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The map label for this gene is adh [H]

Identifier: 110635259

GI number: 110635259

Start: 3186388

End: 3187428

Strand: Reverse

Name: adh [H]

Synonym: Meso_2930

Alternate gene names: 110635259

Gene position: 3187428-3186388 (Counterclockwise)

Preceding gene: 110635260

Following gene: 110635258

Centisome position: 72.24

GC content: 60.81

Gene sequence:

>1041_bases
ATGTATGCCGCCGTCATGCATGATTTCGGCGGTCCGGAAGTCATTGGCTGGGAAATGGTTCCTACGCCGCGACCCGGTCC
CCATGACGTTCTGGTGCAGGTACATGCTGTCACCGTAAACCGCACCCTGGATATAAAGGTGCGTCAGGGGGCGTATGCCA
AGCGCCCCGTTTTGCCGCATGTGTTAGGGGTCGATCCCTCAGGGGTCGTGGTGGAGACGGGGGCGGAGGTAAGCGACTTC
AAGCCCGGCGACCCCGTGGCTGTGTCATCCCGCATTCGCTATGAGCCCGAGGACGTGCCGCGGATGTTGGGTGTTGATCT
CTGGGGCGGCTATGCCGAGTATGTCTGTGTACCCGCTGCCAGTGCCTTTCCGTTGCCCGCGGGTCTTGATTTTGCAACAG
CCAGCATTGCCATTCGGCATGTCCCTCAAGCTTTCCATATGCTGGAGACAAAGGCGAAGCTGCAGCCGGGCGAATGGGTC
CTGGTCATGGGCGCCTCCGGCGGCCTCGGTAGCGCAAGTGTGCAGGTCGCCCGTCATCTGGGCGCGCGGGTGATTGTGGC
CGCCGGTGCGGACGAAAGGGTTTCCGCGGCGATGGCGCTGGGCGGGGAATTCGGGATCAATTATCGCAGCCAGGATCTGC
ACGCCGAGGTCATGCGTATCACCGGCAATGCAGGAGTCGATGTGGTTTGCGAGAATATCAGCGATCCGGTTCTATTCCCG
GCGGCATTTAAAAGCCTGCGCCGTTTCGGCCGACTGGTCAGCGTGGGCACTCACGGGGGCGGAATTGTTCCTCTCGATGT
TGCCTTTCTCTACCTCAACCAATTGACCATTATGGGATCGACCGGCCAGACGCCGGATGACATCCGCAAGGGTATTGAGC
TTGCGGCCAGCGGCAAGTTTCGGCCACTGATCGGCTGTGTGCTGCCGCTCTATCAGGTGCGCGAGGGGCATGTGTTGGCG
GACGGAAACGACGTGCTTGGAAAGGTTGTGCTTGATCCAAGGGCACGGCCAAACGGTGCTGCGCAGAGCCTTCGATCTTG
A

Upstream 100 bases:

>100_bases
TGGCTGCAAGAGGAATCCATGACCTGGGGATTGCCGCCTCTGCCGGACTTCCGGCGCCAACGCGAACAGGGATAGGCCGC
ACTCGATGGTAGAGGACAAG

Downstream 100 bases:

>100_bases
CATCAAGCCGATAGCAAAGTTGAGGAGACGGCGATGTGTAATGCGCTTTATGCCGGCATCGGTGGTAGACGCTGCCGTTT
GTTGTTCCCAGGCTCGCAGA

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MYAAVMHDFGGPEVIGWEMVPTPRPGPHDVLVQVHAVTVNRTLDIKVRQGAYAKRPVLPHVLGVDPSGVVVETGAEVSDF
KPGDPVAVSSRIRYEPEDVPRMLGVDLWGGYAEYVCVPAASAFPLPAGLDFATASIAIRHVPQAFHMLETKAKLQPGEWV
LVMGASGGLGSASVQVARHLGARVIVAAGADERVSAAMALGGEFGINYRSQDLHAEVMRITGNAGVDVVCENISDPVLFP
AAFKSLRRFGRLVSVGTHGGGIVPLDVAFLYLNQLTIMGSTGQTPDDIRKGIELAASGKFRPLIGCVLPLYQVREGHVLA
DGNDVLGKVVLDPRARPNGAAQSLRS

Sequences:

