Click here to switch to the map view.

The map label for this gene is tobS2 [H]

Identifier: 110634925

GI number: 110634925

Start: 2783749

End: 2784927

Strand: Reverse

Name: tobS2 [H]

Synonym: Meso_2584

Alternate gene names: 110634925

Gene position: 2784927-2783749 (Counterclockwise)

Preceding gene: 110634927

Following gene: 110634924

Centisome position: 63.12

GC content: 61.83

Gene sequence:

>1179_bases
ATGGCAAAGGTCGGTTTGCGGGAGTGGTTTGCGGTCGGGCGGGTTATCGCATCCGGGCACCTGGCGCGGTATAGCGGCGT
GGGTGAAGGACCGCTAACGCGATTTGAGGCGGATTATTCGGAGAAATTCGGTGTCAAGCACACGCTCGCCGTGAGCAGCG
GCACCGCCGCACTCATCTCGGCGCTCGCTGCGGCGGGCGTAGGGCCGGGCGACGAGGTTCTGGTGCCCGCCTATACCTGG
ATCGCCACCGCGGCCGCGCCGCTGGCGGTCGGCGCCGTTCCGGTGCTTGTCGATATCGACCAGACGCTGACCATTGATCC
CGCGGACATCCTGCGCAAGATCACGCCGCGCACGCGCGCTATCCTGCCGGTGCATATGGCGAATATGGTCTGCGACATGG
ATCGGATCATGGAGATCGCCCGTGAGCGTGGGCTTCTCGTGATCGAGGATGCCTGTCAGGCGGTCGGTGTCACATATAAG
GGCCGGCGGGTGGGCACCATCGGAGATATCGGCGCCTACAGCTTCAACCAGTTCAAGAACATGAACGTCGGCGAGGGTGG
GGCGGTCGTCACAAATGAGGACCGGTATTACGTCCGCGCCCGTATGTATCACGATGTCGGTTCCATCTTTCGCGGTCACC
TCGATAATGAAAACGAGCCGCATTTCTTCGGGGTCAATTTCAAGGCCAGCCAAATTCAGGGTGCCATGCTCAACGTCCAG
CTCGCCAAGCTCGATCCAATGCTGGCTCGCATGCGGGCTCGCTATCGGTTGATGACCCGGGTGCTGGCGGCCTCGTCCGC
ATTCAGGATCGGTCCGCATAACGATGTCGAGAATGCCGTCGGACTGCATGTGATCTTCAATACAGCGGAAGAGGCCGCAG
ATTTTGCGGCCCGGAACAAGCGCGGCGTCTACCGGCTCTACGATTCAAGCCGGCACGTTTATACGAACTGGCTGCCGGTG
CTTGAGCAGCGCGCGGCCCATCCTGAAATGAACCCGTTCGCATGGGCCTCACGGAAAGTCGAATATGCGCCGGATATGTG
CGCGCGCACGCTCGACATCCTGCAGCGCAGCTGCCGCATCAGCCTCGGCGAAAACTATCCTCTGCCGCTTGTGGCTTATG
TCGCCCGGCGGCTCGCCAGCGGTGGCGAGGCAGCAAGGCAGGTGTCCTATGCGGTATAG

Upstream 100 bases:

>100_bases
AAATAGTCTTGGAAATCGAAAATTGGTTGGGAATTGGGGGGCTTCGTCGGGAGAACTTTCGCTCGGCGGCCTTTCTCGTT
TCAGATTCGGGATGTCCGGG

Downstream 100 bases:

>100_bases
CCCCGTCACGATCGGACCGGACGTCATCGATCTCTGGAGATGGCCTCTCGATGTCATTGCCGGTGAACTGCCGCGATATG
TGGAGGCGCTGAGCGATACG

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: TDP-D-fucosamine; 2-oxoglutarate [C]

Alternate protein names: Putative L-glutamine:amino-DOI aminotransferase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MAKVGLREWFAVGRVIASGHLARYSGVGEGPLTRFEADYSEKFGVKHTLAVSSGTAALISALAAAGVGPGDEVLVPAYTW
IATAAAPLAVGAVPVLVDIDQTLTIDPADILRKITPRTRAILPVHMANMVCDMDRIMEIARERGLLVIEDACQAVGVTYK
GRRVGTIGDIGAYSFNQFKNMNVGEGGAVVTNEDRYYVRARMYHDVGSIFRGHLDNENEPHFFGVNFKASQIQGAMLNVQ
LAKLDPMLARMRARYRLMTRVLAASSAFRIGPHNDVENAVGLHVIFNTAEEAADFAARNKRGVYRLYDSSRHVYTNWLPV
LEQRAAHPEMNPFAWASRKVEYAPDMCARTLDILQRSCRISLGENYPLPLVAYVARRLASGGEAARQVSYAV

Sequences:

>Translated_392_residues
MAKVGLREWFAVGRVIASGHLARYSGVGEGPLTRFEADYSEKFGVKHTLAVSSGTAALISALAAAGVGPGDEVLVPAYTW
IATAAAPLAVGAVPVLVDIDQTLTIDPADILRKITPRTRAILPVHMANMVCDMDRIMEIARERGLLVIEDACQAVGVTYK
GRRVGTIGDIGAYSFNQFKNMNVGEGGAVVTNEDRYYVRARMYHDVGSIFRGHLDNENEPHFFGVNFKASQIQGAMLNVQ
LAKLDPMLARMRARYRLMTRVLAASSAFRIGPHNDVENAVGLHVIFNTAEEAADFAARNKRGVYRLYDSSRHVYTNWLPV
LEQRAAHPEMNPFAWASRKVEYAPDMCARTLDILQRSCRISLGENYPLPLVAYVARRLASGGEAARQVSYAV
>Mature_391_residues
AKVGLREWFAVGRVIASGHLARYSGVGEGPLTRFEADYSEKFGVKHTLAVSSGTAALISALAAAGVGPGDEVLVPAYTWI
ATAAAPLAVGAVPVLVDIDQTLTIDPADILRKITPRTRAILPVHMANMVCDMDRIMEIARERGLLVIEDACQAVGVTYKG
RRVGTIGDIGAYSFNQFKNMNVGEGGAVVTNEDRYYVRARMYHDVGSIFRGHLDNENEPHFFGVNFKASQIQGAMLNVQL
AKLDPMLARMRARYRLMTRVLAASSAFRIGPHNDVENAVGLHVIFNTAEEAADFAARNKRGVYRLYDSSRHVYTNWLPVL
EQRAAHPEMNPFAWASRKVEYAPDMCARTLDILQRSCRISLGENYPLPLVAYVARRLASGGEAARQVSYAV

Specific function: Catalyzes the transamination of 3-amino-2,3-dideoxy- scyllo-inosose (amino-DOI) into 2-deoxystreptamine (DOS) (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. L-glutamine:2- deoxy-scyllo-inosose/scyllo-inosose aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI2367285, Length=226, Percent_Identity=40.2654867256637, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI145693159, Length=257, Percent_Identity=36.1867704280156, Blast_Score=141, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 42985; Mature: 42854

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVGLREWFAVGRVIASGHLARYSGVGEGPLTRFEADYSEKFGVKHTLAVSSGTAALIS
CCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHCCCEEEEEECCCHHHHHH
ALAAAGVGPGDEVLVPAYTWIATAAAPLAVGAVPVLVDIDQTLTIDPADILRKITPRTRA
HHHHCCCCCCCCEEECHHHHHHHHHHHHHHCCEEEEEECCCEEEECHHHHHHHCCCCHHE
ILPVHMANMVCDMDRIMEIARERGLLVIEDACQAVGVTYKGRRVGTIGDIGAYSFNQFKN
EEHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHCCEECCCEECCCCCCCCCCHHHHCC
MNVGEGGAVVTNEDRYYVRARMYHDVGSIFRGHLDNENEPHFFGVNFKASQIQGAMLNVQ
CCCCCCCEEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEEECEEHHHCCCEEEEEE
LAKLDPMLARMRARYRLMTRVLAASSAFRIGPHNDVENAVGLHVIFNTAEEAADFAARNK
HHHHCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHCCEEEEEECCHHHHHHHHHHCC
RGVYRLYDSSRHVYTNWLPVLEQRAAHPEMNPFAWASRKVEYAPDMCARTLDILQRSCRI
CCEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCE
SLGENYPLPLVAYVARRLASGGEAARQVSYAV
ECCCCCCCHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
AKVGLREWFAVGRVIASGHLARYSGVGEGPLTRFEADYSEKFGVKHTLAVSSGTAALIS
CCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHCCCEEEEEECCCHHHHHH
ALAAAGVGPGDEVLVPAYTWIATAAAPLAVGAVPVLVDIDQTLTIDPADILRKITPRTRA
HHHHCCCCCCCCEEECHHHHHHHHHHHHHHCCEEEEEECCCEEEECHHHHHHHCCCCHHE
ILPVHMANMVCDMDRIMEIARERGLLVIEDACQAVGVTYKGRRVGTIGDIGAYSFNQFKN
EEHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHCCEECCCEECCCCCCCCCCHHHHCC
MNVGEGGAVVTNEDRYYVRARMYHDVGSIFRGHLDNENEPHFFGVNFKASQIQGAMLNVQ
CCCCCCCEEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEEECEEHHHCCCEEEEEE
LAKLDPMLARMRARYRLMTRVLAASSAFRIGPHNDVENAVGLHVIFNTAEEAADFAARNK
HHHHCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHCCEEEEEECCHHHHHHHHHHCC
RGVYRLYDSSRHVYTNWLPVLEQRAAHPEMNPFAWASRKVEYAPDMCARTLDILQRSCRI
CCEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCE
SLGENYPLPLVAYVARRLASGGEAARQVSYAV
ECCCCCCCHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose; L-glutamate [C]

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-D-fucosamine + 2-oxoglutarate [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA