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The map label for this gene is lacF [H]

Identifier: 110634994

GI number: 110634994

Start: 2879380

End: 2881146

Strand: Reverse

Name: lacF [H]

Synonym: Meso_2660

Alternate gene names: 110634994

Gene position: 2881146-2879380 (Counterclockwise)

Preceding gene: 110634995

Following gene: 110634993

Centisome position: 65.3

GC content: 61.18

Gene sequence:

>1767_bases
ATGACCGGAATGTTCAGAGCATGGGGTACATCCGTGCCGCGTTCGACGAGCGGCTATCTATCCGCTCTGCTGTGGATCAT
CGCTGCCGTCGTCGTGGTATGGCCGGTCGTCGCGCTGGTCATCGGCACCTTGTGGGACAGCGCGGTTGGAATGGATCCGA
ACTGGGGGTTCGGAGCCTTCCAACGGGCCGTCAACTCGCCGCGGTTCTTTCCTGCATTGCTGACCACCGCCCTCTTCTGC
ATTCTGGTCGTGCCGAGCTCCGTCTTTCTGGCCCTCATCCTCGCAACCCTCAGCCAGTTCTCCAACGCAAGACTGCGCTG
GCTCATTTCGCCGACATTGATCATCTCCTACACCATTCCGCCGCTCTTCTATTCGGTCGGCTACGCGCTCGTCGGCACCG
GGCGCGCAGGCGCAGGCAATGATCTGCTCAGCTATCTTGCGGGAACGTCCTTCACGCCGCTGAATCTGACGAGCTTTGCG
GGACTGATCTTCGTATCGATCCTGCGCGCCACCGCCTATGTCTATATTCTCCTGGTCGGCCCGCTTTCCACTGTCGGACA
GAGCCAGGACGAAGCGGCGCGCATCGCAGGCGGCGGTTCGTGGGTCCGCTTGACCATGCTGGTCTCGACATTGAAGCCGA
GCATCGCGGCGGCGACCGTGCTCGTCACCATCGGCACAGTGCAGGTATTCGACGCCGTCTACATTCTCGGCAGCAACGTC
AACATCTATACTTTGTCGACGCTGACCTATGGCCTGCTCCAACAGCAGCAGGCCGATTTTCCTGCCGCGACGGCGATCGG
AACCATGCTGCTGGCTTTGGTCGCGGTGCTGATCCTCTTGCAAAACTTTGCCACGAGGAGCGGCCGCTTCACGACGGTTG
CCGTCAAGCCCGAAGCGCGGCTCCGCCTTTCGCTCGGGCCCTGGCGTCCCGTCTTCGAAATCTTCATCGTCCTCTATTTC
GTCTTTTCGCTGCTGGTGCCCGTCTGCTCGCTGTTGGTGACCTCGGTCATTCCGTTCCCCGGCGTCTACAACAGCTTCAC
TTTCGCCAATTACACCCGCATCTGGAGCGATACCACCATCCTGCATGCGGCGATGACCACCTTCATTCTCGCCAATTCCG
GGGCCGTGGCTGCTGTCGTCTTCGCGATGATGATGATCCGGCTCAGAGCGCGCCAGGCGAGAGAAAGCGGCCGGGTTCTG
GTCGATGTGATTATGCTCGCACCGAAGGTCATGCACGGCATCGTCACAGCGCTCGCCTTTATCTGGGCGGTGACGATTTT
TTCCGCCACTCGCGGCCTCTACGGGACGGGATTCCTGATGTTCCTGGCCCTGACGGTCAGCGTCGTGCCGGTCTCCTATC
TGCTGATAAGCTCCGCCTATGCGCAGGTCGACAGTTCACTCGAACATGCCGCCAGAATTTCGGGCTCGCATCCTCTCCAT
GCGCAATTGCGCATTCAGGTCCCGCTGTTGGCGCCGACTCTCGCCAATGCCTGGTTCCTGAGCGCGGTGTTCATCGCCGG
CTCTCTCGATATCCCGTTGGTCCTCGGCTCGGTCAATCTGCGGGTGATCGCGACGACCGTGTTCGAGCTTTACTCGCTGA
GCGGCGATTATGGCGCCGCGGCAGCGCTGCTCGTCAGCATGCTGATTGTCTTCGCCATCACGGCCCTTCTCGTCCGCGGA
TTCGTTCTGCTCATCCGTGCAGACCTGCGTCCGTGGCGATCGGCCCGAACGCGACCGGCGCTCGCTCAAGGAGGTGTCAC
GGCATGA

Upstream 100 bases:

>100_bases
GGAGGTTGAAAGGGGCTGACGCAAGGCCCGCTAATGTCCATGACCGAAGCGTCAGGCAACAATAAGCACAAGAGCAGAAG
CTCAGCCAGAGGGTGAACAT

Downstream 100 bases:

>100_bases
ATGTTTCATCGATCTCCCGCTACGGCGAAGTCATCAACCCGGAGGTTTACGGTTTGCACGCGATTTCCGATCCACGGCAA
GATGAAGGCGCGATCGTCGT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MTGMFRAWGTSVPRSTSGYLSALLWIIAAVVVVWPVVALVIGTLWDSAVGMDPNWGFGAFQRAVNSPRFFPALLTTALFC
ILVVPSSVFLALILATLSQFSNARLRWLISPTLIISYTIPPLFYSVGYALVGTGRAGAGNDLLSYLAGTSFTPLNLTSFA
GLIFVSILRATAYVYILLVGPLSTVGQSQDEAARIAGGGSWVRLTMLVSTLKPSIAAATVLVTIGTVQVFDAVYILGSNV
NIYTLSTLTYGLLQQQQADFPAATAIGTMLLALVAVLILLQNFATRSGRFTTVAVKPEARLRLSLGPWRPVFEIFIVLYF
VFSLLVPVCSLLVTSVIPFPGVYNSFTFANYTRIWSDTTILHAAMTTFILANSGAVAAVVFAMMMIRLRARQARESGRVL
VDVIMLAPKVMHGIVTALAFIWAVTIFSATRGLYGTGFLMFLALTVSVVPVSYLLISSAYAQVDSSLEHAARISGSHPLH
AQLRIQVPLLAPTLANAWFLSAVFIAGSLDIPLVLGSVNLRVIATTVFELYSLSGDYGAAAALLVSMLIVFAITALLVRG
FVLLIRADLRPWRSARTRPALAQGGVTA

Sequences:

>Translated_588_residues
MTGMFRAWGTSVPRSTSGYLSALLWIIAAVVVVWPVVALVIGTLWDSAVGMDPNWGFGAFQRAVNSPRFFPALLTTALFC
ILVVPSSVFLALILATLSQFSNARLRWLISPTLIISYTIPPLFYSVGYALVGTGRAGAGNDLLSYLAGTSFTPLNLTSFA
GLIFVSILRATAYVYILLVGPLSTVGQSQDEAARIAGGGSWVRLTMLVSTLKPSIAAATVLVTIGTVQVFDAVYILGSNV
NIYTLSTLTYGLLQQQQADFPAATAIGTMLLALVAVLILLQNFATRSGRFTTVAVKPEARLRLSLGPWRPVFEIFIVLYF
VFSLLVPVCSLLVTSVIPFPGVYNSFTFANYTRIWSDTTILHAAMTTFILANSGAVAAVVFAMMMIRLRARQARESGRVL
VDVIMLAPKVMHGIVTALAFIWAVTIFSATRGLYGTGFLMFLALTVSVVPVSYLLISSAYAQVDSSLEHAARISGSHPLH
AQLRIQVPLLAPTLANAWFLSAVFIAGSLDIPLVLGSVNLRVIATTVFELYSLSGDYGAAAALLVSMLIVFAITALLVRG
FVLLIRADLRPWRSARTRPALAQGGVTA
>Mature_587_residues
TGMFRAWGTSVPRSTSGYLSALLWIIAAVVVVWPVVALVIGTLWDSAVGMDPNWGFGAFQRAVNSPRFFPALLTTALFCI
LVVPSSVFLALILATLSQFSNARLRWLISPTLIISYTIPPLFYSVGYALVGTGRAGAGNDLLSYLAGTSFTPLNLTSFAG
LIFVSILRATAYVYILLVGPLSTVGQSQDEAARIAGGGSWVRLTMLVSTLKPSIAAATVLVTIGTVQVFDAVYILGSNVN
IYTLSTLTYGLLQQQQADFPAATAIGTMLLALVAVLILLQNFATRSGRFTTVAVKPEARLRLSLGPWRPVFEIFIVLYFV
FSLLVPVCSLLVTSVIPFPGVYNSFTFANYTRIWSDTTILHAAMTTFILANSGAVAAVVFAMMMIRLRARQARESGRVLV
DVIMLAPKVMHGIVTALAFIWAVTIFSATRGLYGTGFLMFLALTVSVVPVSYLLISSAYAQVDSSLEHAARISGSHPLHA
QLRIQVPLLAPTLANAWFLSAVFIAGSLDIPLVLGSVNLRVIATTVFELYSLSGDYGAAAALLVSMLIVFAITALLVRGF
VLLIRADLRPWRSARTRPALAQGGVTA

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1178

COG function: function code P; ABC-type Fe3+ transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 63037; Mature: 62906

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMFRAWGTSVPRSTSGYLSALLWIIAAVVVVWPVVALVIGTLWDSAVGMDPNWGFGAF
CCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QRAVNSPRFFPALLTTALFCILVVPSSVFLALILATLSQFSNARLRWLISPTLIISYTIP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECHH
PLFYSVGYALVGTGRAGAGNDLLSYLAGTSFTPLNLTSFAGLIFVSILRATAYVYILLVG
HHHHHHCHHHEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PLSTVGQSQDEAARIAGGGSWVRLTMLVSTLKPSIAAATVLVTIGTVQVFDAVYILGSNV
CHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
NIYTLSTLTYGLLQQQQADFPAATAIGTMLLALVAVLILLQNFATRSGRFTTVAVKPEAR
EEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCE
LRLSLGPWRPVFEIFIVLYFVFSLLVPVCSLLVTSVIPFPGVYNSFTFANYTRIWSDTTI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHH
LHAAMTTFILANSGAVAAVVFAMMMIRLRARQARESGRVLVDVIMLAPKVMHGIVTALAF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IWAVTIFSATRGLYGTGFLMFLALTVSVVPVSYLLISSAYAQVDSSLEHAARISGSHPLH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AQLRIQVPLLAPTLANAWFLSAVFIAGSLDIPLVLGSVNLRVIATTVFELYSLSGDYGAA
EEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHH
AALLVSMLIVFAITALLVRGFVLLIRADLRPWRSARTRPALAQGGVTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGMFRAWGTSVPRSTSGYLSALLWIIAAVVVVWPVVALVIGTLWDSAVGMDPNWGFGAF
CCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QRAVNSPRFFPALLTTALFCILVVPSSVFLALILATLSQFSNARLRWLISPTLIISYTIP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECHH
PLFYSVGYALVGTGRAGAGNDLLSYLAGTSFTPLNLTSFAGLIFVSILRATAYVYILLVG
HHHHHHCHHHEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PLSTVGQSQDEAARIAGGGSWVRLTMLVSTLKPSIAAATVLVTIGTVQVFDAVYILGSNV
CHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
NIYTLSTLTYGLLQQQQADFPAATAIGTMLLALVAVLILLQNFATRSGRFTTVAVKPEAR
EEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCE
LRLSLGPWRPVFEIFIVLYFVFSLLVPVCSLLVTSVIPFPGVYNSFTFANYTRIWSDTTI
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHH
LHAAMTTFILANSGAVAAVVFAMMMIRLRARQARESGRVLVDVIMLAPKVMHGIVTALAF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IWAVTIFSATRGLYGTGFLMFLALTVSVVPVSYLLISSAYAQVDSSLEHAARISGSHPLH
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AQLRIQVPLLAPTLANAWFLSAVFIAGSLDIPLVLGSVNLRVIATTVFELYSLSGDYGAA
EEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHH
AALLVSMLIVFAITALLVRGFVLLIRADLRPWRSARTRPALAQGGVTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]