>Translated_346_residues
MYAAVMHDFGGPEVIGWEMVPTPRPGPHDVLVQVHAVTVNRTLDIKVRQGAYAKRPVLPHVLGVDPSGVVVETGAEVSDF
KPGDPVAVSSRIRYEPEDVPRMLGVDLWGGYAEYVCVPAASAFPLPAGLDFATASIAIRHVPQAFHMLETKAKLQPGEWV
LVMGASGGLGSASVQVARHLGARVIVAAGADERVSAAMALGGEFGINYRSQDLHAEVMRITGNAGVDVVCENISDPVLFP
AAFKSLRRFGRLVSVGTHGGGIVPLDVAFLYLNQLTIMGSTGQTPDDIRKGIELAASGKFRPLIGCVLPLYQVREGHVLA
DGNDVLGKVVLDPRARPNGAAQSLRS
>Mature_346_residues
MYAAVMHDFGGPEVIGWEMVPTPRPGPHDVLVQVHAVTVNRTLDIKVRQGAYAKRPVLPHVLGVDPSGVVVETGAEVSDF
KPGDPVAVSSRIRYEPEDVPRMLGVDLWGGYAEYVCVPAASAFPLPAGLDFATASIAIRHVPQAFHMLETKAKLQPGEWV
LVMGASGGLGSASVQVARHLGARVIVAAGADERVSAAMALGGEFGINYRSQDLHAEVMRITGNAGVDVVCENISDPVLFP
AAFKSLRRFGRLVSVGTHGGGIVPLDVAFLYLNQLTIMGSTGQTPDDIRKGIELAASGKFRPLIGCVLPLYQVREGHVLA
DGNDVLGKVVLDPRARPNGAAQSLRS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=344, Percent_Identity=31.9767441860465, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI13236495, Length=344, Percent_Identity=31.9767441860465, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI22538446, Length=339, Percent_Identity=28.023598820059, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI22538444, Length=339, Percent_Identity=28.023598820059, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI194239676, Length=338, Percent_Identity=29.8816568047337, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI18379349, Length=316, Percent_Identity=25.9493670886076, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI28557745, Length=246, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI24308257, Length=364, Percent_Identity=24.4505494505494, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI197927207, Length=198, Percent_Identity=29.2929292929293, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=265, Percent_Identity=27.9245283018868, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788075, Length=341, Percent_Identity=27.8592375366569, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081918, Length=327, Percent_Identity=26.9113149847095, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788073, Length=316, Percent_Identity=27.2151898734177, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790045, Length=256, Percent_Identity=27.734375, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI226510992, Length=305, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=213, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=309, Percent_Identity=23.6245954692557, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=309, Percent_Identity=24.9190938511327, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=263, Percent_Identity=28.8973384030418, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562878, Length=224, Percent_Identity=29.0178571428571, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=278, Percent_Identity=26.2589928057554, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=326, Percent_Identity=26.6871165644172, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=329, Percent_Identity=26.1398176291793, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=329, Percent_Identity=24.6200607902736, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=301, Percent_Identity=25.2491694352159, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36630; Mature: 36630

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAAVMHDFGGPEVIGWEMVPTPRPGPHDVLVQVHAVTVNRTLDIKVRQGAYAKRPVLPH
CCEEEEECCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCCCCCCCCCC
VLGVDPSGVVVETGAEVSDFKPGDPVAVSSRIRYEPEDVPRMLGVDLWGGYAEYVCVPAA
EECCCCCCEEEECCCCCCCCCCCCCEEECCEEECCCHHHHHHHCHHHCCCCEEEEEEECC
SAFPLPAGLDFATASIAIRHVPQAFHMLETKAKLQPGEWVLVMGASGGLGSASVQVARHL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHC
GARVIVAAGADERVSAAMALGGEFGINYRSQDLHAEVMRITGNAGVDVVCENISDPVLFP
CCEEEEEECCCHHHHHHHHCCCCCCCCCCCCHHHEEEEEEECCCCEEEEECCCCCCEECH
AAFKSLRRFGRLVSVGTHGGGIVPLDVAFLYLNQLTIMGSTGQTPDDIRKGIELAASGKF
HHHHHHHHHHHEEEECCCCCCEEHHHHHHHHHHHEEEECCCCCCHHHHHHHHEEECCCCC
RPLIGCVLPLYQVREGHVLADGNDVLGKVVLDPRARPNGAAQSLRS
HHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCCCCCHHHHHHCC
>Mature Secondary Structure
MYAAVMHDFGGPEVIGWEMVPTPRPGPHDVLVQVHAVTVNRTLDIKVRQGAYAKRPVLPH
CCEEEEECCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCCCCCCCCCC
VLGVDPSGVVVETGAEVSDFKPGDPVAVSSRIRYEPEDVPRMLGVDLWGGYAEYVCVPAA
EECCCCCCEEEECCCCCCCCCCCCCEEECCEEECCCHHHHHHHCHHHCCCCEEEEEEECC
SAFPLPAGLDFATASIAIRHVPQAFHMLETKAKLQPGEWVLVMGASGGLGSASVQVARHL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHC
GARVIVAAGADERVSAAMALGGEFGINYRSQDLHAEVMRITGNAGVDVVCENISDPVLFP
CCEEEEEECCCHHHHHHHHCCCCCCCCCCCCHHHEEEEEEECCCCEEEEECCCCCCEECH
AAFKSLRRFGRLVSVGTHGGGIVPLDVAFLYLNQLTIMGSTGQTPDDIRKGIELAASGKF
HHHHHHHHHHHEEEECCCCCCEEHHHHHHHHHHHEEEECCCCCCHHHHHHHHEEECCCCC
RPLIGCVLPLYQVREGHVLADGNDVLGKVVLDPRARPNGAAQSLRS
HHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA