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The map label for this gene is hutC [H]

Identifier: 110635305

GI number: 110635305

Start: 3235778

End: 3236506

Strand: Reverse

Name: hutC [H]

Synonym: Meso_2976

Alternate gene names: 110635305

Gene position: 3236506-3235778 (Counterclockwise)

Preceding gene: 110635311

Following gene: 110635301

Centisome position: 73.35

GC content: 55.97

Gene sequence:

>729_bases
GTGACAGCGTTTGAAAAGGGCGGATCTCAATCGAGAGTACGGCAGGTCGAGATCGAGTTGACCGGTCGAATCCTTAACGG
GTTTTATGCTCACGGGGAGAGACTGCCCTCCGAGGCCGAACTCGTCAAACAGTTCAATGTTTCCCGCCAGACCATTCATA
AGGCCCTACGAGAACTTGCAAAGTTCGGGCTTGTCGAACGAAATCGCCGTGCGGGAACGATCGTTATCCGAAAGTTCCAG
CAGACATTCGTGCTGCCCCTCACCGATATCAGCGAAGATGTTTTCAAACGCAATTCCATCTATGCGTTCAAGCTGCGTCG
GCAGACGGTTCTGCGAAACAACACCGCATTTAGCTGGCCAGATTTACCTGACGATGCGGAGGTCGTTTATGTCGAGCTCC
TGCATTATTGCGACGACGTGCCTGTCATGCTCGAGACCCGGCACATCAATCTGGGGGCCGCGCCGGATGCGCGCAACATC
GATTTTTCGACTATCGCACCCAGTCCGTGGCTGATGTCGAATATTCCGTGGTCGTCTGTCAGTCATCGCATCAGCGCCAT
TTCCAGTGGCGAAGAGCTTGCGCGTGCCCTGGACCTGACTCCGGGTGCGGCTTGCATGGCAATCGAGCGGAAAACCTATC
ATCTTGCCTTGCCGATCACGCGCGTGCGCATGGTCCTTGCCGGCGATCGCATGGATCTTCGCGGCGAGTACGTCCTGCCG
ACGTTGTGA

Upstream 100 bases:

>100_bases
TTCGTTGGCAGACGGAAGCGGCGTTTGATGGCGACTTCCCGGTCTTCACGACCGGCGGATTTGCAATAATGTCTATATGT
TATTTTTGGGGAAGTAGCTT

Downstream 100 bases:

>100_bases
TCCATGTTCACCATGCGTGCAAGCTCTCTAGCTCGATCCGGCCAGGGTATTCGGCGAGGATCGCGTAGTCATCAATTGCG
ACCTCGGCGAAGCGGCGTAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTAFEKGGSQSRVRQVEIELTGRILNGFYAHGERLPSEAELVKQFNVSRQTIHKALRELAKFGLVERNRRAGTIVIRKFQ
QTFVLPLTDISEDVFKRNSIYAFKLRRQTVLRNNTAFSWPDLPDDAEVVYVELLHYCDDVPVMLETRHINLGAAPDARNI
DFSTIAPSPWLMSNIPWSSVSHRISAISSGEELARALDLTPGAACMAIERKTYHLALPITRVRMVLAGDRMDLRGEYVLP
TL

Sequences:

>Translated_242_residues
MTAFEKGGSQSRVRQVEIELTGRILNGFYAHGERLPSEAELVKQFNVSRQTIHKALRELAKFGLVERNRRAGTIVIRKFQ
QTFVLPLTDISEDVFKRNSIYAFKLRRQTVLRNNTAFSWPDLPDDAEVVYVELLHYCDDVPVMLETRHINLGAAPDARNI
DFSTIAPSPWLMSNIPWSSVSHRISAISSGEELARALDLTPGAACMAIERKTYHLALPITRVRMVLAGDRMDLRGEYVLP
TL
>Mature_241_residues
TAFEKGGSQSRVRQVEIELTGRILNGFYAHGERLPSEAELVKQFNVSRQTIHKALRELAKFGLVERNRRAGTIVIRKFQQ
TFVLPLTDISEDVFKRNSIYAFKLRRQTVLRNNTAFSWPDLPDDAEVVYVELLHYCDDVPVMLETRHINLGAAPDARNID
FSTIAPSPWLMSNIPWSSVSHRISAISSGEELARALDLTPGAACMAIERKTYHLALPITRVRMVLAGDRMDLRGEYVLPT
L

Specific function: Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010248
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27408; Mature: 27277

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFEKGGSQSRVRQVEIELTGRILNGFYAHGERLPSEAELVKQFNVSRQTIHKALRELA
CCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
KFGLVERNRRAGTIVIRKFQQTFVLPLTDISEDVFKRNSIYAFKLRRQTVLRNNTAFSWP
HCCCCCCCCCCCEEEEEEEHHHEEEECHHCCHHHHHCCCEEEEEEHHHHHHHCCCCCCCC
DLPDDAEVVYVELLHYCDDVPVMLETRHINLGAAPDARNIDFSTIAPSPWLMSNIPWSSV
CCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHH
SHRISAISSGEELARALDLTPGAACMAIERKTYHLALPITRVRMVLAGDRMDLRGEYVLP
HHHHHHHCCHHHHHHHHCCCCCCEEEEEECCEEEEECHHHHHHHHHCCCCCCCCCCEECC
TL
CC
>Mature Secondary Structure 
TAFEKGGSQSRVRQVEIELTGRILNGFYAHGERLPSEAELVKQFNVSRQTIHKALRELA
CCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
KFGLVERNRRAGTIVIRKFQQTFVLPLTDISEDVFKRNSIYAFKLRRQTVLRNNTAFSWP
HCCCCCCCCCCCEEEEEEEHHHEEEECHHCCHHHHHCCCEEEEEEHHHHHHHCCCCCCCC
DLPDDAEVVYVELLHYCDDVPVMLETRHINLGAAPDARNIDFSTIAPSPWLMSNIPWSSV
CCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHH
SHRISAISSGEELARALDLTPGAACMAIERKTYHLALPITRVRMVLAGDRMDLRGEYVLP
HHHHHHHCCHHHHHHHHCCCCCCEEEEEECCEEEEECHHHHHHHHHCCCCCCCCCCEECC
TL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2203753 [H]