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The map label for this gene is yajO [H]

Identifier: 110635458

GI number: 110635458

Start: 3395583

End: 3396560

Strand: Reverse

Name: yajO [H]

Synonym: Meso_3129

Alternate gene names: 110635458

Gene position: 3396560-3395583 (Counterclockwise)

Preceding gene: 110635467

Following gene: 110635456

Centisome position: 76.98

GC content: 61.35

Gene sequence:

>978_bases
ATGGAATATGTCAATCTCGGCCGTTCGGGTCTGAAGGTTTCTCGCCTGTCCTTGGGCTGTATGACCTTCGGTTCGGCCAA
ATGGGCTTCATGGGTTCTGGACGAGCAGGCCGCGACGCCGATCATCGAGCGCGCGCTGGATCTGGGCATCAATTTCTTCG
ATCTCGCCGACGTGTATTCGCTGGGGGAGAGCGAGGTGGTGACCGGCCGGGTGCTGAAGCGGCTTCGGGCGAGGCACCAG
CTCGTGATTGCCACCAAACTCTACAATGCGATGAGCGACGATCCAAACGACCGGGGCCTGAGCCGGAAGCATATATTCGA
AGCGGTCGACGCGAGCCTGAAACGCCTTGGCACCGACTATATCGATCTTTATCAGCTGCATCGCTTCGATTACGAAACAC
CGCTTGAAGAAACGCTCGACGCGCTCAACGACCTCGTGCGGGCCGGCAAGGTGCGCTATCTTGGGGCGTCGTCCATGTTC
GCCTGGCAGTTCATGAAGGCGCTTGGCCTGCAGCGCCAGCACGGCTGGGCGCCCTTCGTTTCAATGCAGCCTCATTACAA
CCTCATCTACCGCGAGGAGGAGCGGGAGATGCTGCCGCTTTGCCGCAGCGAAGGGATCGGCGTGATTCCCTGGAGCCCGC
TGGCGCGCGGCCGCCTGGCCGGCCGCAGCGGCGATGAAGCCACGTTACGCGCTCAAACGGACCGCACACAGGTAAAGCTC
TATGGATCGACCGAGGAACAGGATGCAAAAGTGATTGCCGCCGTGCGCGAAGTTGCCACGCGCCAAGGGCGGCCAATGGC
GCAAGTCGCTTATGCCTGGGTTGCCTCGCGGCCCGGCATCACCGCGCCGATCGTGGGCATTTCACGGTTGGAACAGTTCG
ACGATGCCATTGCCGCTTTGGATGTAGAGCTGAGCGATGAGGACGTTGCTTTGCTCGAAGCGCACTACCAGCCGAAGCGC
GTCGCCGGACACACCTAG

Upstream 100 bases:

>100_bases
GCGCATTTAGCAAAAAGGCTAATGTGGAGCGTTGCCGCCGGCCGCCAGCTTCTGCAATAAATGTGCGGGCGAAGCAGGTC
AGTTTGGAAAAGGTGTATTG

Downstream 100 bases:

>100_bases
CTCATGCGAGGAAGCCGTGAGCCTTGGCGAAGGCCTTCAGGCCGCGCCAGGCGTCTTCGACGGCCGTATCGTCGTAAGTC
GCGGTGAAACAGGCTTCCAG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MEYVNLGRSGLKVSRLSLGCMTFGSAKWASWVLDEQAATPIIERALDLGINFFDLADVYSLGESEVVTGRVLKRLRARHQ
LVIATKLYNAMSDDPNDRGLSRKHIFEAVDASLKRLGTDYIDLYQLHRFDYETPLEETLDALNDLVRAGKVRYLGASSMF
AWQFMKALGLQRQHGWAPFVSMQPHYNLIYREEEREMLPLCRSEGIGVIPWSPLARGRLAGRSGDEATLRAQTDRTQVKL
YGSTEEQDAKVIAAVREVATRQGRPMAQVAYAWVASRPGITAPIVGISRLEQFDDAIAALDVELSDEDVALLEAHYQPKR
VAGHT

Sequences:

>Translated_325_residues
MEYVNLGRSGLKVSRLSLGCMTFGSAKWASWVLDEQAATPIIERALDLGINFFDLADVYSLGESEVVTGRVLKRLRARHQ
LVIATKLYNAMSDDPNDRGLSRKHIFEAVDASLKRLGTDYIDLYQLHRFDYETPLEETLDALNDLVRAGKVRYLGASSMF
AWQFMKALGLQRQHGWAPFVSMQPHYNLIYREEEREMLPLCRSEGIGVIPWSPLARGRLAGRSGDEATLRAQTDRTQVKL
YGSTEEQDAKVIAAVREVATRQGRPMAQVAYAWVASRPGITAPIVGISRLEQFDDAIAALDVELSDEDVALLEAHYQPKR
VAGHT
>Mature_325_residues
MEYVNLGRSGLKVSRLSLGCMTFGSAKWASWVLDEQAATPIIERALDLGINFFDLADVYSLGESEVVTGRVLKRLRARHQ
LVIATKLYNAMSDDPNDRGLSRKHIFEAVDASLKRLGTDYIDLYQLHRFDYETPLEETLDALNDLVRAGKVRYLGASSMF
AWQFMKALGLQRQHGWAPFVSMQPHYNLIYREEEREMLPLCRSEGIGVIPWSPLARGRLAGRSGDEATLRAQTDRTQVKL
YGSTEEQDAKVIAAVREVATRQGRPMAQVAYAWVASRPGITAPIVGISRLEQFDDAIAALDVELSDEDVALLEAHYQPKR
VAGHT

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=313, Percent_Identity=34.185303514377, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI27436962, Length=313, Percent_Identity=34.185303514377, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=33.8658146964856, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI27436969, Length=311, Percent_Identity=36.3344051446945, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=36.2459546925566, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI27436971, Length=316, Percent_Identity=34.8101265822785, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI223718702, Length=286, Percent_Identity=27.972027972028, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI41152114, Length=296, Percent_Identity=29.3918918918919, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41327764, Length=288, Percent_Identity=28.8194444444444, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI223718708, Length=145, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=54.4615384615385, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=34.5565749235474, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=31.8840579710145, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=32.8267477203647, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1788081, Length=292, Percent_Identity=30.8219178082192, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994888, Length=317, Percent_Identity=26.4984227129338, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787674, Length=312, Percent_Identity=23.7179487179487, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=42.1364985163205, Blast_Score=258, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6323998, Length=318, Percent_Identity=29.559748427673, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6319958, Length=290, Percent_Identity=29.3103448275862, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319951, Length=318, Percent_Identity=29.559748427673, Blast_Score=132, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=31.2, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321052, Length=151, Percent_Identity=30.4635761589404, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=28.4403669724771, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45549126, Length=249, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646155, Length=317, Percent_Identity=30.2839116719243, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24646159, Length=224, Percent_Identity=30.3571428571429, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36398; Mature: 36398

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYVNLGRSGLKVSRLSLGCMTFGSAKWASWVLDEQAATPIIERALDLGINFFDLADVYS
CCCCCCCCCCCEEHHEEEHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
LGESEVVTGRVLKRLRARHQLVIATKLYNAMSDDPNDRGLSRKHIFEAVDASLKRLGTDY
CCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
IDLYQLHRFDYETPLEETLDALNDLVRAGKVRYLGASSMFAWQFMKALGLQRQHGWAPFV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEE
SMQPHYNLIYREEEREMLPLCRSEGIGVIPWSPLARGRLAGRSGDEATLRAQTDRTQVKL
ECCCCCCEEEECCHHHHHHHHHCCCCEECCCCCHHCCCCCCCCCCCCEEEEECCCEEEEE
YGSTEEQDAKVIAAVREVATRQGRPMAQVAYAWVASRPGITAPIVGISRLEQFDDAIAAL
ECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHE
DVELSDEDVALLEAHYQPKRVAGHT
EEEECCCCEEEHHHCCCCCCCCCCC
>Mature Secondary Structure
MEYVNLGRSGLKVSRLSLGCMTFGSAKWASWVLDEQAATPIIERALDLGINFFDLADVYS
CCCCCCCCCCCEEHHEEEHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
LGESEVVTGRVLKRLRARHQLVIATKLYNAMSDDPNDRGLSRKHIFEAVDASLKRLGTDY
CCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
IDLYQLHRFDYETPLEETLDALNDLVRAGKVRYLGASSMFAWQFMKALGLQRQHGWAPFV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEE
SMQPHYNLIYREEEREMLPLCRSEGIGVIPWSPLARGRLAGRSGDEATLRAQTDRTQVKL
ECCCCCCEEEECCHHHHHHHHHCCCCEECCCCCHHCCCCCCCCCCCCEEEEECCCEEEEE
YGSTEEQDAKVIAAVREVATRQGRPMAQVAYAWVASRPGITAPIVGISRLEQFDDAIAAL
ECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHE
DVELSDEDVALLEAHYQPKRVAGHT
EEEECCCCEEEHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]