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The map label for this gene is tlpA [H]

Identifier: 110635366

GI number: 110635366

Start: 3309782

End: 3310447

Strand: Reverse

Name: tlpA [H]

Synonym: Meso_3037

Alternate gene names: 110635366

Gene position: 3310447-3309782 (Counterclockwise)

Preceding gene: 110635370

Following gene: 110635365

Centisome position: 75.03

GC content: 62.76

Gene sequence:

>666_bases
ATGCCGATGAATAGGAAGTTTCCAGCGGTTGGTCTGGTCGCGCTTTCCGCGGTCGCAGGCATCATCGCCGGGGTTACCGC
CCTATACGTGATGGGTGGGCCGAATGGCAACCTCAGCGCGGGTAATGTCGAGACAGCCGCCTGTGAGGCGACGAGCCAAA
AAGCTCAGGCGCTGGATAGCGCCATTAGCGGTGAAGTAGCCGCCATGCTGCCTGCCGATCCTCCTCAATCCCTCAGCAAT
CTCGGCTTCAACGGGCCGGAGGGCGAGCCGATAACGGTAGCCGGCCTGGCCGGGAAAACACTTCTCATCAACCTCTGGGC
CACCTGGTGCGTGCCGTGCCGCACGGAAATGCCCGCGCTGGACATGCTGGAGCGCGAGATGGGCTCCGACCGTTTCGAGG
TGGTGGCCATCAATGTGGACCGTGGCGGCGACGAGAAGCCGAAGGCGTTTCTGGAGGAGACCGGAATCAAGTCGCTCGCC
TATTATCGGGACAGTTCCCTTGGAGTTTTCAACGAGCTGAAGACGCGGGGACTGGCGCTTGGCCTTCCGGTCACTCTTCT
GGTGGACGAAGATGGCTGCCTGCTGGCGCATATGAACGGGCCTGCCGAGTGGGCTAGCGAGGACGCCAAGAGGCTGATCC
GGGCCGCCGTGGGCGAGGAAGGCTGA

Upstream 100 bases:

>100_bases
TTCCATGATGGCATCGGGGCCTGAGGCAAAACGTCCGCCCCACATGCGGTTGCTGGCTTTGTTCTCGTTCATCATGGTAA
CCGGGCGCTGGAGTAAAGAA

Downstream 100 bases:

>100_bases
AGGAGCGCTTTTATGTGCATCCGCCATAGCGGATGCCATTCCTTCCTGGAACCTGCCCAAGGGTGAGCCTATTCTCAAGG
CAGCTGATGCCAGCCGAGAG

Product: redoxin

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MPMNRKFPAVGLVALSAVAGIIAGVTALYVMGGPNGNLSAGNVETAACEATSQKAQALDSAISGEVAAMLPADPPQSLSN
LGFNGPEGEPITVAGLAGKTLLINLWATWCVPCRTEMPALDMLEREMGSDRFEVVAINVDRGGDEKPKAFLEETGIKSLA
YYRDSSLGVFNELKTRGLALGLPVTLLVDEDGCLLAHMNGPAEWASEDAKRLIRAAVGEEG

Sequences:

>Translated_221_residues
MPMNRKFPAVGLVALSAVAGIIAGVTALYVMGGPNGNLSAGNVETAACEATSQKAQALDSAISGEVAAMLPADPPQSLSN
LGFNGPEGEPITVAGLAGKTLLINLWATWCVPCRTEMPALDMLEREMGSDRFEVVAINVDRGGDEKPKAFLEETGIKSLA
YYRDSSLGVFNELKTRGLALGLPVTLLVDEDGCLLAHMNGPAEWASEDAKRLIRAAVGEEG
>Mature_220_residues
PMNRKFPAVGLVALSAVAGIIAGVTALYVMGGPNGNLSAGNVETAACEATSQKAQALDSAISGEVAAMLPADPPQSLSNL
GFNGPEGEPITVAGLAGKTLLINLWATWCVPCRTEMPALDMLEREMGSDRFEVVAINVDRGGDEKPKAFLEETGIKSLAY
YRDSSLGVFNELKTRGLALGLPVTLLVDEDGCLLAHMNGPAEWASEDAKRLIRAAVGEEG

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 23087; Mature: 22955

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMNRKFPAVGLVALSAVAGIIAGVTALYVMGGPNGNLSAGNVETAACEATSQKAQALDS
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
AISGEVAAMLPADPPQSLSNLGFNGPEGEPITVAGLAGKTLLINLWATWCVPCRTEMPAL
HHCCCEEEECCCCCHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEHHHHHCCCCCCCCHH
DMLEREMGSDRFEVVAINVDRGGDEKPKAFLEETGIKSLAYYRDSSLGVFNELKTRGLAL
HHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHCCCHHHHHCCCCCCCHHHHHHHCCEEE
GLPVTLLVDEDGCLLAHMNGPAEWASEDAKRLIRAAVGEEG
CCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PMNRKFPAVGLVALSAVAGIIAGVTALYVMGGPNGNLSAGNVETAACEATSQKAQALDS
CCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
AISGEVAAMLPADPPQSLSNLGFNGPEGEPITVAGLAGKTLLINLWATWCVPCRTEMPAL
HHCCCEEEECCCCCHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEHHHHHCCCCCCCCHH
DMLEREMGSDRFEVVAINVDRGGDEKPKAFLEETGIKSLAYYRDSSLGVFNELKTRGLAL
HHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHCCCHHHHHCCCCCCCHHHHHHHCCEEE
GLPVTLLVDEDGCLLAHMNGPAEWASEDAKRLIRAAVGEEG
CCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]