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The map label for this gene is fdoI [H]

Identifier: 110634792

GI number: 110634792

Start: 2627324

End: 2628343

Strand: Direct

Name: fdoI [H]

Synonym: Meso_2451

Alternate gene names: 110634792

Gene position: 2627324-2628343 (Clockwise)

Preceding gene: 110634791

Following gene: 110634795

Centisome position: 59.54

GC content: 61.18

Gene sequence:

>1020_bases
ATGCGCATCTGGAGGCTTGGTCAACTGATTGCGCCGGTTGTCGCAGCATTCATTCTTGCTGTCGGTCTGGTTGTCGTTCC
GGCGGGAGCACAGGAGGGGTCGTCGGGAAGCAATCCGACCGCCCAGGCGGTGAACGAGCAGCAACTCCTGAACGAGCTGC
AGAAGATCGAGGGGCGCGTCAGCCTACCCAACACGGCGGCCGGTTTGCTCCAGCAGCCGCAAGGGCGTGATTATCGTGCT
TTCCACGAGGGCGCACTGCCCTGGATCGGTGGCATCGTCATCATCGGTATGCTTCTGTTGCTGGCGCTGTTCTACTTCGT
CAGGGGCCGCATCCGCACGCTGGCCGGTGAATCGGGCGTCAAGATCCTGCGCTTCAATGCAATCGAACGGCTCGCCCATT
GGACCACGGCTACGGCCTTCATCATCCTTGCCATCACCGGCCTGAACTTCATCTTCGGCAAGCGCCTGCTTATGCCTTTG
ATCGGGCCGGAAGCGTTCTCCACATGGTCCATCTGGGCGAAATACGCGCACGATTTCGTTGCCTGGGCTTTCATGCTCGG
CGTGCTGGTTATGCTGGTCGCCTGGGTGTGGGACAACCTCCCGGACCGCTATGACGTGAATTGGCTGAAGGTCGGCGGCG
GATTTTTCGACCGGTCGAACAGGACGCACCCGCCAGCGAGACGCTTCAACACCGGCCAGAAACTCATCTTCTGGGCCGTC
GTGTTGGGGGGCATTGCGCTGTCGGTGTCCGGCATCTTCATGCTGTTTCCGTTCGCTTTCACCGACATCAATGGAATGCA
GACGGCCCAATATGTCCATGCGACCGTGGGCGTCATCCTGATCGGGGTGATCATCGCACACATTTATATCGGCACGCTCG
GCATGGAAGGCGCCTACGAGGCCATGGGCTCGGGCACCGTCGACCTGAACTGGGCCAAGGAGCACCACAGCGCCTGGGTG
GAGGAGCAGCAGGCAAAGTCAGGCGCGCTGCCGCGCGCTGCTGCGGAACCAGCCGAGTAA

Upstream 100 bases:

>100_bases
CAGCCAGAGCGAAGGCGCGAACATGGAGGAGCGCATTCGCTCCAGCACTGAAGGCGGTGGGCTGATCCCGCCGGTGCAGC
AGCTCAGGAGGACGGAGGAA

Downstream 100 bases:

>100_bases
CGGAACCATACCTGCAGCAAAACGCCCGGACGAAGGTCCGGGCGTTTTCTTTCGCCTCTGTGCCATCCTGCGGTCAGGAG
GCGGTCTCGCCGTCAGCGGC

Product: formate dehydrogenase gamma subunit

Products: CO2; NADH

Alternate protein names: Aerobic formate dehydrogenase cytochrome b556 subunit; FDH-Z subunit gamma; Formate dehydrogenase-O subunit gamma [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRIWRLGQLIAPVVAAFILAVGLVVVPAGAQEGSSGSNPTAQAVNEQQLLNELQKIEGRVSLPNTAAGLLQQPQGRDYRA
FHEGALPWIGGIVIIGMLLLLALFYFVRGRIRTLAGESGVKILRFNAIERLAHWTTATAFIILAITGLNFIFGKRLLMPL
IGPEAFSTWSIWAKYAHDFVAWAFMLGVLVMLVAWVWDNLPDRYDVNWLKVGGGFFDRSNRTHPPARRFNTGQKLIFWAV
VLGGIALSVSGIFMLFPFAFTDINGMQTAQYVHATVGVILIGVIIAHIYIGTLGMEGAYEAMGSGTVDLNWAKEHHSAWV
EEQQAKSGALPRAAAEPAE

Sequences:

>Translated_339_residues
MRIWRLGQLIAPVVAAFILAVGLVVVPAGAQEGSSGSNPTAQAVNEQQLLNELQKIEGRVSLPNTAAGLLQQPQGRDYRA
FHEGALPWIGGIVIIGMLLLLALFYFVRGRIRTLAGESGVKILRFNAIERLAHWTTATAFIILAITGLNFIFGKRLLMPL
IGPEAFSTWSIWAKYAHDFVAWAFMLGVLVMLVAWVWDNLPDRYDVNWLKVGGGFFDRSNRTHPPARRFNTGQKLIFWAV
VLGGIALSVSGIFMLFPFAFTDINGMQTAQYVHATVGVILIGVIIAHIYIGTLGMEGAYEAMGSGTVDLNWAKEHHSAWV
EEQQAKSGALPRAAAEPAE
>Mature_339_residues
MRIWRLGQLIAPVVAAFILAVGLVVVPAGAQEGSSGSNPTAQAVNEQQLLNELQKIEGRVSLPNTAAGLLQQPQGRDYRA
FHEGALPWIGGIVIIGMLLLLALFYFVRGRIRTLAGESGVKILRFNAIERLAHWTTATAFIILAITGLNFIFGKRLLMPL
IGPEAFSTWSIWAKYAHDFVAWAFMLGVLVMLVAWVWDNLPDRYDVNWLKVGGGFFDRSNRTHPPARRFNTGQKLIFWAV
VLGGIALSVSGIFMLFPFAFTDINGMQTAQYVHATVGVILIGVIIAHIYIGTLGMEGAYEAMGSGTVDLNWAKEHHSAWV
EEQQAKSGALPRAAAEPAE

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the formate dehydrogenase [H]

COG id: COG2864

COG function: function code C; Cytochrome b subunit of formate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the formate dehydrogenase gamma subunit family [H]

Homologues:

Organism=Escherichia coli, GI1790325, Length=210, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787750, Length=214, Percent_Identity=28.9719626168224, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005797
- InterPro:   IPR016174
- InterPro:   IPR006471 [H]

Pfam domain/function: PF00033 Cytochrom_B_N [H]

EC number: 1.2.1.2

Molecular weight: Translated: 37080; Mature: 37080

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIWRLGQLIAPVVAAFILAVGLVVVPAGAQEGSSGSNPTAQAVNEQQLLNELQKIEGRV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCC
SLPNTAAGLLQQPQGRDYRAFHEGALPWIGGIVIIGMLLLLALFYFVRGRIRTLAGESGV
CCCCHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KILRFNAIERLAHWTTATAFIILAITGLNFIFGKRLLMPLIGPEAFSTWSIWAKYAHDFV
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AWAFMLGVLVMLVAWVWDNLPDRYDVNWLKVGGGFFDRSNRTHPPARRFNTGQKLIFWAV
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEECCCCCCCCCHHHCCCCHHHHHHHH
VLGGIALSVSGIFMLFPFAFTDINGMQTAQYVHATVGVILIGVIIAHIYIGTLGMEGAYE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AMGSGTVDLNWAKEHHSAWVEEQQAKSGALPRAAAEPAE
HHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRIWRLGQLIAPVVAAFILAVGLVVVPAGAQEGSSGSNPTAQAVNEQQLLNELQKIEGRV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCC
SLPNTAAGLLQQPQGRDYRAFHEGALPWIGGIVIIGMLLLLALFYFVRGRIRTLAGESGV
CCCCHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KILRFNAIERLAHWTTATAFIILAITGLNFIFGKRLLMPLIGPEAFSTWSIWAKYAHDFV
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AWAFMLGVLVMLVAWVWDNLPDRYDVNWLKVGGGFFDRSNRTHPPARRFNTGQKLIFWAV
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEECCCCCCCCCHHHCCCCHHHHHHHH
VLGGIALSVSGIFMLFPFAFTDINGMQTAQYVHATVGVILIGVIIAHIYIGTLGMEGAYE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AMGSGTVDLNWAKEHHSAWVEEQQAKSGALPRAAAEPAE
HHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]