCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YGFRTVLEREWFRLLQNNVQGVGAKVALSVLSTLTPSELANAIALRDIATVARAPGVGRK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHH
VAERIVTELKSKAPAFAGEAAGAIGLKQDLGEGVAPAPVSDAVSALANLGYSRDIAANAV
HHHHHHHHHHHHCCCCCCHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
AAALKSAGEGADTGTLIRLGLKELAR
HHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKLKGVLDEIGEDHCVVDVGGVGYVAHCSARSLSTLGSVGTPVTLFIETYVREDMIRL
CCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YGFRTVLEREWFRLLQNNVQGVGAKVALSVLSTLTPSELANAIALRDIATVARAPGVGRK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHH
VAERIVTELKSKAPAFAGEAAGAIGLKQDLGEGVAPAPVSDAVSALANLGYSRDIAANAV
HHHHHHHHHHHHCCCCCCHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
AAALKSAGEGADTGTLIRLGLKELAR
HHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA