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The map label for this gene is dapA [H]

Identifier: 110634909

GI number: 110634909

Start: 2756908

End: 2757822

Strand: Reverse

Name: dapA [H]

Synonym: Meso_2568

Alternate gene names: 110634909

Gene position: 2757822-2756908 (Counterclockwise)

Preceding gene: 110634910

Following gene: 110634908

Centisome position: 62.5

GC content: 60.87

Gene sequence:

>915_bases
ATGCAAAAGAGCGACTTCCGCGGCATCTTCCCCGCAATAACCACCAAGATGACGGCTGATCAGCAAGTGGATCTCGACGG
CGTCCGGGCGGATATTGCCTTCCAGATCGAGAGCGGGGTGGACGCTGTCGTCCTTTGCGGCTCCTTGGGGGAGGCTTCGA
GCCTGACACGCGAAGAGAAGATCGCCATCGCCAAGGCTGCGAAGGAGGAGGCGAGGGGGCTCGTGCCGATTATCCTAACA
ATCGCGGAGGATTCGACGGCTGCGGGTGCATCGCTCGCTGCAGAGGCCGAAAAGATCGGGGTCGACGGCCTCATGGTGCT
GCCGGCTATGCGCTATCTCGCCGACGACCGCGAAGTGGTGACGCACTACCGCGCCGTGGCGGCCGCCTCGAACCTGCCGA
TCATCGTCTATAACAACCCGCTTGCCTACGGCATCAACATCACAACTGCGATGCTGAAGGAGATGGCGGACGAAGCCAAA
TTCGTCGCCATTAAGGAATCCACCGGCGATACGCGGCGCATCAACGAGACCATCAACGCGCTTGGCGACCGTTATCAGCT
TTTGACCGGCGTGGACGATCTGGCGCTGGAAAGCCTGGTCCTCGGCTGCTCCGGCTGGATAGCAGGCCTGGTCGTAGCCT
TCCCGAAGGAGACGGTTGCGATATACAAGCTCGTGGAAGAGGGCCGTCTCAAAGAGGCGCTGGAGATCTACCGATGGTTC
CTGCCGTTGCTCCACCTCGATATCGGGCCAAAATTCGTCCAGAAGATCAAGCTTTGCGAGCACATCGTGCGCGGCACCTC
ACCGGTGGTGCGCCAGCCGCGCCTTCAACTTATCGGGCAGGAAGAGGCGGAGGTCCGCGCTGTGGTGGAGACAGGGCTCA
GGAACCGTCCCGATCTGGGCAGATACGGCTTATAA

Upstream 100 bases:

>100_bases
CATCGCCGCGCATCCGGCACGCATCGGTTTTGTGTCGACAAACTAAATACAAGCTAATAAGCTGAAGCATGCGCCGGTTC
GCGTTCGAAAGAGGAATGGT

Downstream 100 bases:

>100_bases
CGCCAAGAATCGTCACCCATTCGGCTCGAGTAGCAAGATCCCGTATTTGGGGTCAGGCGCAGCTGCGCAGAGGCGAGAGA
CGCTGACGAGCGCCAAAGCC

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MQKSDFRGIFPAITTKMTADQQVDLDGVRADIAFQIESGVDAVVLCGSLGEASSLTREEKIAIAKAAKEEARGLVPIILT
IAEDSTAAGASLAAEAEKIGVDGLMVLPAMRYLADDREVVTHYRAVAAASNLPIIVYNNPLAYGINITTAMLKEMADEAK
FVAIKESTGDTRRINETINALGDRYQLLTGVDDLALESLVLGCSGWIAGLVVAFPKETVAIYKLVEEGRLKEALEIYRWF
LPLLHLDIGPKFVQKIKLCEHIVRGTSPVVRQPRLQLIGQEEAEVRAVVETGLRNRPDLGRYGL

Sequences:

>Translated_304_residues
MQKSDFRGIFPAITTKMTADQQVDLDGVRADIAFQIESGVDAVVLCGSLGEASSLTREEKIAIAKAAKEEARGLVPIILT
IAEDSTAAGASLAAEAEKIGVDGLMVLPAMRYLADDREVVTHYRAVAAASNLPIIVYNNPLAYGINITTAMLKEMADEAK
FVAIKESTGDTRRINETINALGDRYQLLTGVDDLALESLVLGCSGWIAGLVVAFPKETVAIYKLVEEGRLKEALEIYRWF
LPLLHLDIGPKFVQKIKLCEHIVRGTSPVVRQPRLQLIGQEEAEVRAVVETGLRNRPDLGRYGL
>Mature_304_residues
MQKSDFRGIFPAITTKMTADQQVDLDGVRADIAFQIESGVDAVVLCGSLGEASSLTREEKIAIAKAAKEEARGLVPIILT
IAEDSTAAGASLAAEAEKIGVDGLMVLPAMRYLADDREVVTHYRAVAAASNLPIIVYNNPLAYGINITTAMLKEMADEAK
FVAIKESTGDTRRINETINALGDRYQLLTGVDDLALESLVLGCSGWIAGLVVAFPKETVAIYKLVEEGRLKEALEIYRWF
LPLLHLDIGPKFVQKIKLCEHIVRGTSPVVRQPRLQLIGQEEAEVRAVVETGLRNRPDLGRYGL

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=238, Percent_Identity=22.6890756302521, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1786463, Length=287, Percent_Identity=28.5714285714286, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082415, Length=242, Percent_Identity=27.6859504132231, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788823, Length=286, Percent_Identity=25.5244755244755, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789620, Length=272, Percent_Identity=26.4705882352941, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33075; Mature: 33075

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSDFRGIFPAITTKMTADQQVDLDGVRADIAFQIESGVDAVVLCGSLGEASSLTREEK
CCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCHHHHHHHHH
IAIAKAAKEEARGLVPIILTIAEDSTAAGASLAAEAEKIGVDGLMVLPAMRYLADDREVV
HHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
THYRAVAAASNLPIIVYNNPLAYGINITTAMLKEMADEAKFVAIKESTGDTRRINETINA
HHHHHHHHCCCCCEEEECCCEEECCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHH
LGDRYQLLTGVDDLALESLVLGCSGWIAGLVVAFPKETVAIYKLVEEGRLKEALEIYRWF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHH
LPLLHLDIGPKFVQKIKLCEHIVRGTSPVVRQPRLQLIGQEEAEVRAVVETGLRNRPDLG
HHHHHHCCCHHHHHHHHHHHHHHHCCCCHHCCCHHHHCCCCHHHHHHHHHHCCCCCCCCC
RYGL
CCCC
>Mature Secondary Structure
MQKSDFRGIFPAITTKMTADQQVDLDGVRADIAFQIESGVDAVVLCGSLGEASSLTREEK
CCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCHHHHHHHHH
IAIAKAAKEEARGLVPIILTIAEDSTAAGASLAAEAEKIGVDGLMVLPAMRYLADDREVV
HHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
THYRAVAAASNLPIIVYNNPLAYGINITTAMLKEMADEAKFVAIKESTGDTRRINETINA
HHHHHHHHCCCCCEEEECCCEEECCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHH
LGDRYQLLTGVDDLALESLVLGCSGWIAGLVVAFPKETVAIYKLVEEGRLKEALEIYRWF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHH
LPLLHLDIGPKFVQKIKLCEHIVRGTSPVVRQPRLQLIGQEEAEVRAVVETGLRNRPDLG
HHHHHHCCCHHHHHHHHHHHHHHHCCCCHHCCCHHHHCCCCHHHHHHHHHHCCCCCCCCC
RYGL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA