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The map label for this gene is hipO [H]

Identifier: 110635385

GI number: 110635385

Start: 3331096

End: 3332259

Strand: Reverse

Name: hipO [H]

Synonym: Meso_3056

Alternate gene names: 110635385

Gene position: 3332259-3331096 (Counterclockwise)

Preceding gene: 110635388

Following gene: 110635384

Centisome position: 75.52

GC content: 61.08

Gene sequence:

>1164_bases
ATGCCGATTGTGAACCGAGCTGCTGAACTTCAAGGTGAGGTCACCGAGTGGCGCCGGCAATTGCATCGCAACCCGGAACT
CCTCTTCGACGTGAACGAAACCGCCGCTTTCGTGAGCGACAAGCTTCGTGAGTTCGGTTGCGATGAGGTGGTGACGGGAC
TCGGACGCACGGGGGTGGTCGGCATCATTCGCGGCAGCCGCGGCGCAGGCCCGTGCATCGGTCTGCGCGCCGATATGGAT
GCATTGCCGCTTCAGGAGGCGGTCGATCGGCCTTATGCTTCTGCAGTTCCGGGCCGCATGCACGCCTGCGGGCATGATGG
CCACACCGCGATGTTGCTGGGCGCCGCCAAATATCTCGCCGAGACGCGCAATTTCGTGGGAACCGCTGCCGTTATTTTTC
AGCCCGCCGAGGAAGGCGGTGGCGGCGGGAACGAGATGGTGAAAGACGGCATGATGGAGCGCTTCGGGATCACGCGCGTC
TTCGGCATGCACAATTTGCCTGGCATGCCGGTCGGGCATTTCGGCATCAGGCCTGGGCCCATCATGGCCTCGACCGCGGA
GTTCAACATCGTCGTTGAGGGTAAGGGCGGTCACGCAGCCATGCCGCATAAGACAATCGATCCCGTTGTGACCGCCGCGC
AGATCGTCATGGGCCTTCAGACCATCGCCGCAAGATCGGCGGATCCGCTCGAATCCGTCGTCGTTTCGGTCACCAAGTTC
CATGGTGGCGATGCGCACAACATCATTCCCGACAGAGTCGAGATGGCAGGGACGATTCGGACGCTTAAAGGAGAGGTAAG
CTTGCTTGCCGAAGGGCGCCTGCGCACGATCGCGGAAGGTATTGCCCATGCCCATGGGGCGAAGGTGGCGATCGATTATG
ATCCGAACTATCCCGTGACCGTAAATAATCAGGCGGAAGCCGAATTTGCCGCACAGGTGGCTGTCGCCGTGGCGGGAGCG
GCCAATGTGGCCACCGATGTCCCACCCCTGATGGGTGGCGAGGATTTCTCCTACATGCTGCTGGCCCGGCCCGGCTGTCT
CATCTTCATCGGAAACGGCGATAGCGCCGGCCTGCACAATCCCTCCTACGACTTCAACGACGAAGCCATTCCATATGGGA
TCAGCTATTGGGTTCGGTTGGTGGAAAGTGCGCTTCCAGCGTGA

Upstream 100 bases:

>100_bases
GCGCCGTTGCGGTAGCCAATGCAATTTGTCGTTATCATGACGGGCCGCCTTTTCATTGTTTCTAAATTCCTTCGGACCGC
AAGCACAGGAAAGAGTTTTC

Downstream 100 bases:

>100_bases
AAAACTCGGGGCGGCAAAATGTCTCGGGCGGGGCGGCGAGCGGTTGCATGAAGTCCATTTCGGCTTGGCTATACCGCCGC
TACAGGGTATGAGTGCGTCA

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPIVNRAAELQGEVTEWRRQLHRNPELLFDVNETAAFVSDKLREFGCDEVVTGLGRTGVVGIIRGSRGAGPCIGLRADMD
ALPLQEAVDRPYASAVPGRMHACGHDGHTAMLLGAAKYLAETRNFVGTAAVIFQPAEEGGGGGNEMVKDGMMERFGITRV
FGMHNLPGMPVGHFGIRPGPIMASTAEFNIVVEGKGGHAAMPHKTIDPVVTAAQIVMGLQTIAARSADPLESVVVSVTKF
HGGDAHNIIPDRVEMAGTIRTLKGEVSLLAEGRLRTIAEGIAHAHGAKVAIDYDPNYPVTVNNQAEAEFAAQVAVAVAGA
ANVATDVPPLMGGEDFSYMLLARPGCLIFIGNGDSAGLHNPSYDFNDEAIPYGISYWVRLVESALPA

Sequences:

>Translated_387_residues
MPIVNRAAELQGEVTEWRRQLHRNPELLFDVNETAAFVSDKLREFGCDEVVTGLGRTGVVGIIRGSRGAGPCIGLRADMD
ALPLQEAVDRPYASAVPGRMHACGHDGHTAMLLGAAKYLAETRNFVGTAAVIFQPAEEGGGGGNEMVKDGMMERFGITRV
FGMHNLPGMPVGHFGIRPGPIMASTAEFNIVVEGKGGHAAMPHKTIDPVVTAAQIVMGLQTIAARSADPLESVVVSVTKF
HGGDAHNIIPDRVEMAGTIRTLKGEVSLLAEGRLRTIAEGIAHAHGAKVAIDYDPNYPVTVNNQAEAEFAAQVAVAVAGA
ANVATDVPPLMGGEDFSYMLLARPGCLIFIGNGDSAGLHNPSYDFNDEAIPYGISYWVRLVESALPA
>Mature_386_residues
PIVNRAAELQGEVTEWRRQLHRNPELLFDVNETAAFVSDKLREFGCDEVVTGLGRTGVVGIIRGSRGAGPCIGLRADMDA
LPLQEAVDRPYASAVPGRMHACGHDGHTAMLLGAAKYLAETRNFVGTAAVIFQPAEEGGGGGNEMVKDGMMERFGITRVF
GMHNLPGMPVGHFGIRPGPIMASTAEFNIVVEGKGGHAAMPHKTIDPVVTAAQIVMGLQTIAARSADPLESVVVSVTKFH
GGDAHNIIPDRVEMAGTIRTLKGEVSLLAEGRLRTIAEGIAHAHGAKVAIDYDPNYPVTVNNQAEAEFAAQVAVAVAGAA
NVATDVPPLMGGEDFSYMLLARPGCLIFIGNGDSAGLHNPSYDFNDEAIPYGISYWVRLVESALPA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=429, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 40897; Mature: 40766

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIVNRAAELQGEVTEWRRQLHRNPELLFDVNETAAFVSDKLREFGCDEVVTGLGRTGVV
CCCCCCHHHHCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCHHHHHHCCCCCCEE
GIIRGSRGAGPCIGLRADMDALPLQEAVDRPYASAVPGRMHACGHDGHTAMLLGAAKYLA
EEEECCCCCCCEEEEECCCCCCCHHHHHCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHH
ETRNFVGTAAVIFQPAEEGGGGGNEMVKDGMMERFGITRVFGMHNLPGMPVGHFGIRPGP
HHHHHHEEEEEEEEEHHCCCCCCHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCC
IMASTAEFNIVVEGKGGHAAMPHKTIDPVVTAAQIVMGLQTIAARSADPLESVVVSVTKF
CEEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HGGDAHNIIPDRVEMAGTIRTLKGEVSLLAEGRLRTIAEGIAHAHGAKVAIDYDPNYPVT
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCEE
VNNQAEAEFAAQVAVAVAGAANVATDVPPLMGGEDFSYMLLARPGCLIFIGNGDSAGLHN
ECCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCC
PSYDFNDEAIPYGISYWVRLVESALPA
CCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIVNRAAELQGEVTEWRRQLHRNPELLFDVNETAAFVSDKLREFGCDEVVTGLGRTGVV
CCCCCHHHHCCHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCHHHHHHCCCCCCEE
GIIRGSRGAGPCIGLRADMDALPLQEAVDRPYASAVPGRMHACGHDGHTAMLLGAAKYLA
EEEECCCCCCCEEEEECCCCCCCHHHHHCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHH
ETRNFVGTAAVIFQPAEEGGGGGNEMVKDGMMERFGITRVFGMHNLPGMPVGHFGIRPGP
HHHHHHEEEEEEEEEHHCCCCCCHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCC
IMASTAEFNIVVEGKGGHAAMPHKTIDPVVTAAQIVMGLQTIAARSADPLESVVVSVTKF
CEEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HGGDAHNIIPDRVEMAGTIRTLKGEVSLLAEGRLRTIAEGIAHAHGAKVAIDYDPNYPVT
CCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCEE
VNNQAEAEFAAQVAVAVAGAANVATDVPPLMGGEDFSYMLLARPGCLIFIGNGDSAGLHN
ECCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCC
PSYDFNDEAIPYGISYWVRLVESALPA
CCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]